Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004096 | molecular_function | catalase activity |
A | 0004601 | molecular_function | peroxidase activity |
A | 0005515 | molecular_function | protein binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0006979 | biological_process | response to oxidative stress |
A | 0020037 | molecular_function | heme binding |
A | 0042542 | biological_process | response to hydrogen peroxide |
A | 0042744 | biological_process | hydrogen peroxide catabolic process |
A | 0046872 | molecular_function | metal ion binding |
A | 0098869 | biological_process | cellular oxidant detoxification |
B | 0004096 | molecular_function | catalase activity |
B | 0004601 | molecular_function | peroxidase activity |
B | 0005515 | molecular_function | protein binding |
B | 0005737 | cellular_component | cytoplasm |
B | 0006979 | biological_process | response to oxidative stress |
B | 0020037 | molecular_function | heme binding |
B | 0042542 | biological_process | response to hydrogen peroxide |
B | 0042744 | biological_process | hydrogen peroxide catabolic process |
B | 0046872 | molecular_function | metal ion binding |
B | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE AZI A 2600 |
Chain | Residue |
A | ARG47 |
A | ARG344 |
A | FMT1713 |
A | FMT1735 |
B | ARG47 |
B | TYR345 |
site_id | AC2 |
Number of Residues | 27 |
Details | BINDING SITE FOR RESIDUE HEM A 550 |
Chain | Residue |
A | VAL55 |
A | HIS56 |
A | ARG93 |
A | GLY112 |
A | VAL127 |
A | GLY128 |
A | ASN129 |
A | ALA139 |
A | PHE142 |
A | GLY197 |
A | SER198 |
A | HIS199 |
A | PHE315 |
A | MET331 |
A | ARG335 |
A | SER338 |
A | TYR339 |
A | THR342 |
A | HIS343 |
A | ARG346 |
A | FMT1701 |
A | HOH2606 |
A | HOH2629 |
A | HOH2668 |
A | ASP46 |
A | ARG53 |
A | VAL54 |
site_id | AC3 |
Number of Residues | 28 |
Details | BINDING SITE FOR RESIDUE HEM B 550 |
Chain | Residue |
B | ASP46 |
B | ARG53 |
B | VAL54 |
B | VAL55 |
B | HIS56 |
B | ARG93 |
B | GLY112 |
B | PHE113 |
B | ALA114 |
B | VAL127 |
B | GLY128 |
B | ASN129 |
B | ALA139 |
B | PHE142 |
B | GLY197 |
B | SER198 |
B | PHE315 |
B | MET331 |
B | ARG335 |
B | SER338 |
B | TYR339 |
B | THR342 |
B | HIS343 |
B | ARG346 |
B | FMT1702 |
B | HOH1739 |
B | HOH1745 |
B | HOH1792 |
site_id | AC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE FMT A 1701 |
Chain | Residue |
A | HIS56 |
A | ASN129 |
A | PHE134 |
A | PHE142 |
A | HEM550 |
site_id | AC5 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE FMT B 1702 |
Chain | Residue |
B | HIS56 |
B | VAL97 |
B | ASN129 |
B | PHE134 |
B | HEM550 |
site_id | AC6 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE FMT B 1703 |
Chain | Residue |
B | ARG108 |
B | ASP109 |
B | PRO110 |
B | PHE135 |
B | GLN149 |
B | VAL180 |
site_id | AC7 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE FMT A 1704 |
Chain | Residue |
A | GLN149 |
A | VAL163 |
A | TRP167 |
A | MET181 |
A | HOH3041 |
site_id | AC8 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE FMT B 1705 |
Chain | Residue |
B | GLN149 |
B | PRO158 |
B | VAL163 |
B | FMT1707 |
B | HOH1827 |
B | HOH2015 |
B | HOH2224 |
site_id | AC9 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE FMT A 1706 |
Chain | Residue |
A | PRO158 |
A | HIS160 |
A | HOH2784 |
A | HOH2855 |
site_id | BC1 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE FMT B 1707 |
Chain | Residue |
B | FMT1705 |
B | HOH1977 |
B | HOH2112 |
site_id | BC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE FMT B 1708 |
Chain | Residue |
B | HIS454 |
B | HOH1817 |
B | HOH1986 |
B | HIS160 |
B | GLU450 |
B | SER451 |
site_id | BC3 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE FMT A 1709 |
Chain | Residue |
A | ASP183 |
A | ARG184 |
A | VAL223 |
A | GLU440 |
A | HOH2717 |
A | HOH2732 |
site_id | BC4 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE FMT A 1710 |
Chain | Residue |
A | LYS58 |
A | ARG101 |
A | GLY102 |
A | ARG151 |
A | ASN156 |
A | FMT1734 |
A | HOH2845 |
A | HOH2890 |
site_id | BC5 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE FMT A 1711 |
Chain | Residue |
A | LYS150 |
A | ARG151 |
A | HOH2607 |
A | HOH2652 |
A | HOH3040 |
site_id | BC6 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE FMT B 1712 |
Chain | Residue |
B | ALA57 |
B | LYS58 |
B | GLY59 |
B | ARG101 |
B | TYR306 |
B | GLU311 |
B | FMT1720 |
B | HOH2207 |
site_id | BC7 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE FMT A 1713 |
Chain | Residue |
A | ARG47 |
A | TYR345 |
A | AZI2600 |
A | HOH2654 |
B | ARG344 |
site_id | BC8 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE FMT A 1714 |
Chain | Residue |
A | ASN130 |
A | TRP179 |
A | ARG184 |
A | ASP194 |
A | HOH2694 |
site_id | BC9 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE FMT A 1715 |
Chain | Residue |
A | TYR371 |
B | TYR371 |
site_id | CC1 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE FMT A 1716 |
Chain | Residue |
A | PRO352 |
A | GLN353 |
A | PRO359 |
A | PHE363 |
A | HOH2791 |
A | HOH2860 |
B | ALA11 |
site_id | CC2 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE FMT B 1717 |
Chain | Residue |
B | TYR285 |
B | THR286 |
B | HOH2133 |
site_id | CC3 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE FMT A 1718 |
Chain | Residue |
A | PHE247 |
A | ALA251 |
A | ASN302 |
A | HOH2725 |
site_id | CC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE FMT A 1719 |
Chain | Residue |
A | LYS77 |
A | GLY323 |
A | SER396 |
A | ALA397 |
A | ARG398 |
site_id | CC5 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE FMT B 1720 |
Chain | Residue |
B | LYS58 |
B | ARG101 |
B | GLY102 |
B | ARG151 |
B | ASN156 |
B | FMT1712 |
B | HOH2050 |
B | HOH2207 |
site_id | CC6 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE FMT B 1721 |
Chain | Residue |
A | HOH2634 |
B | ARG49 |
B | ARG101 |
B | HOH1801 |
B | HOH1916 |
B | HOH2050 |
B | HOH2085 |
B | HOH2177 |
site_id | CC7 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE FMT A 1722 |
Chain | Residue |
A | ASP194 |
A | HIS218 |
A | THR219 |
A | HOH2928 |
site_id | CC8 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE FMT A 1723 |
Chain | Residue |
A | VAL223 |
A | LYS224 |
A | HOH2688 |
A | HOH2978 |
site_id | CC9 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE FMT A 1724 |
Chain | Residue |
A | LYS188 |
A | HOH2688 |
A | HOH2925 |
site_id | DC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE FMT A 1725 |
Chain | Residue |
A | LYS188 |
A | LEU226 |
A | HOH2925 |
A | HOH2956 |
site_id | DC2 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE FMT B 1726 |
Chain | Residue |
B | VAL223 |
B | LYS224 |
B | HOH1830 |
site_id | DC3 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE FMT B 1727 |
Chain | Residue |
B | ASP183 |
B | HIS225 |
B | GLU440 |
site_id | DC4 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE FMT B 1728 |
Chain | Residue |
B | LYS188 |
B | LYS224 |
B | HOH1830 |
B | HOH2143 |
site_id | DC5 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE FMT B 1729 |
Chain | Residue |
B | SER182 |
B | ASP183 |
B | ARG184 |
B | TYR432 |
B | LEU436 |
B | GLU440 |
B | HOH1897 |
B | HOH2000 |
B | HOH2225 |
site_id | DC6 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE FMT A 1730 |
Chain | Residue |
A | TYR371 |
A | TYR371 |
A | FMT1735 |
B | PRO51 |
B | TYR345 |
site_id | DC7 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE FMT B 1731 |
Chain | Residue |
B | LEU336 |
B | PHE337 |
B | ASP341 |
B | ARG344 |
B | FMT1736 |
site_id | DC8 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE FMT A 1732 |
Chain | Residue |
A | LEU336 |
A | PHE337 |
A | ARG344 |
A | FMT1733 |
site_id | DC9 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE FMT A 1733 |
Chain | Residue |
A | ALA318 |
A | ARG344 |
A | FMT1732 |
A | HOH2787 |
B | THR36 |
B | LEU39 |
B | GLU40 |
B | HOH1800 |
B | HOH2160 |
site_id | EC1 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE FMT A 1734 |
Chain | Residue |
A | ALA57 |
A | LYS58 |
A | GLY59 |
A | ARG101 |
A | TYR306 |
A | GLU311 |
A | FMT1710 |
A | HOH2845 |
site_id | EC2 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE FMT A 1735 |
Chain | Residue |
A | ARG344 |
A | FMT1730 |
A | AZI2600 |
A | HOH2727 |
A | HOH2867 |
B | ARG47 |
B | TYR345 |
site_id | EC3 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE FMT B 1736 |
Chain | Residue |
A | THR36 |
A | LEU39 |
A | GLU40 |
B | ALA318 |
B | ARG344 |
B | FMT1731 |
B | HOH1917 |
B | HOH2011 |
B | HOH2179 |
Functional Information from PROSITE/UniProt
site_id | PS00437 |
Number of Residues | 9 |
Details | CATALASE_1 Catalase proximal heme-ligand signature. RLFSYgDTH |
Chain | Residue | Details |
A | ARG335-HIS343 | |
site_id | PS00438 |
Number of Residues | 17 |
Details | CATALASE_2 Catalase proximal active site signature. FdReripERvvHakGSG |
Chain | Residue | Details |
A | PHE45-GLY61 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | HIS56 | |
A | ASN129 | |
B | HIS56 | |
B | ASN129 | |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | BINDING: axial binding residue => ECO:0000250 |
Chain | Residue | Details |
A | TYR339 | |
B | TYR339 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1iph |
Chain | Residue | Details |
A | HIS56 | |
A | SER95 | |
A | ASN129 | |
site_id | CSA2 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1iph |
Chain | Residue | Details |
B | HIS56 | |
B | SER95 | |
B | ASN129 | |