1R8C

Crystal Structures of an Archaeal Class I CCA-Adding Enzyme and Its Nucleotide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000049	molecular_function	tRNA binding
A	0000166	molecular_function	nucleotide binding
A	0000287	molecular_function	magnesium ion binding
A	0001680	biological_process	tRNA 3'-terminal CCA addition
A	0003723	molecular_function	RNA binding
A	0004810	molecular_function	CCA tRNA nucleotidyltransferase activity
A	0005524	molecular_function	ATP binding
A	0008033	biological_process	tRNA processing
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0031123	biological_process	RNA 3'-end processing
A	0042245	biological_process	RNA repair
A	0046872	molecular_function	metal ion binding
A	0106354	biological_process	tRNA surveillance
A	0160016	molecular_function	CCACCA tRNA nucleotidyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN A 600

Chain	Residue
A	GLU59
A	ASP61
A	UTP501
A	MN604

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN A 601

Chain	Residue
A	TYR90
A	HIS396
A	HIS398
A	UTP502

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN A 602

Chain	Residue
A	HIS101
A	ASP110
A	HOH908
A	ARG93

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN A 603

Chain	Residue
A	ARG129
A	HIS133
A	ASP218
A	HOH896

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN A 604

Chain	Residue
A	GLU59
A	ASP61
A	ASP110
A	UTP501
A	MN600
A	HOH750

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NA A 605

Chain	Residue
A	LYS205
A	SER391
A	THR395
A	HOH766

---

site_id	AC7
Number of Residues	18
Details	BINDING SITE FOR RESIDUE UTP A 501

Chain	Residue
A	GLY46
A	SER47
A	GLU59
A	ASP61
A	GLU96
A	ALA126
A	THR130
A	HIS133
A	LYS152
A	TYR161
A	MN600
A	MN604
A	HOH633
A	HOH673
A	HOH702
A	HOH774
A	HOH778
A	HOH806

---

site_id	AC8
Number of Residues	12
Details	BINDING SITE FOR RESIDUE UTP A 502

Chain	Residue
A	LYS84
A	TYR90
A	LYS303
A	ARG310
A	TYR392
A	HIS396
A	HIS398
A	THR399
A	MN601
A	HOH636
A	HOH707
A	HOH871

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"14592988","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14636575","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25640237","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1R89","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4X4O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4X4Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4X4S","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"14592988","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14636575","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25640237","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1R89","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4X4Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4X4S","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"14592988","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1UEV","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"14592988","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1R89","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UEV","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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