1RK9
Solution Structure of Human alpha-Parvalbumin (Minimized Average Structure)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0010467 | biological_process | gene expression |
| A | 0030424 | cellular_component | axon |
| A | 0045202 | cellular_component | synapse |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0098976 | biological_process | excitatory chemical synaptic transmission |
| A | 0098977 | biological_process | inhibitory chemical synaptic transmission |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 111 |
| Chain | Residue |
| A | ASP91 |
| A | ASP93 |
| A | ASP95 |
| A | LYS97 |
| A | GLU102 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 112 |
| Chain | Residue |
| A | GLU60 |
| A | GLU63 |
| A | ASP52 |
| A | ASP54 |
| A | SER56 |
| A | PHE58 |
Functional Information from PROSITE/UniProt
| site_id | PS00018 |
| Number of Residues | 13 |
| Details | EF_HAND_1 EF-hand calcium-binding domain. DKDKSGFIEedEL |
| Chain | Residue | Details |
| A | ASP52-LEU64 | |
| A | ASP91-PHE103 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 35 |
| Details | Domain: {"description":"EF-hand 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 32 |
| Details | Domain: {"description":"EF-hand 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"15122922","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"39584689","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1RJV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1RK9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9BB8","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15122922","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"39584689","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1RJV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1RK9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9BB8","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P02625","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
