1R3E
Crystal Structure of tRNA Pseudouridine Synthase TruB and Its RNA Complex: RNA-protein Recognition Through a Combination of Rigid Docking and Induced Fit
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0001522 | biological_process | pseudouridine synthesis |
A | 0003723 | molecular_function | RNA binding |
A | 0006396 | biological_process | RNA processing |
A | 0006400 | biological_process | tRNA modification |
A | 0008033 | biological_process | tRNA processing |
A | 0009451 | biological_process | RNA modification |
A | 0009982 | molecular_function | pseudouridine synthase activity |
A | 0016853 | molecular_function | isomerase activity |
A | 0031119 | biological_process | tRNA pseudouridine synthesis |
A | 0034470 | biological_process | obsolete ncRNA processing |
A | 0106029 | molecular_function | tRNA pseudouridine synthase activity |
A | 0140098 | molecular_function | catalytic activity, acting on RNA |
A | 1990481 | biological_process | mRNA pseudouridine synthesis |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | ACT_SITE: Nucleophile => ECO:0000255|HAMAP-Rule:MF_01080 |
Chain | Residue | Details |
A | ASP48 |
Catalytic Information from CSA
site_id | MCSA1 |
Number of Residues | 4 |
Details | M-CSA 56 |
Chain | Residue | Details |
A | ASP48 | covalently attached, nucleofuge, nucleophile, proton acceptor, proton donor |
A | TYR76 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay, van der waals interaction |
A | ASP90 | activator, increase acidity, increase basicity, increase electrophilicity |
A | ARG181 | activator, increase acidity, increase basicity, increase electrophilicity |