Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004022 | molecular_function | alcohol dehydrogenase (NAD+) activity |
A | 0008270 | molecular_function | zinc ion binding |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0046872 | molecular_function | metal ion binding |
B | 0004022 | molecular_function | alcohol dehydrogenase (NAD+) activity |
B | 0008270 | molecular_function | zinc ion binding |
B | 0016491 | molecular_function | oxidoreductase activity |
B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE ZN A 500 |
Chain | Residue |
A | CYS38 |
A | HIS68 |
A | CYS154 |
A | NAD403 |
A | ETX600 |
site_id | AC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN A 400 |
Chain | Residue |
A | GLU98 |
A | CYS101 |
A | CYS104 |
A | CYS112 |
site_id | AC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE ZN B 500 |
Chain | Residue |
B | CYS38 |
B | HIS68 |
B | CYS154 |
B | NAD403 |
B | ETX600 |
site_id | AC4 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN B 400 |
Chain | Residue |
B | GLU98 |
B | CYS101 |
B | CYS104 |
B | CYS112 |
site_id | AC5 |
Number of Residues | 33 |
Details | BINDING SITE FOR RESIDUE NAD A 403 |
Chain | Residue |
A | CYS38 |
A | HIS39 |
A | SER40 |
A | HIS43 |
A | CYS154 |
A | THR158 |
A | GLY178 |
A | GLY180 |
A | GLY181 |
A | GLY182 |
A | LEU183 |
A | ASP203 |
A | VAL204 |
A | ARG205 |
A | LEU247 |
A | ASN248 |
A | VAL270 |
A | GLY271 |
A | LEU272 |
A | PHE273 |
A | SER294 |
A | LEU295 |
A | VAL296 |
A | LEU334 |
A | ARG342 |
A | ZN500 |
A | ETX600 |
A | HOH605 |
A | HOH613 |
A | HOH650 |
A | HOH664 |
A | HOH704 |
B | THR285 |
site_id | AC6 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE ETX A 600 |
Chain | Residue |
A | SER40 |
A | PHE49 |
A | HIS68 |
A | TRP95 |
A | TRP117 |
A | CYS154 |
A | NAD403 |
A | ZN500 |
site_id | AC7 |
Number of Residues | 33 |
Details | BINDING SITE FOR RESIDUE NAD B 403 |
Chain | Residue |
B | LEU334 |
B | ARG342 |
B | ZN500 |
B | ETX600 |
B | HOH606 |
B | HOH612 |
B | HOH617 |
B | HOH646 |
B | HOH654 |
A | THR285 |
B | CYS38 |
B | HIS39 |
B | SER40 |
B | HIS43 |
B | CYS154 |
B | THR158 |
B | GLY178 |
B | GLY180 |
B | GLY181 |
B | GLY182 |
B | LEU183 |
B | ASP203 |
B | VAL204 |
B | ARG205 |
B | LEU247 |
B | ASN248 |
B | VAL270 |
B | GLY271 |
B | LEU272 |
B | PHE273 |
B | SER294 |
B | LEU295 |
B | VAL296 |
site_id | AC8 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE ETX B 600 |
Chain | Residue |
B | SER40 |
B | PHE49 |
B | HIS68 |
B | TRP95 |
B | TRP117 |
B | CYS154 |
B | NAD403 |
B | ZN500 |
site_id | ZNC |
Number of Residues | 4 |
Details | RESIDUES THAT BIND THE CATALYTIC ZINC ION (ZN A 500) |
Chain | Residue |
A | CYS38 |
A | CYS154 |
A | HIS68 |
A | ETX600 |
site_id | ZND |
Number of Residues | 4 |
Details | RESIDUES THAT BIND THE CATALYTIC ZINC ION (ZN B 500) |
Chain | Residue |
B | CYS38 |
B | CYS154 |
B | HIS68 |
B | ETX600 |
site_id | ZNS |
Number of Residues | 4 |
Details | RESIDUES THAT BIND A STRUCTURAL ZINC ION (ZN A 400) IN THE CATALYTIC DOMAIN |
Chain | Residue |
A | CYS112 |
A | GLU98 |
A | CYS101 |
A | CYS104 |
site_id | ZNT |
Number of Residues | 4 |
Details | RESIDUES THAT BIND A STRUCTURAL ZINC ION (ZN B 400) IN THE CATALYTIC DOMAIN |
Chain | Residue |
B | GLU98 |
B | CYS101 |
B | CYS104 |
B | CYS112 |
Functional Information from PROSITE/UniProt
site_id | PS00059 |
Number of Residues | 15 |
Details | ADH_ZINC Zinc-containing alcohol dehydrogenases signature. GHEiAGKieevGdeV |
Chain | Residue | Details |
A | GLY67-VAL81 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 14 |
Details | BINDING: |
Chain | Residue | Details |
A | CYS38 | |
B | GLU98 | |
B | CYS101 | |
B | CYS104 | |
B | CYS112 | |
B | CYS154 | |
A | HIS68 | |
A | GLU98 | |
A | CYS101 | |
A | CYS104 | |
A | CYS112 | |
A | CYS154 | |
B | CYS38 | |
B | HIS68 | |
Chain | Residue | Details |
A | LYS11 | |
A | LYS213 | |
B | LYS11 | |
B | LYS213 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1teh |
Chain | Residue | Details |
A | SER40 | |
A | HIS39 | |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1teh |
Chain | Residue | Details |
B | SER40 | |
B | HIS39 | |
site_id | CSA3 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1teh |
Chain | Residue | Details |
A | PHE49 | |
site_id | CSA4 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1teh |
Chain | Residue | Details |
B | PHE49 | |
site_id | CSA5 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1teh |
Chain | Residue | Details |
A | SER40 | |
A | HIS43 | |
site_id | CSA6 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1teh |
Chain | Residue | Details |
B | SER40 | |
B | HIS43 | |