1RU9

Crystal Structure (A) of u.v.-irradiated cationic cyclization antibody 4C6 Fab at pH 4.6 with a data set collected in-house.

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ACT H 611

Chain	Residue
H	LEU95
H	TRP103
H	HOH712
L	ASN34
L	LEU36

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site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE BEZ H 601

Chain	Residue
H	LEU96
H	PRO230
L	PHE32
L	TRP89
L	GLY91
H	ALA34
H	ASN35
H	TYR50
H	LEU95

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site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL H 621

Chain	Residue
H	LYS44
H	LEU45
L	THR97
L	PHE98
L	HOH624

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site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL L 622

Chain	Residue
H	PHE174
H	PRO175
H	THR186
H	SER188
L	SER176
L	THR178

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site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL H 623

Chain	Residue
H	ARG71
H	ASP72
H	THR73
L	LEU54

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site_id	AC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL H 624

Chain	Residue
H	VAL12
H	GLN16
H	SER17
H	ASP32
H	TYR53
H	TRP97
H	HOH627
H	HOH644

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site_id	AC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL H 625

Chain	Residue
H	VAL121
H	TYR122
H	SER215
H	LYS221
H	HOH666
H	HOH727
L	GLU123

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH

Chain	Residue	Details
L	TYR192-HIS198

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