Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SO4 A 204 |
| Chain | Residue |
| A | ARG25 |
| A | HOH363 |
| A | HOH396 |
| A | ARG78 |
| A | GLN190 |
| A | TYR191 |
| A | HOH232 |
| A | HOH233 |
| A | HOH234 |
| A | HOH361 |
| A | HOH362 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 205 |
| Chain | Residue |
| A | ALA1 |
| A | ASN2 |
| A | ARG183 |
| A | PRO186 |
| A | HOH210 |
| A | HOH269 |
| A | HOH327 |
| A | HOH328 |
| A | HOH377 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 206 |
| Chain | Residue |
| A | HIS36 |
| A | ARG89 |
| A | ARG140 |
| A | GLY141 |
| A | SER143 |
| A | HOH343 |
| A | HOH344 |
| A | HOH345 |
| A | HOH419 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 207 |
| Chain | Residue |
| A | THR92 |
| A | ARG105 |
| A | HOH330 |
| A | HOH416 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 208 |
| Chain | Residue |
| A | ALA27 |
| A | THR28 |
| A | ARG129 |
| A | HOH228 |
| A | HOH292 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A 201 |
| Chain | Residue |
| A | HIS36 |
| A | ARG89 |
| A | TYR123 |
| A | GLU125 |
| A | SER159 |
| A | GLY160 |
| A | GOL203 |
| A | HOH280 |
| A | HOH332 |
| A | HOH398 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 202 |
| Chain | Residue |
| A | THR106 |
| A | THR107 |
| A | THR107 |
| A | TYR109 |
| A | GLN110 |
| A | CYS170 |
| A | HOH241 |
| A | HOH422 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 203 |
| Chain | Residue |
| A | HIS36 |
| A | ARG57 |
| A | ARG89 |
| A | GLU125 |
| A | GOL201 |
| A | HOH279 |
| A | HOH348 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VTAGHC |
| Chain | Residue | Details |
| A | VAL32-CYS37 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. CMgrGDSGGSWI |
| Chain | Residue | Details |
| A | CYS137-ILE148 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"evidenceCode":"ECO:0000250"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1ssx |
| Chain | Residue | Details |
| A | SER143 | |
| A | GLY141 | |
| A | ASP63 | |
| A | HIS36 | |
| A | SER159 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1ssx |
| Chain | Residue | Details |
| A | SER143 | |
| A | GLY141 | |
| A | ASP63 | |
| A | HIS36 | |
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 609 |
| Chain | Residue | Details |
| A | HIS36 | proton acceptor, proton donor |
| A | ASP63 | electrostatic stabiliser |
| A | GLY141 | electrostatic stabiliser |
| A | SER143 | electrostatic stabiliser |
| A | SER159 | electrostatic stabiliser |
