Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SO4 A 202 |
| Chain | Residue |
| A | ARG25 |
| A | HOH382 |
| A | HOH429 |
| A | ARG78 |
| A | GLN190 |
| A | TYR191 |
| A | HOH230 |
| A | HOH231 |
| A | HOH232 |
| A | HOH380 |
| A | HOH381 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 A 203 |
| Chain | Residue |
| A | ALA1 |
| A | ASN2 |
| A | ARG183 |
| A | PRO186 |
| A | HOH207 |
| A | HOH273 |
| A | HOH342 |
| A | HOH343 |
| A | HOH398 |
| A | HOH399 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 204 |
| Chain | Residue |
| A | HIS36 |
| A | ARG89 |
| A | ARG140 |
| A | GLY141 |
| A | SER143 |
| A | GOL201 |
| A | HOH361 |
| A | HOH362 |
| A | HOH363 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 201 |
| Chain | Residue |
| A | HIS36 |
| A | ARG89 |
| A | TYR123 |
| A | GLU125 |
| A | SER159 |
| A | GLY160 |
| A | SO4204 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VTAGHC |
| Chain | Residue | Details |
| A | VAL32-CYS37 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. CMgrGDSGGSWI |
| Chain | Residue | Details |
| A | CYS137-ILE148 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system => ECO:0000250 |
| Chain | Residue | Details |
| A | HIS36 | |
| A | ASP63 | |
| A | SER143 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1ssx |
| Chain | Residue | Details |
| A | SER143 | |
| A | GLY141 | |
| A | ASP63 | |
| A | HIS36 | |
| A | SER159 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1ssx |
| Chain | Residue | Details |
| A | SER143 | |
| A | GLY141 | |
| A | ASP63 | |
| A | HIS36 | |
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 609 |
| Chain | Residue | Details |
| A | HIS36 | proton acceptor, proton donor |
| A | ASP63 | electrostatic stabiliser |
| A | GLY141 | electrostatic stabiliser |
| A | SER143 | electrostatic stabiliser |
| A | SER159 | electrostatic stabiliser |
