Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0006006 | biological_process | glucose metabolic process |
A | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
A | 0050661 | molecular_function | NADP binding |
A | 0051287 | molecular_function | NAD binding |
B | 0006006 | biological_process | glucose metabolic process |
B | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
B | 0050661 | molecular_function | NADP binding |
B | 0051287 | molecular_function | NAD binding |
O | 0006006 | biological_process | glucose metabolic process |
O | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
O | 0050661 | molecular_function | NADP binding |
O | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE SO4 O 7338 |
Chain | Residue |
O | THR179 |
O | ASP181 |
O | ARG195 |
O | ARG231 |
O | NDP7335 |
O | HOH7367 |
O | HOH7448 |
site_id | AC2 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE SO4 O 7339 |
Chain | Residue |
O | GLY209 |
O | ALA210 |
O | HOH7408 |
O | HOH7471 |
O | HOH7535 |
O | SER148 |
O | THR208 |
site_id | AC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 A 1338 |
Chain | Residue |
A | THR179 |
A | ASP181 |
A | ARG195 |
A | NDP1335 |
A | HOH1402 |
site_id | AC4 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 A 1339 |
Chain | Residue |
A | SER148 |
A | THR150 |
A | THR208 |
A | GLY209 |
A | HOH1422 |
A | HOH1453 |
site_id | AC5 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE SO4 B 2338 |
Chain | Residue |
B | THR179 |
B | ASP181 |
B | ARG195 |
B | ARG231 |
B | NDP2335 |
B | HOH2438 |
B | HOH2472 |
site_id | AC6 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 B 2339 |
Chain | Residue |
B | SER148 |
B | THR150 |
B | THR208 |
B | GLY209 |
B | HOH2433 |
B | HOH2453 |
site_id | AC7 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 A 901 |
Chain | Residue |
A | GLU253 |
A | ASN256 |
A | ARG260 |
site_id | AC8 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE SO4 O 902 |
Chain | Residue |
A | LYS72 |
A | HOH1352 |
O | PHE251 |
O | ALA252 |
O | VAL299 |
O | HOH7370 |
O | HOH7459 |
site_id | AC9 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 A 903 |
Chain | Residue |
A | GLY36 |
A | VAL37 |
A | LYS38 |
A | HOH1374 |
site_id | BC1 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 B 904 |
Chain | Residue |
B | SER247 |
B | LYS248 |
B | LYS249 |
site_id | BC2 |
Number of Residues | 22 |
Details | BINDING SITE FOR RESIDUE NDP O 7335 |
Chain | Residue |
O | GLY9 |
O | ARG10 |
O | ILE11 |
O | THR33 |
O | ARG77 |
O | GLY95 |
O | THR96 |
O | GLY97 |
O | PHE99 |
O | THR119 |
O | ALA120 |
O | ASN313 |
O | SO47338 |
O | HOH7354 |
O | HOH7356 |
O | HOH7357 |
O | HOH7358 |
O | HOH7368 |
O | HOH7450 |
O | HOH7506 |
O | HOH7546 |
O | HOH7548 |
site_id | BC3 |
Number of Residues | 20 |
Details | BINDING SITE FOR RESIDUE NDP A 1335 |
Chain | Residue |
A | GLY9 |
A | ARG10 |
A | ILE11 |
A | THR33 |
A | ARG77 |
A | GLY95 |
A | THR96 |
A | GLY97 |
A | THR119 |
A | ALA120 |
A | ASN313 |
A | TYR317 |
A | SO41338 |
A | HOH1345 |
A | HOH1354 |
A | HOH1356 |
A | HOH1402 |
A | HOH1404 |
A | HOH1444 |
B | HOH2357 |
site_id | BC4 |
Number of Residues | 20 |
Details | BINDING SITE FOR RESIDUE NDP B 2335 |
Chain | Residue |
B | ARG10 |
B | ILE11 |
B | ASN31 |
B | THR33 |
B | ARG77 |
B | THR96 |
B | GLY97 |
B | THR119 |
B | ALA120 |
B | ASN313 |
B | TYR317 |
B | SO42338 |
B | HOH2366 |
B | HOH2375 |
B | HOH2385 |
B | HOH2429 |
B | HOH2470 |
B | HOH2472 |
A | HOH1361 |
B | GLY9 |
Functional Information from PROSITE/UniProt
site_id | PS00071 |
Number of Residues | 8 |
Details | GAPDH Glyceraldehyde 3-phosphate dehydrogenase active site. ASCTTNcL |
Chain | Residue | Details |
O | ALA147-LEU154 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 3 |
Details | ACT_SITE: Nucleophile |
Chain | Residue | Details |
O | CYS149 | |
A | CYS149 | |
B | CYS149 | |
Chain | Residue | Details |
O | ARG10 | |
B | ASP32 | |
B | ARG77 | |
B | ASN313 | |
O | ASP32 | |
O | ARG77 | |
O | ASN313 | |
A | ARG10 | |
A | ASP32 | |
A | ARG77 | |
A | ASN313 | |
B | ARG10 | |
site_id | SWS_FT_FI3 |
Number of Residues | 15 |
Details | BINDING: BINDING => ECO:0000250 |
Chain | Residue | Details |
O | SER148 | |
A | ARG231 | |
B | SER148 | |
B | THR179 | |
B | ARG195 | |
B | THR208 | |
B | ARG231 | |
O | THR179 | |
O | ARG195 | |
O | THR208 | |
O | ARG231 | |
A | SER148 | |
A | THR179 | |
A | ARG195 | |
A | THR208 | |
site_id | SWS_FT_FI4 |
Number of Residues | 3 |
Details | SITE: Activates thiol group during catalysis => ECO:0000250 |
Chain | Residue | Details |
O | HIS176 | |
A | HIS176 | |
B | HIS176 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1szj |
Chain | Residue | Details |
O | CYS149 | |
O | HIS176 | |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1szj |
Chain | Residue | Details |
A | CYS149 | |
A | HIS176 | |
site_id | CSA3 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1szj |
Chain | Residue | Details |
B | CYS149 | |
B | HIS176 | |