Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006569 | biological_process | L-tryptophan catabolic process |
| A | 0009435 | biological_process | NAD+ biosynthetic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0019363 | biological_process | pyridine nucleotide biosynthetic process |
| A | 0019441 | biological_process | L-tryptophan catabolic process to kynurenine |
| A | 0019805 | biological_process | quinolinate biosynthetic process |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0030429 | molecular_function | kynureninase activity |
| A | 0043420 | biological_process | anthranilate metabolic process |
| A | 0097053 | biological_process | L-kynurenine catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 601 |
| Chain | Residue |
| A | HIS204 |
| A | ARG375 |
| A | HOH1353 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE PLP A 1227 |
| Chain | Residue |
| A | THR172 |
| A | ASP201 |
| A | ALA203 |
| A | HIS204 |
| A | CYS224 |
| A | TYR226 |
| A | LYS227 |
| A | TRP256 |
| A | GLY281 |
| A | THR282 |
| A | HOH1256 |
| A | THR96 |
| A | THR97 |
| A | SER98 |
| A | PHE129 |
| A | THR131 |
| A | ASP132 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE P3G A 701 |
| Chain | Residue |
| A | TRP256 |
| A | HIS259 |
| A | ARG261 |
| A | MET265 |
| A | ARG369 |
| A | HOH1636 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 5 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01970","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"14756555","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"14756555","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-(pyridoxal phosphate)lysine"} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | a catalytic site defined by CSA, PubMed 14756555 |
| Chain | Residue | Details |
| A | ASP201 | |
| A | PHE129 | |
| A | LYS227 | |
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 742 |
| Chain | Residue | Details |
| A | PHE129 | electrostatic stabiliser |
| A | ASP201 | electrostatic stabiliser |
| A | TYR226 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay |
| A | LYS227 | electron pair acceptor, nucleofuge, nucleophile, proton acceptor, proton donor |
| A | ARG375 | electrostatic stabiliser |
