1RPW
Crystal Structure Of The Multidrug Binding Protein Qacr Bound To The Diamidine Hexamidine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0006351 | biological_process | DNA-templated transcription |
| A | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0006351 | biological_process | DNA-templated transcription |
| B | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| C | 0003677 | molecular_function | DNA binding |
| C | 0003700 | molecular_function | DNA-binding transcription factor activity |
| C | 0006351 | biological_process | DNA-templated transcription |
| C | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003700 | molecular_function | DNA-binding transcription factor activity |
| D | 0006351 | biological_process | DNA-templated transcription |
| D | 0045892 | biological_process | negative regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 189 |
| Chain | Residue |
| B | LYS4 |
| B | HIS42 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 189 |
| Chain | Residue |
| C | THR25 |
| C | TYR40 |
| C | THR45 |
| C | LYS46 |
| C | SO4192 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 D 189 |
| Chain | Residue |
| D | GLU27 |
| D | LYS36 |
| D | THR24 |
| D | GLY26 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 C 190 |
| Chain | Residue |
| A | LYS66 |
| C | ASN2 |
| C | LEU3 |
| C | LYS4 |
| C | ASN38 |
| C | HIS42 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 C 191 |
| Chain | Residue |
| C | THR24 |
| C | GLY26 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 D 190 |
| Chain | Residue |
| D | LYS36 |
| D | TYR40 |
| D | THR45 |
| D | LYS46 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 190 |
| Chain | Residue |
| B | SER35 |
| B | LYS36 |
| D | LYS60 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 192 |
| Chain | Residue |
| C | TYR20 |
| C | LYS46 |
| C | GLU105 |
| C | TYR106 |
| C | SO4189 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 D 191 |
| Chain | Residue |
| D | LYS12 |
| D | ILE53 |
| D | ILE56 |
| D | GLU57 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 D 192 |
| Chain | Residue |
| B | LYS36 |
| B | TYR40 |
| D | ASN2 |
| D | ASP5 |
| D | LYS6 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 189 |
| Chain | Residue |
| A | GLN64 |
| A | TYR91 |
| C | GLN64 |
| C | GLU90 |
| C | TYR91 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 190 |
| Chain | Residue |
| A | THR24 |
| A | THR25 |
| A | LYS46 |
| site_id | BC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 D 193 |
| Chain | Residue |
| D | HIS128 |
| D | LYS132 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 193 |
| Chain | Residue |
| C | GLU13 |
| C | LYS17 |
| C | LYS30 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 191 |
| Chain | Residue |
| B | ASN2 |
| B | LEU3 |
| B | LYS4 |
| B | ASN38 |
| B | HIS42 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 194 |
| Chain | Residue |
| A | LYS73 |
| C | HIS164 |
| C | GLU165 |
| C | GLN166 |
| site_id | BC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 D 194 |
| Chain | Residue |
| C | TYR107 |
| D | HIS164 |
| site_id | BC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 192 |
| Chain | Residue |
| B | ASP144 |
| B | ASN146 |
| B | ALA147 |
| site_id | CC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 D 195 |
| Chain | Residue |
| D | ASN135 |
| D | SER141 |
| D | ILE142 |
| site_id | CC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 D 196 |
| Chain | Residue |
| D | SER187 |
| site_id | CC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE DID B 193 |
| Chain | Residue |
| A | PHE162 |
| B | GLU57 |
| B | TRP61 |
| B | GLN64 |
| B | TYR93 |
| B | GLU120 |
| B | ILE124 |
| B | ASN154 |
| B | ASN157 |
| B | HOH199 |
| B | HOH200 |
Functional Information from PROSITE/UniProt
| site_id | PS01081 |
| Number of Residues | 31 |
| Details | HTH_TETR_1 TetR-type HTH domain signature. GYnatTTgeIvklseSSkGnLYyHFkTKen.L |
| Chain | Residue | Details |
| A | GLY19-LEU49 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 76 |
| Details | DNA binding: {"description":"H-T-H motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU00335","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
