Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1RCO

SPINACH RUBISCO IN COMPLEX WITH THE INHIBITOR D-XYLULOSE-2,2-DIOL-1,5-BISPHOSPHATE

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0000287	molecular_function	magnesium ion binding
B	0004497	molecular_function	monooxygenase activity
B	0009507	cellular_component	chloroplast
B	0009853	biological_process	photorespiration
B	0015977	biological_process	carbon fixation
B	0015979	biological_process	photosynthesis
B	0016829	molecular_function	lyase activity
B	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
B	0019253	biological_process	reductive pentose-phosphate cycle
B	0046872	molecular_function	metal ion binding
C	0009507	cellular_component	chloroplast
C	0009853	biological_process	photorespiration
C	0015977	biological_process	carbon fixation
C	0015979	biological_process	photosynthesis
C	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
C	0019253	biological_process	reductive pentose-phosphate cycle
E	0000287	molecular_function	magnesium ion binding
E	0004497	molecular_function	monooxygenase activity
E	0009507	cellular_component	chloroplast
E	0009853	biological_process	photorespiration
E	0015977	biological_process	carbon fixation
E	0015979	biological_process	photosynthesis
E	0016829	molecular_function	lyase activity
E	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
E	0019253	biological_process	reductive pentose-phosphate cycle
E	0046872	molecular_function	metal ion binding
F	0009507	cellular_component	chloroplast
F	0009853	biological_process	photorespiration
F	0015977	biological_process	carbon fixation
F	0015979	biological_process	photosynthesis
F	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
F	0019253	biological_process	reductive pentose-phosphate cycle
H	0000287	molecular_function	magnesium ion binding
H	0004497	molecular_function	monooxygenase activity
H	0009507	cellular_component	chloroplast
H	0009853	biological_process	photorespiration
H	0015977	biological_process	carbon fixation
H	0015979	biological_process	photosynthesis
H	0016829	molecular_function	lyase activity
H	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
H	0019253	biological_process	reductive pentose-phosphate cycle
H	0046872	molecular_function	metal ion binding
I	0009507	cellular_component	chloroplast
I	0009853	biological_process	photorespiration
I	0015977	biological_process	carbon fixation
I	0015979	biological_process	photosynthesis
I	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
I	0019253	biological_process	reductive pentose-phosphate cycle
K	0000287	molecular_function	magnesium ion binding
K	0004497	molecular_function	monooxygenase activity
K	0009507	cellular_component	chloroplast
K	0009853	biological_process	photorespiration
K	0015977	biological_process	carbon fixation
K	0015979	biological_process	photosynthesis
K	0016829	molecular_function	lyase activity
K	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
K	0019253	biological_process	reductive pentose-phosphate cycle
K	0046872	molecular_function	metal ion binding
L	0000287	molecular_function	magnesium ion binding
L	0004497	molecular_function	monooxygenase activity
L	0009507	cellular_component	chloroplast
L	0009853	biological_process	photorespiration
L	0015977	biological_process	carbon fixation
L	0015979	biological_process	photosynthesis
L	0016829	molecular_function	lyase activity
L	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
L	0019253	biological_process	reductive pentose-phosphate cycle
L	0046872	molecular_function	metal ion binding
M	0009507	cellular_component	chloroplast
M	0009853	biological_process	photorespiration
M	0015977	biological_process	carbon fixation
M	0015979	biological_process	photosynthesis
M	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
M	0019253	biological_process	reductive pentose-phosphate cycle
O	0000287	molecular_function	magnesium ion binding
O	0004497	molecular_function	monooxygenase activity
O	0009507	cellular_component	chloroplast
O	0009853	biological_process	photorespiration
O	0015977	biological_process	carbon fixation
O	0015979	biological_process	photosynthesis
O	0016829	molecular_function	lyase activity
O	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
O	0019253	biological_process	reductive pentose-phosphate cycle
O	0046872	molecular_function	metal ion binding
P	0009507	cellular_component	chloroplast
P	0009853	biological_process	photorespiration
P	0015977	biological_process	carbon fixation
P	0015979	biological_process	photosynthesis
P	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
P	0019253	biological_process	reductive pentose-phosphate cycle
R	0000287	molecular_function	magnesium ion binding
R	0004497	molecular_function	monooxygenase activity
R	0009507	cellular_component	chloroplast
R	0009853	biological_process	photorespiration
R	0015977	biological_process	carbon fixation
R	0015979	biological_process	photosynthesis
R	0016829	molecular_function	lyase activity
R	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
R	0019253	biological_process	reductive pentose-phosphate cycle
R	0046872	molecular_function	metal ion binding
S	0009507	cellular_component	chloroplast
S	0009853	biological_process	photorespiration
S	0015977	biological_process	carbon fixation
S	0015979	biological_process	photosynthesis
S	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
S	0019253	biological_process	reductive pentose-phosphate cycle
T	0009507	cellular_component	chloroplast
T	0009853	biological_process	photorespiration
T	0015977	biological_process	carbon fixation
T	0015979	biological_process	photosynthesis
T	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
T	0019253	biological_process	reductive pentose-phosphate cycle
V	0000287	molecular_function	magnesium ion binding
V	0004497	molecular_function	monooxygenase activity
V	0009507	cellular_component	chloroplast
V	0009853	biological_process	photorespiration
V	0015977	biological_process	carbon fixation
V	0015979	biological_process	photosynthesis
V	0016829	molecular_function	lyase activity
V	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
V	0019253	biological_process	reductive pentose-phosphate cycle
V	0046872	molecular_function	metal ion binding
W	0009507	cellular_component	chloroplast
W	0009853	biological_process	photorespiration
W	0015977	biological_process	carbon fixation
W	0015979	biological_process	photosynthesis
W	0016984	molecular_function	ribulose-bisphosphate carboxylase activity
W	0019253	biological_process	reductive pentose-phosphate cycle

Functional Information from PDB Data

site_id	AC1
Number of Residues	25
Details	BINDING SITE FOR RESIDUE XDP L 476

Chain	Residue
B	GLU60
B	THR65
B	TRP66
B	ASN123
B	HOH477
L	LYS175
L	LYS177
L	ASP203
L	GLU204
L	ARG295
L	HIS327
L	LYS334
L	LEU335
L	SER379
L	GLY380
L	GLY381
L	GLY403
L	GLY404
L	HOH496
L	HOH504
L	HOH507
L	HOH521
L	HOH564
L	HOH579
L	HOH585

site_id	AC2
Number of Residues	25
Details	BINDING SITE FOR RESIDUE XDP B 476

Chain	Residue
B	LYS175
B	LYS177
B	ASP203
B	GLU204
B	ARG295
B	HIS327
B	LYS334
B	LEU335
B	SER379
B	GLY380
B	GLY381
B	GLY403
B	GLY404
B	HOH503
B	HOH510
B	HOH513
B	HOH526
B	HOH568
B	HOH583
B	HOH589
L	GLU60
L	THR65
L	TRP66
L	ASN123
L	HOH654

site_id	AC3
Number of Residues	25
Details	BINDING SITE FOR RESIDUE XDP E 476

Chain	Residue
E	LYS175
E	LYS177
E	ASP203
E	GLU204
E	ARG295
E	HIS327
E	LYS334
E	LEU335
E	SER379
E	GLY380
E	GLY381
E	GLY403
E	GLY404
E	HOH504
E	HOH511
E	HOH514
E	HOH528
E	HOH572
E	HOH587
E	HOH593
H	GLU60
H	THR65
H	TRP66
H	ASN123
H	HOH483

site_id	AC4
Number of Residues	25
Details	BINDING SITE FOR RESIDUE XDP H 476

Chain	Residue
E	GLU60
E	THR65
E	TRP66
E	ASN123
E	HOH660
H	LYS175
H	LYS177
H	ASP203
H	GLU204
H	ARG295
H	HIS327
H	LYS334
H	LEU335
H	SER379
H	GLY380
H	GLY381
H	GLY403
H	GLY404
H	HOH510
H	HOH518
H	HOH521
H	HOH535
H	HOH579
H	HOH594
H	HOH600

site_id	AC5
Number of Residues	25
Details	BINDING SITE FOR RESIDUE XDP K 476

Chain	Residue
K	LYS175
K	LYS177
K	ASP203
K	GLU204
K	ARG295
K	HIS327
K	LYS334
K	LEU335
K	SER379
K	GLY380
K	GLY381
K	GLY403
K	GLY404
K	HOH976
K	HOH987
K	HOH991
K	HOH1010
K	HOH1063
K	HOH1087
K	HOH1096
O	GLU60
O	THR65
O	TRP66
O	ASN123
O	HOH953

site_id	AC6
Number of Residues	25
Details	BINDING SITE FOR RESIDUE XDP O 476

Chain	Residue
K	GLU60
K	THR65
K	TRP66
K	ASN123
K	HOH1191
O	LYS175
O	LYS177
O	ASP203
O	GLU204
O	ARG295
O	HIS327
O	LYS334
O	LEU335
O	SER379
O	GLY380
O	GLY381
O	GLY403
O	GLY404
O	HOH1214
O	HOH1225
O	HOH1229
O	HOH1248
O	HOH1301
O	HOH1325
O	HOH1334

site_id	AC7
Number of Residues	25
Details	BINDING SITE FOR RESIDUE XDP R 476

Chain	Residue
R	LYS175
R	LYS177
R	ASP203
R	GLU204
R	ARG295
R	HIS327
R	LYS334
R	LEU335
R	SER379
R	GLY380
R	GLY381
R	GLY403
R	GLY404
R	HOH509
R	HOH516
R	HOH519
R	HOH533
R	HOH577
R	HOH592
R	HOH598
V	GLU60
V	THR65
V	TRP66
V	ASN123
V	HOH490

site_id	AC8
Number of Residues	24
Details	BINDING SITE FOR RESIDUE XDP V 476

Chain	Residue
R	GLU60
R	THR65
R	TRP66
V	LYS175
V	LYS177
V	ASP203
V	GLU204
V	ARG295
V	HIS327
V	LYS334
V	LEU335
V	SER379
V	GLY380
V	GLY381
V	GLY403
V	GLY404
V	HOH498
V	HOH518
V	HOH526
V	HOH529
V	HOH544
V	HOH586
V	HOH602
V	HOH608

site_id	ACB
Number of Residues	3
Details	ACTIVE SITE.

Chain	Residue
B	LYS201
B	ASP203
L	GLU204

site_id	ACE
Number of Residues	3
Details	ACTIVE SITE.

Chain	Residue
E	LYS201
E	ASP203
L	GLU204

site_id	ACH
Number of Residues	3
Details	ACTIVE SITE.

Chain	Residue
H	LYS201
H	ASP203
L	GLU204

site_id	ACK
Number of Residues	3
Details	ACTIVE SITE.

Chain	Residue
K	LYS201
K	ASP203
L	GLU204

site_id	ACL
Number of Residues	3
Details	ACTIVE SITE.

Chain	Residue
L	LYS201
L	ASP203
L	GLU204

site_id	ACO
Number of Residues	3
Details	ACTIVE SITE.

Chain	Residue
O	LYS201
O	ASP203
L	GLU204

site_id	ACR
Number of Residues	3
Details	ACTIVE SITE.

Chain	Residue
R	LYS201
R	ASP203
L	GLU204

site_id	ACV
Number of Residues	3
Details	ACTIVE SITE.

Chain	Residue
V	LYS201
V	ASP203
L	GLU204

Functional Information from PROSITE/UniProt

site_id	PS00157
Number of Residues	9
Details	RUBISCO_LARGE Ribulose bisphosphate carboxylase large chain active site. GlDFtKdDE

Chain	Residue	Details
L	GLY196-GLU204

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	ACT_SITE: Proton acceptor => ECO:0000269\|PubMed:2118958, ECO:0000269\|PubMed:637859, ECO:0000305\|PubMed:9092835

Chain	Residue	Details
L	LYS175
B	LYS175
E	LYS175
H	LYS175
K	LYS175
O	LYS175
R	LYS175
V	LYS175

site_id	SWS_FT_FI2
Number of Residues	8
Details	ACT_SITE: Proton acceptor => ECO:0000269\|PubMed:637859

Chain	Residue	Details
L	HIS294
B	HIS294
E	HIS294
H	HIS294
K	HIS294
O	HIS294
R	HIS294
V	HIS294

site_id	SWS_FT_FI3
Number of Residues	40
Details	BINDING: BINDING => ECO:0000269\|PubMed:9034362, ECO:0007744\|PDB:1RCX

Chain	Residue	Details
L	THR65
B	LYS334
E	THR65
E	GLU204
E	HIS294
E	HIS327
E	LYS334
H	THR65
H	GLU204
H	HIS294
H	HIS327
L	GLU204
H	LYS334
K	THR65
K	GLU204
K	HIS294
K	HIS327
K	LYS334
O	THR65
O	GLU204
O	HIS294
O	HIS327
L	HIS294
O	LYS334
R	THR65
R	GLU204
R	HIS294
R	HIS327
R	LYS334
V	THR65
V	GLU204
V	HIS294
V	HIS327
L	HIS327
V	LYS334
L	LYS334
B	THR65
B	GLU204
B	HIS294
B	HIS327

site_id	SWS_FT_FI4
Number of Residues	8
Details	BINDING: in homodimeric partner => ECO:0000269\|PubMed:9034362, ECO:0007744\|PDB:1RCX

Chain	Residue	Details
L	ASN123
B	ASN123
E	ASN123
H	ASN123
K	ASN123
O	ASN123
R	ASN123
V	ASN123

site_id	SWS_FT_FI5
Number of Residues	24
Details	BINDING:

Chain	Residue	Details
L	THR173
H	THR173
H	LYS177
H	SER379
K	THR173
K	LYS177
K	SER379
O	THR173
O	LYS177
O	SER379
R	THR173
L	LYS177
R	LYS177
R	SER379
V	THR173
V	LYS177
V	SER379
L	SER379
B	THR173
B	LYS177
B	SER379
E	THR173
E	LYS177
E	SER379

site_id	SWS_FT_FI6
Number of Residues	8
Details	BINDING: via carbamate group => ECO:0000269\|PubMed:8648644, ECO:0000269\|PubMed:9092835, ECO:0000305\|PubMed:14596800, ECO:0000305\|PubMed:2118958, ECO:0000305\|PubMed:9034362

Chain	Residue	Details
L	LYS201
B	LYS201
E	LYS201
H	LYS201
K	LYS201
O	LYS201
R	LYS201
V	LYS201

site_id	SWS_FT_FI7
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269\|PubMed:8648644, ECO:0000269\|PubMed:9092835, ECO:0000305\|PubMed:14596800, ECO:0000305\|PubMed:2118958, ECO:0000305\|PubMed:9034362

Chain	Residue	Details
L	ASP203
B	ASP203
E	ASP203
H	ASP203
K	ASP203
O	ASP203
R	ASP203
V	ASP203

site_id	SWS_FT_FI8
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269\|PubMed:9034362, ECO:0007744\|PDB:1RXO

Chain	Residue	Details
L	ARG295
B	ARG295
E	ARG295
H	ARG295
K	ARG295
O	ARG295
R	ARG295
V	ARG295

site_id	SWS_FT_FI9
Number of Residues	24
Details	BINDING: BINDING => ECO:0000269\|PubMed:9034362, ECO:0007744\|PDB:1RCX, ECO:0007744\|PDB:1RXO

Chain	Residue	Details
L	GLY381
H	GLY381
H	GLY403
H	GLY404
K	GLY381
K	GLY403
K	GLY404
O	GLY381
O	GLY403
O	GLY404
R	GLY381
L	GLY403
R	GLY403
R	GLY404
V	GLY381
V	GLY403
V	GLY404
L	GLY404
B	GLY381
B	GLY403
B	GLY404
E	GLY381
E	GLY403
E	GLY404

site_id	SWS_FT_FI10
Number of Residues	8
Details	SITE: Not N6-methylated => ECO:0000269\|PubMed:2928307

Chain	Residue	Details
L	LYS14
B	LYS14
E	LYS14
H	LYS14
K	LYS14
O	LYS14
R	LYS14
V	LYS14

site_id	SWS_FT_FI11
Number of Residues	8
Details	SITE: Transition state stabilizer => ECO:0000305\|PubMed:8955130

Chain	Residue	Details
L	LYS334
B	LYS334
E	LYS334
H	LYS334
K	LYS334
O	LYS334
R	LYS334
V	LYS334

site_id	SWS_FT_FI12
Number of Residues	8
Details	MOD_RES: N-acetylproline => ECO:0000269\|PubMed:2928307

Chain	Residue	Details
L	PRO3
B	PRO3
E	PRO3
H	PRO3
K	PRO3
O	PRO3
R	PRO3
V	PRO3

site_id	SWS_FT_FI13
Number of Residues	8
Details	MOD_RES: N6-carboxylysine => ECO:0000269\|PubMed:14596800, ECO:0000269\|PubMed:2118958, ECO:0000269\|PubMed:8648644, ECO:0000269\|PubMed:9034362, ECO:0000269\|PubMed:9092835

Chain	Residue	Details
L	LYS201
B	LYS201
E	LYS201
H	LYS201
K	LYS201
O	LYS201
R	LYS201
V	LYS201

Catalytic Information from CSA

site_id	CSA1
Number of Residues	6
Details	Annotated By Reference To The Literature 1rbl

Chain	Residue	Details
L	LYS175
L	LYS201
L	LYS177
L	HIS294
L	ASP203
L	HIS327

site_id	CSA2
Number of Residues	6
Details	Annotated By Reference To The Literature 1rbl

Chain	Residue	Details
B	LYS175
B	LYS201
B	LYS177
B	HIS294
B	ASP203
B	HIS327

site_id	CSA3
Number of Residues	6
Details	Annotated By Reference To The Literature 1rbl

Chain	Residue	Details
E	LYS175
E	LYS201
E	LYS177
E	HIS294
E	ASP203
E	HIS327

site_id	CSA4
Number of Residues	6
Details	Annotated By Reference To The Literature 1rbl

Chain	Residue	Details
H	LYS175
H	LYS201
H	LYS177
H	HIS294
H	ASP203
H	HIS327

site_id	CSA5
Number of Residues	6
Details	Annotated By Reference To The Literature 1rbl

Chain	Residue	Details
K	LYS175
K	LYS201
K	LYS177
K	HIS294
K	ASP203
K	HIS327

site_id	CSA6
Number of Residues	6
Details	Annotated By Reference To The Literature 1rbl

Chain	Residue	Details
O	LYS175
O	LYS201
O	LYS177
O	HIS294
O	ASP203
O	HIS327

site_id	CSA7
Number of Residues	6
Details	Annotated By Reference To The Literature 1rbl

Chain	Residue	Details
R	LYS175
R	LYS201
R	LYS177
R	HIS294
R	ASP203
R	HIS327

site_id	CSA8
Number of Residues	6
Details	Annotated By Reference To The Literature 1rbl

Chain	Residue	Details
V	LYS175
V	LYS201
V	LYS177
V	HIS294
V	ASP203
V	HIS327

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)