Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1RCO

SPINACH RUBISCO IN COMPLEX WITH THE INHIBITOR D-XYLULOSE-2,2-DIOL-1,5-BISPHOSPHATE

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0000287	molecular_function	magnesium ion binding
B	0009507	cellular_component	chloroplast
B	0015977	biological_process	carbon fixation
B	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
B	0019253	biological_process	reductive pentose-phosphate cycle
C	0009507	cellular_component	chloroplast
C	0015977	biological_process	carbon fixation
C	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
C	0019253	biological_process	reductive pentose-phosphate cycle
E	0000287	molecular_function	magnesium ion binding
E	0009507	cellular_component	chloroplast
E	0015977	biological_process	carbon fixation
E	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
E	0019253	biological_process	reductive pentose-phosphate cycle
F	0009507	cellular_component	chloroplast
F	0015977	biological_process	carbon fixation
F	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
F	0019253	biological_process	reductive pentose-phosphate cycle
H	0000287	molecular_function	magnesium ion binding
H	0009507	cellular_component	chloroplast
H	0015977	biological_process	carbon fixation
H	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
H	0019253	biological_process	reductive pentose-phosphate cycle
I	0009507	cellular_component	chloroplast
I	0015977	biological_process	carbon fixation
I	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
I	0019253	biological_process	reductive pentose-phosphate cycle
K	0000287	molecular_function	magnesium ion binding
K	0009507	cellular_component	chloroplast
K	0015977	biological_process	carbon fixation
K	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
K	0019253	biological_process	reductive pentose-phosphate cycle
L	0000287	molecular_function	magnesium ion binding
L	0009507	cellular_component	chloroplast
L	0015977	biological_process	carbon fixation
L	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
L	0019253	biological_process	reductive pentose-phosphate cycle
M	0009507	cellular_component	chloroplast
M	0015977	biological_process	carbon fixation
M	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
M	0019253	biological_process	reductive pentose-phosphate cycle
O	0000287	molecular_function	magnesium ion binding
O	0009507	cellular_component	chloroplast
O	0015977	biological_process	carbon fixation
O	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
O	0019253	biological_process	reductive pentose-phosphate cycle
P	0009507	cellular_component	chloroplast
P	0015977	biological_process	carbon fixation
P	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
P	0019253	biological_process	reductive pentose-phosphate cycle
R	0000287	molecular_function	magnesium ion binding
R	0009507	cellular_component	chloroplast
R	0015977	biological_process	carbon fixation
R	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
R	0019253	biological_process	reductive pentose-phosphate cycle
S	0009507	cellular_component	chloroplast
S	0015977	biological_process	carbon fixation
S	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
S	0019253	biological_process	reductive pentose-phosphate cycle
T	0009507	cellular_component	chloroplast
T	0015977	biological_process	carbon fixation
T	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
T	0019253	biological_process	reductive pentose-phosphate cycle
V	0000287	molecular_function	magnesium ion binding
V	0009507	cellular_component	chloroplast
V	0015977	biological_process	carbon fixation
V	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
V	0019253	biological_process	reductive pentose-phosphate cycle
W	0009507	cellular_component	chloroplast
W	0015977	biological_process	carbon fixation
W	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
W	0019253	biological_process	reductive pentose-phosphate cycle

Functional Information from PDB Data

site_id	AC1
Number of Residues	25
Details	BINDING SITE FOR RESIDUE XDP L 476

Chain	Residue
B	GLU60
B	THR65
B	TRP66
B	ASN123
B	HOH477
L	LYS175
L	LYS177
L	ASP203
L	GLU204
L	ARG295
L	HIS327
L	LYS334
L	LEU335
L	SER379
L	GLY380
L	GLY381
L	GLY403
L	GLY404
L	HOH496
L	HOH504
L	HOH507
L	HOH521
L	HOH564
L	HOH579
L	HOH585

site_id	AC2
Number of Residues	25
Details	BINDING SITE FOR RESIDUE XDP B 476

Chain	Residue
B	LYS175
B	LYS177
B	ASP203
B	GLU204
B	ARG295
B	HIS327
B	LYS334
B	LEU335
B	SER379
B	GLY380
B	GLY381
B	GLY403
B	GLY404
B	HOH503
B	HOH510
B	HOH513
B	HOH526
B	HOH568
B	HOH583
B	HOH589
L	GLU60
L	THR65
L	TRP66
L	ASN123
L	HOH654

site_id	AC3
Number of Residues	25
Details	BINDING SITE FOR RESIDUE XDP E 476

Chain	Residue
E	LYS175
E	LYS177
E	ASP203
E	GLU204
E	ARG295
E	HIS327
E	LYS334
E	LEU335
E	SER379
E	GLY380
E	GLY381
E	GLY403
E	GLY404
E	HOH504
E	HOH511
E	HOH514
E	HOH528
E	HOH572
E	HOH587
E	HOH593
H	GLU60
H	THR65
H	TRP66
H	ASN123
H	HOH483

site_id	AC4
Number of Residues	25
Details	BINDING SITE FOR RESIDUE XDP H 476

Chain	Residue
E	GLU60
E	THR65
E	TRP66
E	ASN123
E	HOH660
H	LYS175
H	LYS177
H	ASP203
H	GLU204
H	ARG295
H	HIS327
H	LYS334
H	LEU335
H	SER379
H	GLY380
H	GLY381
H	GLY403
H	GLY404
H	HOH510
H	HOH518
H	HOH521
H	HOH535
H	HOH579
H	HOH594
H	HOH600

site_id	AC5
Number of Residues	25
Details	BINDING SITE FOR RESIDUE XDP K 476

Chain	Residue
K	LYS175
K	LYS177
K	ASP203
K	GLU204
K	ARG295
K	HIS327
K	LYS334
K	LEU335
K	SER379
K	GLY380
K	GLY381
K	GLY403
K	GLY404
K	HOH976
K	HOH987
K	HOH991
K	HOH1010
K	HOH1063
K	HOH1087
K	HOH1096
O	GLU60
O	THR65
O	TRP66
O	ASN123
O	HOH953

site_id	AC6
Number of Residues	25
Details	BINDING SITE FOR RESIDUE XDP O 476

Chain	Residue
K	GLU60
K	THR65
K	TRP66
K	ASN123
K	HOH1191
O	LYS175
O	LYS177
O	ASP203
O	GLU204
O	ARG295
O	HIS327
O	LYS334
O	LEU335
O	SER379
O	GLY380
O	GLY381
O	GLY403
O	GLY404
O	HOH1214
O	HOH1225
O	HOH1229
O	HOH1248
O	HOH1301
O	HOH1325
O	HOH1334

site_id	AC7
Number of Residues	25
Details	BINDING SITE FOR RESIDUE XDP R 476

Chain	Residue
R	LYS175
R	LYS177
R	ASP203
R	GLU204
R	ARG295
R	HIS327
R	LYS334
R	LEU335
R	SER379
R	GLY380
R	GLY381
R	GLY403
R	GLY404
R	HOH509
R	HOH516
R	HOH519
R	HOH533
R	HOH577
R	HOH592
R	HOH598
V	GLU60
V	THR65
V	TRP66
V	ASN123
V	HOH490

site_id	AC8
Number of Residues	24
Details	BINDING SITE FOR RESIDUE XDP V 476

Chain	Residue
R	GLU60
R	THR65
R	TRP66
V	LYS175
V	LYS177
V	ASP203
V	GLU204
V	ARG295
V	HIS327
V	LYS334
V	LEU335
V	SER379
V	GLY380
V	GLY381
V	GLY403
V	GLY404
V	HOH498
V	HOH518
V	HOH526
V	HOH529
V	HOH544
V	HOH586
V	HOH602
V	HOH608

site_id	ACB
Number of Residues	3
Details	ACTIVE SITE.

Chain	Residue
B	LYS201
B	ASP203
L	GLU204

site_id	ACE
Number of Residues	3
Details	ACTIVE SITE.

Chain	Residue
E	LYS201
E	ASP203
L	GLU204

site_id	ACH
Number of Residues	3
Details	ACTIVE SITE.

Chain	Residue
H	LYS201
H	ASP203
L	GLU204

site_id	ACK
Number of Residues	3
Details	ACTIVE SITE.

Chain	Residue
K	LYS201
K	ASP203
L	GLU204

site_id	ACL
Number of Residues	3
Details	ACTIVE SITE.

Chain	Residue
L	LYS201
L	ASP203
L	GLU204

site_id	ACO
Number of Residues	3
Details	ACTIVE SITE.

Chain	Residue
O	LYS201
O	ASP203
L	GLU204

site_id	ACR
Number of Residues	3
Details	ACTIVE SITE.

Chain	Residue
R	LYS201
R	ASP203
L	GLU204

site_id	ACV
Number of Residues	3
Details	ACTIVE SITE.

Chain	Residue
V	LYS201
V	ASP203
L	GLU204

Functional Information from PROSITE/UniProt

site_id	PS00157
Number of Residues	9
Details	RUBISCO_LARGE Ribulose bisphosphate carboxylase large chain active site. GlDFtKdDE

Chain	Residue	Details
L	GLY196-GLU204

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"2118958","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"637859","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9092835","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	8
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"637859","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	40
Details	Binding site: {"evidences":[{"source":"PubMed","id":"9034362","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1RCX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	8
Details	Binding site: {"description":"in homodimeric partner","evidences":[{"source":"PubMed","id":"9034362","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1RCX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	24
Details	Binding site: {}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	8
Details	Binding site: {"description":"via carbamate group","evidences":[{"source":"PubMed","id":"8648644","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9092835","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14596800","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"2118958","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"9034362","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"8648644","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9092835","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14596800","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"2118958","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"9034362","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"9034362","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1RXO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PubMed","id":"9034362","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1RCX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1RXO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	8
Details	Site: {"description":"Not N6-methylated","evidences":[{"source":"PubMed","id":"2928307","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	8
Details	Site: {"description":"Transition state stabilizer","evidences":[{"source":"PubMed","id":"8955130","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI12
Number of Residues	8
Details	Modified residue: {"description":"N6-carboxylysine","evidences":[{"source":"PubMed","id":"14596800","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"2118958","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8648644","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9034362","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9092835","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI13
Number of Residues	8
Details	Modified residue: {"description":"Methionine derivative"}

Chain

Residue

Details

Catalytic Information from CSA

site_id	CSA1
Number of Residues	6
Details	Annotated By Reference To The Literature 1rbl

Chain	Residue	Details
L	LYS175
L	LYS201
L	LYS177
L	HIS294
L	ASP203
L	HIS327

site_id	CSA2
Number of Residues	6
Details	Annotated By Reference To The Literature 1rbl

Chain	Residue	Details
B	LYS175
B	LYS201
B	LYS177
B	HIS294
B	ASP203
B	HIS327

site_id	CSA3
Number of Residues	6
Details	Annotated By Reference To The Literature 1rbl

Chain	Residue	Details
E	LYS175
E	LYS201
E	LYS177
E	HIS294
E	ASP203
E	HIS327

site_id	CSA4
Number of Residues	6
Details	Annotated By Reference To The Literature 1rbl

Chain	Residue	Details
H	LYS175
H	LYS201
H	LYS177
H	HIS294
H	ASP203
H	HIS327

site_id	CSA5
Number of Residues	6
Details	Annotated By Reference To The Literature 1rbl

Chain	Residue	Details
K	LYS175
K	LYS201
K	LYS177
K	HIS294
K	ASP203
K	HIS327

site_id	CSA6
Number of Residues	6
Details	Annotated By Reference To The Literature 1rbl

Chain	Residue	Details
O	LYS175
O	LYS201
O	LYS177
O	HIS294
O	ASP203
O	HIS327

site_id	CSA7
Number of Residues	6
Details	Annotated By Reference To The Literature 1rbl

Chain	Residue	Details
R	LYS175
R	LYS201
R	LYS177
R	HIS294
R	ASP203
R	HIS327

site_id	CSA8
Number of Residues	6
Details	Annotated By Reference To The Literature 1rbl

Chain	Residue	Details
V	LYS175
V	LYS201
V	LYS177
V	HIS294
V	ASP203
V	HIS327

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)