Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000105 | biological_process | L-histidine biosynthetic process |
| A | 0004424 | molecular_function | imidazoleglycerol-phosphate dehydratase activity |
| B | 0000105 | biological_process | L-histidine biosynthetic process |
| B | 0004424 | molecular_function | imidazoleglycerol-phosphate dehydratase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE HG A 5503 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE HG B 9503 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EMC A 5501 |
| Chain | Residue |
| A | PHE122 |
| A | CYS124 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EMC A 5502 |
| Chain | Residue |
| A | HOH5589 |
| A | THR38 |
| A | CYS62 |
| A | CYS77 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EMC B 9501 |
| Chain | Residue |
| B | PHE122 |
| B | CYS124 |
| B | SER142 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EMC B 9502 |
| Chain | Residue |
| B | THR38 |
| B | CYS62 |
| B | THR73 |
| B | CYS77 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 301 |
| Chain | Residue |
| A | LYS52 |
| A | HIS53 |
| A | ARG97 |
| A | LYS175 |
| A | HOH5504 |
| A | HOH5585 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 302 |
| Chain | Residue |
| B | HIS53 |
| B | ARG97 |
| B | LYS175 |
| B | HOH9504 |
| B | HOH9593 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 303 |
| Chain | Residue |
| A | GLU164 |
| A | HOH5576 |
| B | ASN165 |
| B | ASN166 |
| B | HIS167 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 304 |
| Chain | Residue |
| A | ASN165 |
| A | ASN166 |
| A | HIS167 |
| A | HOH5560 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 305 |
| Chain | Residue |
| A | ASN35 |
| A | VAL36 |
| A | GLN61 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACY B 311 |
| Chain | Residue |
| A | GLU139 |
| A | HIS143 |
| B | ARG119 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACY B 312 |
| Chain | Residue |
| B | HIS16 |
| B | HOH9616 |
| B | HOH9623 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACY B 313 |
| Chain | Residue |
| B | LYS93 |
| B | GLY94 |
| B | HOH9581 |
| site_id | BC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACY B 314 |
| Chain | Residue |
| B | ARG162 |
| B | GOL325 |
| B | HOH9541 |
| B | HOH9591 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACY B 315 |
| Chain | Residue |
| B | SER7 |
| B | SER18 |
| B | THR20 |
| B | HOH9554 |
| B | HOH9590 |
| site_id | BC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACY B 316 |
| Chain | Residue |
| B | THR48 |
| B | HOH9551 |
| site_id | BC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACY B 317 |
| Chain | Residue |
| B | LYS52 |
| B | HOH9581 |
| B | HOH9593 |
| site_id | CC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 321 |
| Chain | Residue |
| B | GLY134 |
| B | HIS167 |
| B | HOH9572 |
| site_id | CC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 322 |
| Chain | Residue |
| B | ARG92 |
| B | SER118 |
| B | HOH9565 |
| B | HOH9596 |
| site_id | CC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 323 |
| Chain | Residue |
| B | LYS96 |
| B | MET183 |
| B | GOL324 |
| B | HOH9514 |
| B | HOH9576 |
| B | HOH9609 |
| B | HOH9628 |
| B | HOH9629 |
| site_id | CC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 324 |
| Chain | Residue |
| B | GOL323 |
| B | HOH9627 |
| B | HOH9629 |
| B | HOH9630 |
| B | HOH9630 |
| B | HOH9630 |
| B | HOH9631 |
| site_id | CC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 325 |
| Chain | Residue |
| B | ACY314 |
| B | HOH9610 |
| B | HOH9610 |
| B | HOH9610 |
| B | HOH9611 |
| site_id | CC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 327 |
| Chain | Residue |
| B | ILE5 |
| B | SER7 |
| B | HOH9549 |
| B | HOH9570 |
| B | HOH9597 |
| B | HOH9619 |
Functional Information from PROSITE/UniProt
| site_id | PS00954 |
| Number of Residues | 14 |
| Details | IGP_DEHYDRATASE_1 Imidazoleglycerol-phosphate dehydratase signature 1. IDdHHtaEdcALAL |
| Chain | Residue | Details |
| A | ILE68-LEU81 | |
| site_id | PS00955 |
| Number of Residues | 13 |
| Details | IGP_DEHYDRATASE_2 Imidazoleglycerol-phosphate dehydratase signature 2. GeNnHHiaESaFK |
| Chain | Residue | Details |
| A | GLY163-LYS175 | |
1RHY
