1RCQ

The 1.45 A crystal structure of alanine racemase from a pathogenic bacterium, Pseudomonas aeruginosa, contains both internal and external aldimine forms

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0005829	cellular_component	cytosol
A	0006522	biological_process	alanine metabolic process
A	0008784	molecular_function	alanine racemase activity
A	0016853	molecular_function	isomerase activity
A	0030170	molecular_function	pyridoxal phosphate binding
A	0030632	biological_process	D-alanine biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	BINDING SITE FOR RESIDUE PLP A 358

Chain	Residue
A	VAL31
A	ARG208
A	GLY210
A	ILE211
A	TYR341
A	DLY359
A	HOH531
A	HOH603
A	LYS33
A	TYR37
A	KCX122
A	ARG129
A	HIS158
A	ASN192
A	SER193
A	PRO194

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site_id	AC2
Number of Residues	14
Details	BINDING SITE FOR RESIDUE DLY A 359

Chain	Residue
A	LYS33
A	TYR37
A	ARG129
A	TYR253
A	TYR272
A	SER300
A	MET301
A	ASP302
A	MET303
A	TYR341
A	PLP358
A	HOH518
A	HOH601
A	HOH603

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Functional Information from PROSITE/UniProt

site_id	PS00395
Number of Residues	11
Details	ALANINE_RACEMASE Alanine racemase pyridoxal-phosphate attachment site. AViKADAYGHG

Chain	Residue	Details
A	ALA30-GLY40

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor; specific for D-alanine => ECO:0000255|HAMAP-Rule:MF_01201

Chain	Residue	Details
A	LYS33

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: Proton acceptor; specific for L-alanine => ECO:0000255|HAMAP-Rule:MF_01201

Chain	Residue	Details
A	TYR253

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000305|PubMed:14674749

Chain	Residue	Details
A	ARG129

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01201

Chain	Residue	Details
A	MET301

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: N6-(pyridoxal phosphate)lysine => ECO:0000269|PubMed:14674749

Chain	Residue	Details
A	LYS33

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: N6-carboxylysine => ECO:0000269|PubMed:14674749

Chain	Residue	Details
A	KCX122

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1bd0

Chain	Residue	Details
A	LYS33
A	ARG129

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