Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004022 | molecular_function | alcohol dehydrogenase (NAD+) activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004022 | molecular_function | alcohol dehydrogenase (NAD+) activity |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 500 |
| Chain | Residue |
| A | CYS38 |
| A | HIS68 |
| A | CYS154 |
| A | NAD403 |
| A | ETX600 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 400 |
| Chain | Residue |
| A | GLU98 |
| A | CYS101 |
| A | CYS104 |
| A | CYS112 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 500 |
| Chain | Residue |
| B | CYS38 |
| B | HIS68 |
| B | CYS154 |
| B | NAD403 |
| B | ETX600 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 400 |
| Chain | Residue |
| B | GLU98 |
| B | CYS101 |
| B | CYS104 |
| B | CYS112 |
| site_id | AC5 |
| Number of Residues | 33 |
| Details | BINDING SITE FOR RESIDUE NAD A 403 |
| Chain | Residue |
| A | CYS38 |
| A | HIS39 |
| A | SER40 |
| A | HIS43 |
| A | CYS154 |
| A | THR158 |
| A | GLY178 |
| A | GLY180 |
| A | GLY181 |
| A | GLY182 |
| A | LEU183 |
| A | ASP203 |
| A | VAL204 |
| A | ARG205 |
| A | LEU247 |
| A | ASN248 |
| A | VAL270 |
| A | GLY271 |
| A | LEU272 |
| A | PHE273 |
| A | SER294 |
| A | LEU295 |
| A | VAL296 |
| A | LEU334 |
| A | ARG342 |
| A | ZN500 |
| A | ETX600 |
| A | HOH605 |
| A | HOH613 |
| A | HOH650 |
| A | HOH664 |
| A | HOH704 |
| B | THR285 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ETX A 600 |
| Chain | Residue |
| A | SER40 |
| A | PHE49 |
| A | HIS68 |
| A | TRP95 |
| A | TRP117 |
| A | CYS154 |
| A | NAD403 |
| A | ZN500 |
| site_id | AC7 |
| Number of Residues | 33 |
| Details | BINDING SITE FOR RESIDUE NAD B 403 |
| Chain | Residue |
| B | LEU334 |
| B | ARG342 |
| B | ZN500 |
| B | ETX600 |
| B | HOH606 |
| B | HOH612 |
| B | HOH617 |
| B | HOH646 |
| B | HOH654 |
| A | THR285 |
| B | CYS38 |
| B | HIS39 |
| B | SER40 |
| B | HIS43 |
| B | CYS154 |
| B | THR158 |
| B | GLY178 |
| B | GLY180 |
| B | GLY181 |
| B | GLY182 |
| B | LEU183 |
| B | ASP203 |
| B | VAL204 |
| B | ARG205 |
| B | LEU247 |
| B | ASN248 |
| B | VAL270 |
| B | GLY271 |
| B | LEU272 |
| B | PHE273 |
| B | SER294 |
| B | LEU295 |
| B | VAL296 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ETX B 600 |
| Chain | Residue |
| B | SER40 |
| B | PHE49 |
| B | HIS68 |
| B | TRP95 |
| B | TRP117 |
| B | CYS154 |
| B | NAD403 |
| B | ZN500 |
| site_id | ZNC |
| Number of Residues | 4 |
| Details | RESIDUES THAT BIND THE CATALYTIC ZINC ION (ZN A 500) |
| Chain | Residue |
| A | CYS38 |
| A | CYS154 |
| A | HIS68 |
| A | ETX600 |
| site_id | ZND |
| Number of Residues | 4 |
| Details | RESIDUES THAT BIND THE CATALYTIC ZINC ION (ZN B 500) |
| Chain | Residue |
| B | CYS38 |
| B | CYS154 |
| B | HIS68 |
| B | ETX600 |
| site_id | ZNS |
| Number of Residues | 4 |
| Details | RESIDUES THAT BIND A STRUCTURAL ZINC ION (ZN A 400) IN THE CATALYTIC DOMAIN |
| Chain | Residue |
| A | CYS112 |
| A | GLU98 |
| A | CYS101 |
| A | CYS104 |
| site_id | ZNT |
| Number of Residues | 4 |
| Details | RESIDUES THAT BIND A STRUCTURAL ZINC ION (ZN B 400) IN THE CATALYTIC DOMAIN |
| Chain | Residue |
| B | GLU98 |
| B | CYS101 |
| B | CYS104 |
| B | CYS112 |
Functional Information from PROSITE/UniProt
| site_id | PS00059 |
| Number of Residues | 15 |
| Details | ADH_ZINC Zinc-containing alcohol dehydrogenases signature. GHEiAGKieevGdeV |
| Chain | Residue | Details |
| A | GLY67-VAL81 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 14 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | CYS38 | |
| B | GLU98 | |
| B | CYS101 | |
| B | CYS104 | |
| B | CYS112 | |
| B | CYS154 | |
| A | HIS68 | |
| A | GLU98 | |
| A | CYS101 | |
| A | CYS104 | |
| A | CYS112 | |
| A | CYS154 | |
| B | CYS38 | |
| B | HIS68 | |
| Chain | Residue | Details |
| A | LYS11 | |
| A | LYS213 | |
| B | LYS11 | |
| B | LYS213 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1teh |
| Chain | Residue | Details |
| A | SER40 | |
| A | HIS39 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1teh |
| Chain | Residue | Details |
| B | SER40 | |
| B | HIS39 | |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1teh |
| Chain | Residue | Details |
| A | PHE49 | |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1teh |
| Chain | Residue | Details |
| B | PHE49 | |
| site_id | CSA5 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1teh |
| Chain | Residue | Details |
| A | SER40 | |
| A | HIS43 | |
| site_id | CSA6 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1teh |
| Chain | Residue | Details |
| B | SER40 | |
| B | HIS43 | |
