1QWJ
The Crystal Structure of Murine CMP-5-N-Acetylneuraminic Acid Synthetase
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE NCC A 2002 |
| Chain | Residue |
| A | LEU48 |
| A | ALA123 |
| A | GLN141 |
| A | THR143 |
| A | GLY213 |
| A | TYR216 |
| A | HOH2020 |
| A | HOH2022 |
| A | HOH2024 |
| B | PHE176 |
| B | ARG199 |
| A | ALA49 |
| B | ARG201 |
| B | ARG202 |
| A | ARG50 |
| A | ASN60 |
| A | ARG109 |
| A | THR113 |
| A | SER118 |
| A | THR119 |
| A | SER120 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE NCC C 3002 |
| Chain | Residue |
| C | LEU48 |
| C | ALA49 |
| C | ARG50 |
| C | LYS59 |
| C | ASN60 |
| C | SER118 |
| C | GLN141 |
| C | THR143 |
| C | GLU211 |
| C | GLY213 |
| C | TYR216 |
| C | ASP247 |
| D | PHE176 |
| D | ARG199 |
| D | ARG201 |
| D | ARG202 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE NCC D 4002 |
| Chain | Residue |
| C | PHE176 |
| C | ARG201 |
| C | ARG202 |
| D | LEU48 |
| D | ALA49 |
| D | ARG50 |
| D | ASN60 |
| D | ARG109 |
| D | SER120 |
| D | GLN141 |
| D | THR143 |
| D | GLY213 |
| D | TYR216 |
| D | ASP247 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 24 |
| Details | Motif: {"description":"BC2 motif"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Active site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 24 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Omega-N-methylarginine","evidences":[{"source":"PubMed","id":"24129315","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
