Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004096 | molecular_function | catalase activity |
| A | 0004601 | molecular_function | peroxidase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006979 | biological_process | response to oxidative stress |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0020037 | molecular_function | heme binding |
| A | 0042542 | biological_process | response to hydrogen peroxide |
| A | 0042744 | biological_process | hydrogen peroxide catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0098869 | biological_process | cellular oxidant detoxification |
| B | 0004096 | molecular_function | catalase activity |
| B | 0004601 | molecular_function | peroxidase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006979 | biological_process | response to oxidative stress |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0020037 | molecular_function | heme binding |
| B | 0042542 | biological_process | response to hydrogen peroxide |
| B | 0042744 | biological_process | hydrogen peroxide catabolic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE AZI A 2600 |
| Chain | Residue |
| A | ARG47 |
| A | ARG344 |
| A | FMT1713 |
| A | FMT1735 |
| B | ARG47 |
| B | TYR345 |
| site_id | AC2 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE HEM A 550 |
| Chain | Residue |
| A | VAL55 |
| A | HIS56 |
| A | ARG93 |
| A | GLY112 |
| A | VAL127 |
| A | GLY128 |
| A | ASN129 |
| A | ALA139 |
| A | PHE142 |
| A | GLY197 |
| A | SER198 |
| A | HIS199 |
| A | PHE315 |
| A | MET331 |
| A | ARG335 |
| A | SER338 |
| A | TYR339 |
| A | THR342 |
| A | HIS343 |
| A | ARG346 |
| A | FMT1701 |
| A | HOH2606 |
| A | HOH2629 |
| A | HOH2668 |
| A | ASP46 |
| A | ARG53 |
| A | VAL54 |
| site_id | AC3 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE HEM B 550 |
| Chain | Residue |
| B | ASP46 |
| B | ARG53 |
| B | VAL54 |
| B | VAL55 |
| B | HIS56 |
| B | ARG93 |
| B | GLY112 |
| B | PHE113 |
| B | ALA114 |
| B | VAL127 |
| B | GLY128 |
| B | ASN129 |
| B | ALA139 |
| B | PHE142 |
| B | GLY197 |
| B | SER198 |
| B | PHE315 |
| B | MET331 |
| B | ARG335 |
| B | SER338 |
| B | TYR339 |
| B | THR342 |
| B | HIS343 |
| B | ARG346 |
| B | FMT1702 |
| B | HOH1739 |
| B | HOH1745 |
| B | HOH1792 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FMT A 1701 |
| Chain | Residue |
| A | HIS56 |
| A | ASN129 |
| A | PHE134 |
| A | PHE142 |
| A | HEM550 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FMT B 1702 |
| Chain | Residue |
| B | HIS56 |
| B | VAL97 |
| B | ASN129 |
| B | PHE134 |
| B | HEM550 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FMT B 1703 |
| Chain | Residue |
| B | ARG108 |
| B | ASP109 |
| B | PRO110 |
| B | PHE135 |
| B | GLN149 |
| B | VAL180 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FMT A 1704 |
| Chain | Residue |
| A | GLN149 |
| A | VAL163 |
| A | TRP167 |
| A | MET181 |
| A | HOH3041 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FMT B 1705 |
| Chain | Residue |
| B | GLN149 |
| B | PRO158 |
| B | VAL163 |
| B | FMT1707 |
| B | HOH1827 |
| B | HOH2015 |
| B | HOH2224 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT A 1706 |
| Chain | Residue |
| A | PRO158 |
| A | HIS160 |
| A | HOH2784 |
| A | HOH2855 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT B 1707 |
| Chain | Residue |
| B | FMT1705 |
| B | HOH1977 |
| B | HOH2112 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FMT B 1708 |
| Chain | Residue |
| B | HIS454 |
| B | HOH1817 |
| B | HOH1986 |
| B | HIS160 |
| B | GLU450 |
| B | SER451 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FMT A 1709 |
| Chain | Residue |
| A | ASP183 |
| A | ARG184 |
| A | VAL223 |
| A | GLU440 |
| A | HOH2717 |
| A | HOH2732 |
| site_id | BC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE FMT A 1710 |
| Chain | Residue |
| A | LYS58 |
| A | ARG101 |
| A | GLY102 |
| A | ARG151 |
| A | ASN156 |
| A | FMT1734 |
| A | HOH2845 |
| A | HOH2890 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FMT A 1711 |
| Chain | Residue |
| A | LYS150 |
| A | ARG151 |
| A | HOH2607 |
| A | HOH2652 |
| A | HOH3040 |
| site_id | BC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE FMT B 1712 |
| Chain | Residue |
| B | ALA57 |
| B | LYS58 |
| B | GLY59 |
| B | ARG101 |
| B | TYR306 |
| B | GLU311 |
| B | FMT1720 |
| B | HOH2207 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FMT A 1713 |
| Chain | Residue |
| A | ARG47 |
| A | TYR345 |
| A | AZI2600 |
| A | HOH2654 |
| B | ARG344 |
| site_id | BC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FMT A 1714 |
| Chain | Residue |
| A | ASN130 |
| A | TRP179 |
| A | ARG184 |
| A | ASP194 |
| A | HOH2694 |
| site_id | BC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE FMT A 1715 |
| Chain | Residue |
| A | TYR371 |
| B | TYR371 |
| site_id | CC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FMT A 1716 |
| Chain | Residue |
| A | PRO352 |
| A | GLN353 |
| A | PRO359 |
| A | PHE363 |
| A | HOH2791 |
| A | HOH2860 |
| B | ALA11 |
| site_id | CC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT B 1717 |
| Chain | Residue |
| B | TYR285 |
| B | THR286 |
| B | HOH2133 |
| site_id | CC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT A 1718 |
| Chain | Residue |
| A | PHE247 |
| A | ALA251 |
| A | ASN302 |
| A | HOH2725 |
| site_id | CC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FMT A 1719 |
| Chain | Residue |
| A | LYS77 |
| A | GLY323 |
| A | SER396 |
| A | ALA397 |
| A | ARG398 |
| site_id | CC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE FMT B 1720 |
| Chain | Residue |
| B | LYS58 |
| B | ARG101 |
| B | GLY102 |
| B | ARG151 |
| B | ASN156 |
| B | FMT1712 |
| B | HOH2050 |
| B | HOH2207 |
| site_id | CC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE FMT B 1721 |
| Chain | Residue |
| A | HOH2634 |
| B | ARG49 |
| B | ARG101 |
| B | HOH1801 |
| B | HOH1916 |
| B | HOH2050 |
| B | HOH2085 |
| B | HOH2177 |
| site_id | CC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT A 1722 |
| Chain | Residue |
| A | ASP194 |
| A | HIS218 |
| A | THR219 |
| A | HOH2928 |
| site_id | CC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT A 1723 |
| Chain | Residue |
| A | VAL223 |
| A | LYS224 |
| A | HOH2688 |
| A | HOH2978 |
| site_id | CC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT A 1724 |
| Chain | Residue |
| A | LYS188 |
| A | HOH2688 |
| A | HOH2925 |
| site_id | DC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT A 1725 |
| Chain | Residue |
| A | LYS188 |
| A | LEU226 |
| A | HOH2925 |
| A | HOH2956 |
| site_id | DC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT B 1726 |
| Chain | Residue |
| B | VAL223 |
| B | LYS224 |
| B | HOH1830 |
| site_id | DC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT B 1727 |
| Chain | Residue |
| B | ASP183 |
| B | HIS225 |
| B | GLU440 |
| site_id | DC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT B 1728 |
| Chain | Residue |
| B | LYS188 |
| B | LYS224 |
| B | HOH1830 |
| B | HOH2143 |
| site_id | DC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE FMT B 1729 |
| Chain | Residue |
| B | SER182 |
| B | ASP183 |
| B | ARG184 |
| B | TYR432 |
| B | LEU436 |
| B | GLU440 |
| B | HOH1897 |
| B | HOH2000 |
| B | HOH2225 |
| site_id | DC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FMT A 1730 |
| Chain | Residue |
| A | TYR371 |
| A | TYR371 |
| A | FMT1735 |
| B | PRO51 |
| B | TYR345 |
| site_id | DC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FMT B 1731 |
| Chain | Residue |
| B | LEU336 |
| B | PHE337 |
| B | ASP341 |
| B | ARG344 |
| B | FMT1736 |
| site_id | DC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT A 1732 |
| Chain | Residue |
| A | LEU336 |
| A | PHE337 |
| A | ARG344 |
| A | FMT1733 |
| site_id | DC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE FMT A 1733 |
| Chain | Residue |
| A | ALA318 |
| A | ARG344 |
| A | FMT1732 |
| A | HOH2787 |
| B | THR36 |
| B | LEU39 |
| B | GLU40 |
| B | HOH1800 |
| B | HOH2160 |
| site_id | EC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE FMT A 1734 |
| Chain | Residue |
| A | ALA57 |
| A | LYS58 |
| A | GLY59 |
| A | ARG101 |
| A | TYR306 |
| A | GLU311 |
| A | FMT1710 |
| A | HOH2845 |
| site_id | EC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FMT A 1735 |
| Chain | Residue |
| A | ARG344 |
| A | FMT1730 |
| A | AZI2600 |
| A | HOH2727 |
| A | HOH2867 |
| B | ARG47 |
| B | TYR345 |
| site_id | EC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE FMT B 1736 |
| Chain | Residue |
| A | THR36 |
| A | LEU39 |
| A | GLU40 |
| B | ALA318 |
| B | ARG344 |
| B | FMT1731 |
| B | HOH1917 |
| B | HOH2011 |
| B | HOH2179 |
Functional Information from PROSITE/UniProt
| site_id | PS00437 |
| Number of Residues | 9 |
| Details | CATALASE_1 Catalase proximal heme-ligand signature. RLFSYgDTH |
| Chain | Residue | Details |
| A | ARG335-HIS343 | |
| site_id | PS00438 |
| Number of Residues | 17 |
| Details | CATALASE_2 Catalase proximal active site signature. FdReripERvvHakGSG |
| Chain | Residue | Details |
| A | PHE45-GLY61 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10013","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"axial binding residue","evidences":[{"evidenceCode":"ECO:0000250"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1iph |
| Chain | Residue | Details |
| A | HIS56 | |
| A | SER95 | |
| A | ASN129 | |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1iph |
| Chain | Residue | Details |
| B | HIS56 | |
| B | SER95 | |
| B | ASN129 | |
