1RTP

REFINED X-RAY STRUCTURE OF RAT PARVALBUMIN, A MAMMALIAN ALPHA-LINEAGE PARVALBUMIN, AT 2.0 A RESOLUTION

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0005509	molecular_function	calcium ion binding
1	0005737	cellular_component	cytoplasm
1	0010467	biological_process	gene expression
1	0030424	cellular_component	axon
1	0032420	cellular_component	stereocilium
1	0032437	cellular_component	cuticular plate
1	0032991	cellular_component	protein-containing complex
1	0042802	molecular_function	identical protein binding
1	0043025	cellular_component	neuronal cell body
1	0043195	cellular_component	terminal bouton
1	0044877	molecular_function	protein-containing complex binding
1	0046872	molecular_function	metal ion binding
1	0090102	biological_process	cochlea development
1	0098976	biological_process	excitatory chemical synaptic transmission
1	0098977	biological_process	inhibitory chemical synaptic transmission
2	0005509	molecular_function	calcium ion binding
2	0005737	cellular_component	cytoplasm
2	0010467	biological_process	gene expression
2	0030424	cellular_component	axon
2	0032420	cellular_component	stereocilium
2	0032437	cellular_component	cuticular plate
2	0032991	cellular_component	protein-containing complex
2	0042802	molecular_function	identical protein binding
2	0043025	cellular_component	neuronal cell body
2	0043195	cellular_component	terminal bouton
2	0044877	molecular_function	protein-containing complex binding
2	0046872	molecular_function	metal ion binding
2	0090102	biological_process	cochlea development
2	0098976	biological_process	excitatory chemical synaptic transmission
2	0098977	biological_process	inhibitory chemical synaptic transmission
3	0005509	molecular_function	calcium ion binding
3	0005737	cellular_component	cytoplasm
3	0010467	biological_process	gene expression
3	0030424	cellular_component	axon
3	0032420	cellular_component	stereocilium
3	0032437	cellular_component	cuticular plate
3	0032991	cellular_component	protein-containing complex
3	0042802	molecular_function	identical protein binding
3	0043025	cellular_component	neuronal cell body
3	0043195	cellular_component	terminal bouton
3	0044877	molecular_function	protein-containing complex binding
3	0046872	molecular_function	metal ion binding
3	0090102	biological_process	cochlea development
3	0098976	biological_process	excitatory chemical synaptic transmission
3	0098977	biological_process	inhibitory chemical synaptic transmission

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA 1 110

Chain	Residue
1	ASP51
1	ASP53
1	SER55
1	PHE57
1	GLU59
1	GLU62

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA 1 111

Chain	Residue
1	ASP90
1	ASP92
1	ASP94
1	LYS96
1	GLU101
1	HOH121

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA 2 110

Chain	Residue
2	ASP51
2	ASP53
2	SER55
2	PHE57
2	GLU59
2	GLU62

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA 2 111

Chain	Residue
2	ASP90
2	ASP92
2	ASP94
2	LYS96
2	GLU101
2	HOH148

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA 3 110

Chain	Residue
3	ASP51
3	ASP53
3	SER55
3	PHE57
3	GLU59
3	GLU62

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA 3 111

Chain	Residue
3	ASP90
3	ASP92
3	ASP94
3	LYS96
3	GLU101
3	HOH145

---

site_id	CA1
Number of Residues	6
Details

Chain	Residue
1	ASP51
1	ASP53
1	SER55
1	PHE57
1	GLU59
1	GLU62

---

site_id	CA2
Number of Residues	6
Details

Chain	Residue
1	LYS96
1	GLU101
1	HOH121
1	ASP90
1	ASP92
1	ASP94

---

site_id	CB1
Number of Residues	6
Details

Chain	Residue
2	ASP51
2	ASP53
2	SER55
2	PHE57
2	GLU59
2	GLU62

---

site_id	CB2
Number of Residues	6
Details

Chain	Residue
2	ASP90
2	ASP92
2	ASP94
2	LYS96
2	GLU101
1	HOH121

---

site_id	CC1
Number of Residues	6
Details

Chain	Residue
3	ASP51
3	ASP53
3	SER55
3	PHE57
3	GLU59
3	GLU62

---

site_id	CC2
Number of Residues	6
Details

Chain	Residue
3	ASP90
3	ASP92
3	ASP94
3	LYS96
3	GLU101
1	HOH121

---

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DKDKSGFIEedEL

Chain	Residue	Details
1	ASP51-LEU63
1	ASP90-PHE102

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	27
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00448

Chain	Residue	Details
1	LYS52
2	LYS52
2	LYS54
2	GLY56
2	LEU63
2	LYS91
2	GLY93
2	GLY95
2	ILE97
2	PHE102
3	LYS52
1	LYS54
3	LYS54
3	GLY56
3	LEU63
3	LYS91
3	GLY93
3	GLY95
3	ILE97
3	PHE102
1	GLY56
1	LEU63
1	LYS91
1	GLY93
1	GLY95
1	ILE97
1	PHE102

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:22673903

Chain	Residue	Details
1	MET2
3	ALA8
3	PHE24
3	ILE66
1	ALA8
1	PHE24
1	ILE66
2	MET2
2	ALA8
2	PHE24
2	ILE66
3	MET2

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