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1RC5

CRYSTAL STRUCTURE OF MG(II)-COMPLEX OF RNASE III ENDONUCLEASE DOMAIN FROM AQUIFEX AEOLICUS AT 2.30 ANGSTROM RESOLUTION

Functional Information from GO Data
ChainGOidnamespacecontents
A0004525molecular_functionribonuclease III activity
A0006396biological_processRNA processing
B0004525molecular_functionribonuclease III activity
B0006396biological_processRNA processing
C0004525molecular_functionribonuclease III activity
C0006396biological_processRNA processing
D0004525molecular_functionribonuclease III activity
D0006396biological_processRNA processing
Functional Information from PDB Data
site_idAC1
Number of Residues6
DetailsBINDING SITE FOR RESIDUE MG A 761
ChainResidue
AGLU40
AASP107
AGLU110
AHOH1004
AHOH1056
AHOH1136

site_idAC2
Number of Residues6
DetailsBINDING SITE FOR RESIDUE MG B 762
ChainResidue
BHOH1007
BHOH1245
BHOH1319
BGLU240
BASP307
BGLU310

site_idAC3
Number of Residues6
DetailsBINDING SITE FOR RESIDUE MG C 763
ChainResidue
CGLU440
CASP507
CGLU510
CHOH1008
CHOH1015
CHOH1039

site_idAC4
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MG D 764
ChainResidue
DGLU640
DASP707
DGLU710
DHOH1123
DHOH1302

Functional Information from PROSITE/UniProt
site_idPS00517
Number of Residues9
DetailsRNASE_3_1 Ribonuclease III family signature. ETLEFLGDA
ChainResidueDetails
AGLU37-ALA45

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsACT_SITE: ACT_SITE => ECO:0000255
ChainResidueDetails
AASP44
BASP244
CASP444
DASP644

site_idSWS_FT_FI2
Number of Residues4
DetailsACT_SITE: ACT_SITE => ECO:0000305
ChainResidueDetails
AGLU110
BGLU310
CGLU510
DGLU710

site_idSWS_FT_FI3
Number of Residues12
DetailsBINDING: BINDING => ECO:0000269|PubMed:15016361, ECO:0000269|PubMed:18047582, ECO:0000305|PubMed:11738048, ECO:0007744|PDB:1JFZ, ECO:0007744|PDB:1RC5
ChainResidueDetails
AGLU40
DGLU640
DASP707
DGLU710
AASP107
AGLU110
BGLU240
BASP307
BGLU310
CGLU440
CASP507
CGLU510

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PDB entries from 2024-11-13

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