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1RQ7

MYCOBACTERIUM TUBERCULOSIS FTSZ IN COMPLEX WITH GDP

Functional Information from GO Data
ChainGOidnamespacecontents
A0000287molecular_functionmagnesium ion binding
A0000917biological_processdivision septum assembly
A0000921biological_processseptin ring assembly
A0003924molecular_functionGTPase activity
A0005515molecular_functionprotein binding
A0005525molecular_functionGTP binding
A0005737cellular_componentcytoplasm
A0005886cellular_componentplasma membrane
A0032153cellular_componentcell division site
A0043093biological_processFtsZ-dependent cytokinesis
A0045787biological_processpositive regulation of cell cycle
A0051258biological_processprotein polymerization
A0051301biological_processcell division
A0090529biological_processcell septum assembly
B0000287molecular_functionmagnesium ion binding
B0000917biological_processdivision septum assembly
B0000921biological_processseptin ring assembly
B0003924molecular_functionGTPase activity
B0005515molecular_functionprotein binding
B0005525molecular_functionGTP binding
B0005737cellular_componentcytoplasm
B0005886cellular_componentplasma membrane
B0032153cellular_componentcell division site
B0043093biological_processFtsZ-dependent cytokinesis
B0045787biological_processpositive regulation of cell cycle
B0051258biological_processprotein polymerization
B0051301biological_processcell division
B0090529biological_processcell septum assembly
Functional Information from PDB Data
site_idAC1
Number of Residues23
DetailsBINDING SITE FOR RESIDUE GDP A 380
ChainResidue
AGLY17
AGLY107
APRO132
AGLU136
AARG140
APHE180
AALA183
AASP184
ALEU187
AHOH405
AHOH414
AGLY18
AHOH416
AHOH426
AHOH429
AHOH450
AGLY19
AASN22
AGLY101
AGLU102
AGLY104
AGLY105
ATHR106

Functional Information from PROSITE/UniProt
site_idPS01134
Number of Residues35
DetailsFTSZ_1 FtsZ protein signature 1. NTDaQaLlmsdadvkldvgrdstr.GlGAGAdPevG
ChainResidueDetails
AASN41-GLY75

site_idPS01135
Number of Residues22
DetailsFTSZ_2 FtsZ protein signature 2. DMvFVTAGeGGGTGTGGAPVVA
ChainResidueDetails
AASP94-ALA115

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues10
DetailsBINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00909, ECO:0000269|PubMed:15342249, ECO:0000269|PubMed:23888039
ChainResidueDetails
AGLY18
BASP184
AGLY105
AGLU136
AARG140
AASP184
BGLY18
BGLY105
BGLU136
BARG140

227111

PDB entries from 2024-11-06

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