Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000049 | molecular_function | tRNA binding |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0002161 | molecular_function | aminoacyl-tRNA deacylase activity |
| A | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| A | 0004822 | molecular_function | isoleucine-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006412 | biological_process | translation |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006428 | biological_process | isoleucyl-tRNA aminoacylation |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016874 | molecular_function | ligase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0106074 | biological_process | aminoacyl-tRNA metabolism involved in translational fidelity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN A 992 |
| Chain | Residue |
| A | ASP13 |
| A | HIS201 |
| A | HIS770 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE MRC A 993 |
| Chain | Residue |
| A | GLN558 |
| A | TRP562 |
| A | HIS585 |
| A | GLY586 |
| A | PHE587 |
| A | VAL588 |
| A | LYS595 |
| A | MET596 |
| A | SER597 |
| A | LYS598 |
| A | VAL603 |
| A | HOH1021 |
| A | PRO56 |
| A | HIS64 |
| A | GLY66 |
| A | HIS67 |
| A | GLU554 |
| A | ASP557 |
Functional Information from PROSITE/UniProt
| site_id | PS00178 |
| Number of Residues | 12 |
| Details | AA_TRNA_LIGASE_I Aminoacyl-transfer RNA synthetases class-I signature. PyaNGnLHMGHA |
| Chain | Residue | Details |
| A | PRO57-ALA68 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | Motif: {"description":"'HIGH' region"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Motif: {"description":"'KMSKS' region"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P56690","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"1QU2","evidenceCode":"ECO:0007744"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a8h |
| Chain | Residue | Details |
| A | LYS595 | |
| A | LYS598 | |
