1R6X

The Crystal Structure of a Truncated Form of Yeast ATP Sulfurylase, Lacking the C-Terminal APS Kinase-like Domain, in complex with Sulfate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000103	biological_process	sulfate assimilation
A	0004781	molecular_function	sulfate adenylyltransferase (ATP) activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 2002

Chain	Residue
A	GLN195
A	ARG197
A	ALA293
A	HOH4071
A	HOH4111
A	HOH4205
A	HOH4393

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site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 2004

Chain	Residue
A	ASP168
A	ARG173
A	HOH4184
A	HOH4265
A	HOH4407
A	HIS166
A	TYR167

---

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 2005

Chain	Residue
A	ARG205
A	ARG213
A	HOH4364

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site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CO A 3000

Chain	Residue
A	ASP168
A	HIS235
A	HIS236
A	HOH4265
A	HOH4355

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	ACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_03106, ECO:0000305|PubMed:11157739

Chain	Residue	Details
A	THR196
A	ARG197
A	ASN198

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site_id	SWS_FT_FI2
Number of Residues	5
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_03106, ECO:0000269|PubMed:11157739

Chain	Residue	Details
A	GLN195
A	ARG197
A	GLY289
A	ALA293
A	VAL331

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	SITE: Transition state stabilizer => ECO:0000255|HAMAP-Rule:MF_03106, ECO:0000305|PubMed:11157739

Chain	Residue	Details
A	HIS201
A	HIS204

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	SITE: Induces change in substrate recognition on ATP binding => ECO:0000255|HAMAP-Rule:MF_03106, ECO:0000305|PubMed:11157739

Chain	Residue	Details
A	PHE328

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1j70

Chain	Residue	Details
A	HIS204
A	HIS201
A	ARG197

---

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1j70

Chain	Residue	Details
A	ARG290

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site_id	MCSA1
Number of Residues	5
Details	M-CSA 287

Chain	Residue	Details
A	THR196	electrostatic stabiliser, hydrogen bond donor, steric role
A	ARG197	electrostatic stabiliser, hydrogen bond donor, steric role
A	HIS201	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
A	HIS204	electrostatic stabiliser
A	ARG290	electrostatic stabiliser

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