1R52

Crystal structure of the bifunctional chorismate synthase from Saccharomyces cerevisiae

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004107	molecular_function	chorismate synthase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0008652	biological_process	amino acid biosynthetic process
A	0008752	molecular_function	FMN reductase (NAD(P)H) activity
A	0009073	biological_process	aromatic amino acid family biosynthetic process
A	0009423	biological_process	chorismate biosynthetic process
A	0010181	molecular_function	FMN binding
A	0016491	molecular_function	oxidoreductase activity
A	0016829	molecular_function	lyase activity
A	0042602	molecular_function	riboflavin reductase (NADPH) activity
A	0052873	molecular_function	FMN reductase (NADPH) activity
B	0004107	molecular_function	chorismate synthase activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0008652	biological_process	amino acid biosynthetic process
B	0008752	molecular_function	FMN reductase (NAD(P)H) activity
B	0009073	biological_process	aromatic amino acid family biosynthetic process
B	0009423	biological_process	chorismate biosynthetic process
B	0010181	molecular_function	FMN binding
B	0016491	molecular_function	oxidoreductase activity
B	0016829	molecular_function	lyase activity
B	0042602	molecular_function	riboflavin reductase (NADPH) activity
B	0052873	molecular_function	FMN reductase (NADPH) activity
C	0004107	molecular_function	chorismate synthase activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0008652	biological_process	amino acid biosynthetic process
C	0008752	molecular_function	FMN reductase (NAD(P)H) activity
C	0009073	biological_process	aromatic amino acid family biosynthetic process
C	0009423	biological_process	chorismate biosynthetic process
C	0010181	molecular_function	FMN binding
C	0016491	molecular_function	oxidoreductase activity
C	0016829	molecular_function	lyase activity
C	0042602	molecular_function	riboflavin reductase (NADPH) activity
C	0052873	molecular_function	FMN reductase (NADPH) activity
D	0004107	molecular_function	chorismate synthase activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0008652	biological_process	amino acid biosynthetic process
D	0008752	molecular_function	FMN reductase (NAD(P)H) activity
D	0009073	biological_process	aromatic amino acid family biosynthetic process
D	0009423	biological_process	chorismate biosynthetic process
D	0010181	molecular_function	FMN binding
D	0016491	molecular_function	oxidoreductase activity
D	0016829	molecular_function	lyase activity
D	0042602	molecular_function	riboflavin reductase (NADPH) activity
D	0052873	molecular_function	FMN reductase (NADPH) activity

Functional Information from PROSITE/UniProt

site_id	PS00787
Number of Residues	16
Details	CHORISMATE_SYNTHASE_1 Chorismate synthase signature 1. GESHCksVGcIVDGvP

Chain	Residue	Details
A	GLY14-PRO29

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site_id	PS00788
Number of Residues	17
Details	CHORISMATE_SYNTHASE_2 Chorismate synthase signature 2. GraSAReTigrVasGAI

Chain	Residue	Details
A	GLY122-ILE138

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site_id	PS00789
Number of Residues	17
Details	CHORISMATE_SYNTHASE_3 Chorismate synthase signature 3. RHDPAvtprAiPIvEAM

Chain	Residue	Details
A	ARG337-MET353

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	ACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:Q12640

Chain	Residue	Details
A	HIS17
D	HIS17
D	HIS104
D	ASP339
A	HIS104
A	ASP339
B	HIS17
B	HIS104
B	ASP339
C	HIS17
C	HIS104
C	ASP339

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site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: N-acetylserine => ECO:0007744|PubMed:22814378

Chain	Residue	Details
A	SER2
B	SER2
C	SER2
D	SER2

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