1RK2

E. COLI RIBOKINASE COMPLEXED WITH RIBOSE AND ADP, SOLVED IN SPACE GROUP P212121

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004747	molecular_function	ribokinase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006014	biological_process	D-ribose metabolic process
A	0016301	molecular_function	kinase activity
A	0016740	molecular_function	transferase activity
A	0019303	biological_process	D-ribose catabolic process
A	0042803	molecular_function	protein homodimerization activity
A	0044281	biological_process	small molecule metabolic process
A	0046835	biological_process	carbohydrate phosphorylation
A	0046872	molecular_function	metal ion binding
B	0000166	molecular_function	nucleotide binding
B	0004747	molecular_function	ribokinase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006014	biological_process	D-ribose metabolic process
B	0016301	molecular_function	kinase activity
B	0016740	molecular_function	transferase activity
B	0019303	biological_process	D-ribose catabolic process
B	0042803	molecular_function	protein homodimerization activity
B	0044281	biological_process	small molecule metabolic process
B	0046835	biological_process	carbohydrate phosphorylation
B	0046872	molecular_function	metal ion binding
C	0000166	molecular_function	nucleotide binding
C	0004747	molecular_function	ribokinase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006014	biological_process	D-ribose metabolic process
C	0016301	molecular_function	kinase activity
C	0016740	molecular_function	transferase activity
C	0019303	biological_process	D-ribose catabolic process
C	0042803	molecular_function	protein homodimerization activity
C	0044281	biological_process	small molecule metabolic process
C	0046835	biological_process	carbohydrate phosphorylation
C	0046872	molecular_function	metal ion binding
D	0000166	molecular_function	nucleotide binding
D	0004747	molecular_function	ribokinase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006014	biological_process	D-ribose metabolic process
D	0016301	molecular_function	kinase activity
D	0016740	molecular_function	transferase activity
D	0019303	biological_process	D-ribose catabolic process
D	0042803	molecular_function	protein homodimerization activity
D	0044281	biological_process	small molecule metabolic process
D	0046835	biological_process	carbohydrate phosphorylation
D	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00584
Number of Residues	14
Details	PFKB_KINASES_2 pfkB family of carbohydrate kinases signature 2. DTiAAGDtfnGALI

Chain	Residue	Details
A	ASP249-ILE262

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_01987","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11786021","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	60
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01987","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"10438599","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11786021","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9519409","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01987","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11786021","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01987","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"10438599","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11786021","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	a catalytic site defined by CSA, PubMed 9519409

Chain	Residue	Details
A	GLY254

---

site_id	MCSA1
Number of Residues	4
Details	M-CSA 663

Chain	Residue	Details
A	ALA252	electrostatic stabiliser, polar interaction
A	ALA253	electrostatic stabiliser, polar interaction
A	GLY254	electrostatic stabiliser, polar interaction
A	ASP255	electrostatic stabiliser, proton acceptor, proton donor

---

site_id	MCSA2
Number of Residues	4
Details	M-CSA 663

Chain	Residue	Details
B	ALA252	electrostatic stabiliser, polar interaction
B	ALA253	electrostatic stabiliser, polar interaction
B	GLY254	electrostatic stabiliser, polar interaction
B	ASP255	electrostatic stabiliser, proton acceptor, proton donor

---

site_id	MCSA3
Number of Residues	4
Details	M-CSA 663

Chain	Residue	Details
C	ALA252	electrostatic stabiliser, polar interaction
C	ALA253	electrostatic stabiliser, polar interaction
C	GLY254	electrostatic stabiliser, polar interaction
C	ASP255	electrostatic stabiliser, proton acceptor, proton donor

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site_id	MCSA4
Number of Residues	4
Details	M-CSA 663

Chain	Residue	Details
D	ALA252	electrostatic stabiliser, polar interaction
D	ALA253	electrostatic stabiliser, polar interaction
D	GLY254	electrostatic stabiliser, polar interaction
D	ASP255	electrostatic stabiliser, proton acceptor, proton donor

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