1QWN
GOLGI ALPHA-MANNOSIDASE II Covalent Intermediate Complex with 5-fluoro-gulosyl-fluoride
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000139 | cellular_component | Golgi membrane |
| A | 0004559 | molecular_function | alpha-mannosidase activity |
| A | 0004572 | molecular_function | mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0005794 | cellular_component | Golgi apparatus |
| A | 0005795 | cellular_component | Golgi stack |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0006013 | biological_process | mannose metabolic process |
| A | 0006491 | biological_process | N-glycan processing |
| A | 0015923 | molecular_function | mannosidase activity |
| A | 0016063 | biological_process | rhodopsin biosynthetic process |
| A | 0030246 | molecular_function | carbohydrate binding |
| A | 0035010 | biological_process | encapsulation of foreign target |
| A | 1904381 | biological_process | Golgi apparatus N-glycan mannose trimming |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details |
| Chain | Residue | Details |
| A | ASP204 | |
| A | ASP341 |
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 793 |
| Chain | Residue | Details |
| A | HIS90 | metal ligand |
| A | ASP92 | metal ligand |
| A | ASP204 | covalently attached, metal ligand, nucleofuge, nucleophile |
| A | ASP341 | activator, increase nucleophilicity, proton acceptor, proton donor |
| A | HIS471 | metal ligand |
