1R4A

Crystal Structure of GTP-bound ADP-ribosylation Factor Like Protein 1 (Arl1) and GRIP Domain of Golgin245 COMPLEX

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000139	cellular_component	Golgi membrane
A	0000166	molecular_function	nucleotide binding
A	0003924	molecular_function	GTPase activity
A	0005525	molecular_function	GTP binding
A	0005737	cellular_component	cytoplasm
A	0005794	cellular_component	Golgi apparatus
A	0005802	cellular_component	trans-Golgi network
A	0005829	cellular_component	cytosol
A	0006886	biological_process	intracellular protein transport
A	0007030	biological_process	Golgi organization
A	0008047	molecular_function	enzyme activator activity
A	0009404	biological_process	toxin metabolic process
A	0016020	cellular_component	membrane
A	0016192	biological_process	vesicle-mediated transport
A	0019904	molecular_function	protein domain specific binding
A	0034067	biological_process	protein localization to Golgi apparatus
A	0042147	biological_process	retrograde transport, endosome to Golgi
A	0046872	molecular_function	metal ion binding
A	0048193	biological_process	Golgi vesicle transport
A	1990583	molecular_function	phospholipase D activator activity
B	0000139	cellular_component	Golgi membrane
B	0000166	molecular_function	nucleotide binding
B	0003924	molecular_function	GTPase activity
B	0005525	molecular_function	GTP binding
B	0005737	cellular_component	cytoplasm
B	0005794	cellular_component	Golgi apparatus
B	0005802	cellular_component	trans-Golgi network
B	0005829	cellular_component	cytosol
B	0006886	biological_process	intracellular protein transport
B	0007030	biological_process	Golgi organization
B	0008047	molecular_function	enzyme activator activity
B	0009404	biological_process	toxin metabolic process
B	0016020	cellular_component	membrane
B	0016192	biological_process	vesicle-mediated transport
B	0019904	molecular_function	protein domain specific binding
B	0034067	biological_process	protein localization to Golgi apparatus
B	0042147	biological_process	retrograde transport, endosome to Golgi
B	0046872	molecular_function	metal ion binding
B	0048193	biological_process	Golgi vesicle transport
B	1990583	molecular_function	phospholipase D activator activity
C	0000139	cellular_component	Golgi membrane
C	0000166	molecular_function	nucleotide binding
C	0003924	molecular_function	GTPase activity
C	0005525	molecular_function	GTP binding
C	0005737	cellular_component	cytoplasm
C	0005794	cellular_component	Golgi apparatus
C	0005802	cellular_component	trans-Golgi network
C	0005829	cellular_component	cytosol
C	0006886	biological_process	intracellular protein transport
C	0007030	biological_process	Golgi organization
C	0008047	molecular_function	enzyme activator activity
C	0009404	biological_process	toxin metabolic process
C	0016020	cellular_component	membrane
C	0016192	biological_process	vesicle-mediated transport
C	0019904	molecular_function	protein domain specific binding
C	0034067	biological_process	protein localization to Golgi apparatus
C	0042147	biological_process	retrograde transport, endosome to Golgi
C	0046872	molecular_function	metal ion binding
C	0048193	biological_process	Golgi vesicle transport
C	1990583	molecular_function	phospholipase D activator activity
D	0000139	cellular_component	Golgi membrane
D	0000166	molecular_function	nucleotide binding
D	0003924	molecular_function	GTPase activity
D	0005525	molecular_function	GTP binding
D	0005737	cellular_component	cytoplasm
D	0005794	cellular_component	Golgi apparatus
D	0005802	cellular_component	trans-Golgi network
D	0005829	cellular_component	cytosol
D	0006886	biological_process	intracellular protein transport
D	0007030	biological_process	Golgi organization
D	0008047	molecular_function	enzyme activator activity
D	0009404	biological_process	toxin metabolic process
D	0016020	cellular_component	membrane
D	0016192	biological_process	vesicle-mediated transport
D	0019904	molecular_function	protein domain specific binding
D	0034067	biological_process	protein localization to Golgi apparatus
D	0042147	biological_process	retrograde transport, endosome to Golgi
D	0046872	molecular_function	metal ion binding
D	0048193	biological_process	Golgi vesicle transport
D	1990583	molecular_function	phospholipase D activator activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 901

Chain	Residue
A	THR31
A	THR45
A	ILE46
A	THR48
A	GNP1201

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG B 902

Chain	Residue
B	HOH1203
B	THR31
B	ILE46
B	THR48
B	GNP1202

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C 903

Chain	Residue
C	THR31
C	ILE46
C	THR48
C	GNP1203
C	HOH1260

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 904

Chain	Residue
D	THR31
D	ILE46
D	THR48
D	GNP1204

---

site_id	AC5
Number of Residues	20
Details	BINDING SITE FOR RESIDUE GNP A 1201

Chain	Residue
A	GLY27
A	ALA28
A	GLY29
A	LYS30
A	THR31
A	THR32
A	VAL43
A	THR45
A	THR48
A	GLY69
A	GLY70
A	ASN126
A	LYS127
A	ASP129
A	MET130
A	SER159
A	ALA160
A	THR161
A	MG901
A	HOH1203

---

site_id	AC6
Number of Residues	19
Details	BINDING SITE FOR RESIDUE GNP B 1202

Chain	Residue
B	GLY27
B	ALA28
B	GLY29
B	LYS30
B	THR31
B	THR32
B	VAL43
B	THR45
B	THR48
B	GLY69
B	GLY70
B	ASN126
B	LYS127
B	ASP129
B	SER159
B	ALA160
B	THR161
B	MG902
B	HOH1203

---

site_id	AC7
Number of Residues	22
Details	BINDING SITE FOR RESIDUE GNP C 1203

Chain	Residue
C	ASP26
C	GLY27
C	ALA28
C	GLY29
C	LYS30
C	THR31
C	THR32
C	VAL43
C	THR45
C	THR48
C	GLY69
C	GLY70
C	ASN126
C	LYS127
C	ASP129
C	SER159
C	ALA160
C	THR161
C	MG903
C	HOH1218
C	HOH1223
C	HOH1260

---

site_id	AC8
Number of Residues	21
Details	BINDING SITE FOR RESIDUE GNP D 1204

Chain	Residue
D	HOH1207
D	HOH1248
D	ASP26
D	GLY27
D	ALA28
D	GLY29
D	LYS30
D	THR31
D	THR32
D	VAL43
D	THR45
D	THR48
D	GLY70
D	ASN126
D	LYS127
D	ASP129
D	MET130
D	SER159
D	ALA160
D	THR161
D	MG904

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	28
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"14718928","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	32
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P40616","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
A	GLN71

---

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
B	GLN71

---

site_id	CSA3
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
C	GLN71

---

site_id	CSA4
Number of Residues	1
Details	Annotated By Reference To The Literature 1ksj

Chain	Residue	Details
D	GLN71

---