1RUA

Crystal structure (B) of u.v.-irradiated cationic cyclization antibody 4C6 fab at pH 4.6 with a data set collected at SSRL beamline 11-1.

Functional Information from GO Data

Chain	GOid	namespace	contents
L	0005615	cellular_component	extracellular space
L	0006955	biological_process	immune response
L	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ACT L 611

Chain	Residue
H	LEU95
H	TRP103
L	ASN34
L	TRP89
L	HOH637

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site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE BEZ H 601

Chain	Residue
L	TRP89
L	GLY91
L	TYR96
H	ALA34
H	ASN35
H	LEU95
H	PRO230

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site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL L 621

Chain	Residue
H	PRO175
H	THR186
H	LEU187
H	SER188
L	SER162
L	SER176
L	THR178
L	HOH705

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site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL H 622

Chain	Residue
H	ARG71
H	ASP72
H	THR73
L	LYS53
L	LEU54
L	HOH713
L	HOH721
L	HOH750

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site_id	AC5
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL H 623

Chain	Residue
H	SER120
H	VAL121
H	TYR122
H	SER215
H	VAL219
H	LYS221
H	HOH775
H	HOH849
L	GLU123

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH

Chain	Residue	Details
L	TYR192-HIS198

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