1QXH

Crystal Structure of Escherichia coli Thiol Peroxidase in the Oxidized State

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004601	molecular_function	peroxidase activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0008379	molecular_function	thioredoxin peroxidase activity
A	0016209	molecular_function	antioxidant activity
A	0016491	molecular_function	oxidoreductase activity
A	0016684	molecular_function	oxidoreductase activity, acting on peroxide as acceptor
A	0032843	molecular_function	hydroperoxide reductase activity
A	0034599	biological_process	cellular response to oxidative stress
A	0042597	cellular_component	periplasmic space
A	0098869	biological_process	cellular oxidant detoxification
A	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity
B	0004601	molecular_function	peroxidase activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0008379	molecular_function	thioredoxin peroxidase activity
B	0016209	molecular_function	antioxidant activity
B	0016491	molecular_function	oxidoreductase activity
B	0016684	molecular_function	oxidoreductase activity, acting on peroxide as acceptor
B	0032843	molecular_function	hydroperoxide reductase activity
B	0034599	biological_process	cellular response to oxidative stress
B	0042597	cellular_component	periplasmic space
B	0098869	biological_process	cellular oxidant detoxification
B	0140824	molecular_function	thioredoxin-dependent peroxiredoxin activity

Functional Information from PROSITE/UniProt

site_id	PS01265
Number of Residues	12
Details	TPX Tpx family signature. SaDLPFAqsRFC

Chain	Residue	Details
A	SER84-CYS95

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Cysteine sulfenic acid (-SOH) intermediate","evidences":[{"source":"HAMAP-Rule","id":"MF_00269","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"12514184","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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