1QO5

Fructose 1,6-bisphosphate Aldolase from Human Liver Tissue

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004332	molecular_function	fructose-bisphosphate aldolase activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005815	cellular_component	microtubule organizing center
A	0005829	cellular_component	cytosol
A	0005856	cellular_component	cytoskeleton
A	0006000	biological_process	fructose metabolic process
A	0006001	biological_process	fructose catabolic process
A	0006094	biological_process	gluconeogenesis
A	0006096	biological_process	glycolytic process
A	0006116	biological_process	NADH oxidation
A	0008092	molecular_function	cytoskeletal protein binding
A	0016829	molecular_function	lyase activity
A	0030388	biological_process	fructose 1,6-bisphosphate metabolic process
A	0032781	biological_process	positive regulation of ATP-dependent activity
A	0034451	cellular_component	centriolar satellite
A	0042802	molecular_function	identical protein binding
A	0051117	molecular_function	ATPase binding
A	0060090	molecular_function	molecular adaptor activity
A	0061609	molecular_function	fructose-1-phosphate aldolase activity
A	0061624	biological_process	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate
A	0070061	molecular_function	fructose binding
A	0070062	cellular_component	extracellular exosome
A	0070072	biological_process	vacuolar proton-transporting V-type ATPase complex assembly
A	1905856	biological_process	negative regulation of pentose-phosphate shunt
B	0004332	molecular_function	fructose-bisphosphate aldolase activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005815	cellular_component	microtubule organizing center
B	0005829	cellular_component	cytosol
B	0005856	cellular_component	cytoskeleton
B	0006000	biological_process	fructose metabolic process
B	0006001	biological_process	fructose catabolic process
B	0006094	biological_process	gluconeogenesis
B	0006096	biological_process	glycolytic process
B	0006116	biological_process	NADH oxidation
B	0008092	molecular_function	cytoskeletal protein binding
B	0016829	molecular_function	lyase activity
B	0030388	biological_process	fructose 1,6-bisphosphate metabolic process
B	0032781	biological_process	positive regulation of ATP-dependent activity
B	0034451	cellular_component	centriolar satellite
B	0042802	molecular_function	identical protein binding
B	0051117	molecular_function	ATPase binding
B	0060090	molecular_function	molecular adaptor activity
B	0061609	molecular_function	fructose-1-phosphate aldolase activity
B	0061624	biological_process	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate
B	0070061	molecular_function	fructose binding
B	0070062	cellular_component	extracellular exosome
B	0070072	biological_process	vacuolar proton-transporting V-type ATPase complex assembly
B	1905856	biological_process	negative regulation of pentose-phosphate shunt
C	0004332	molecular_function	fructose-bisphosphate aldolase activity
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0005815	cellular_component	microtubule organizing center
C	0005829	cellular_component	cytosol
C	0005856	cellular_component	cytoskeleton
C	0006000	biological_process	fructose metabolic process
C	0006001	biological_process	fructose catabolic process
C	0006094	biological_process	gluconeogenesis
C	0006096	biological_process	glycolytic process
C	0006116	biological_process	NADH oxidation
C	0008092	molecular_function	cytoskeletal protein binding
C	0016829	molecular_function	lyase activity
C	0030388	biological_process	fructose 1,6-bisphosphate metabolic process
C	0032781	biological_process	positive regulation of ATP-dependent activity
C	0034451	cellular_component	centriolar satellite
C	0042802	molecular_function	identical protein binding
C	0051117	molecular_function	ATPase binding
C	0060090	molecular_function	molecular adaptor activity
C	0061609	molecular_function	fructose-1-phosphate aldolase activity
C	0061624	biological_process	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate
C	0070061	molecular_function	fructose binding
C	0070062	cellular_component	extracellular exosome
C	0070072	biological_process	vacuolar proton-transporting V-type ATPase complex assembly
C	1905856	biological_process	negative regulation of pentose-phosphate shunt
D	0004332	molecular_function	fructose-bisphosphate aldolase activity
D	0005515	molecular_function	protein binding
D	0005737	cellular_component	cytoplasm
D	0005815	cellular_component	microtubule organizing center
D	0005829	cellular_component	cytosol
D	0005856	cellular_component	cytoskeleton
D	0006000	biological_process	fructose metabolic process
D	0006001	biological_process	fructose catabolic process
D	0006094	biological_process	gluconeogenesis
D	0006096	biological_process	glycolytic process
D	0006116	biological_process	NADH oxidation
D	0008092	molecular_function	cytoskeletal protein binding
D	0016829	molecular_function	lyase activity
D	0030388	biological_process	fructose 1,6-bisphosphate metabolic process
D	0032781	biological_process	positive regulation of ATP-dependent activity
D	0034451	cellular_component	centriolar satellite
D	0042802	molecular_function	identical protein binding
D	0051117	molecular_function	ATPase binding
D	0060090	molecular_function	molecular adaptor activity
D	0061609	molecular_function	fructose-1-phosphate aldolase activity
D	0061624	biological_process	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate
D	0070061	molecular_function	fructose binding
D	0070062	cellular_component	extracellular exosome
D	0070072	biological_process	vacuolar proton-transporting V-type ATPase complex assembly
D	1905856	biological_process	negative regulation of pentose-phosphate shunt
E	0004332	molecular_function	fructose-bisphosphate aldolase activity
E	0005515	molecular_function	protein binding
E	0005737	cellular_component	cytoplasm
E	0005815	cellular_component	microtubule organizing center
E	0005829	cellular_component	cytosol
E	0005856	cellular_component	cytoskeleton
E	0006000	biological_process	fructose metabolic process
E	0006001	biological_process	fructose catabolic process
E	0006094	biological_process	gluconeogenesis
E	0006096	biological_process	glycolytic process
E	0006116	biological_process	NADH oxidation
E	0008092	molecular_function	cytoskeletal protein binding
E	0016829	molecular_function	lyase activity
E	0030388	biological_process	fructose 1,6-bisphosphate metabolic process
E	0032781	biological_process	positive regulation of ATP-dependent activity
E	0034451	cellular_component	centriolar satellite
E	0042802	molecular_function	identical protein binding
E	0051117	molecular_function	ATPase binding
E	0060090	molecular_function	molecular adaptor activity
E	0061609	molecular_function	fructose-1-phosphate aldolase activity
E	0061624	biological_process	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate
E	0070061	molecular_function	fructose binding
E	0070062	cellular_component	extracellular exosome
E	0070072	biological_process	vacuolar proton-transporting V-type ATPase complex assembly
E	1905856	biological_process	negative regulation of pentose-phosphate shunt
F	0004332	molecular_function	fructose-bisphosphate aldolase activity
F	0005515	molecular_function	protein binding
F	0005737	cellular_component	cytoplasm
F	0005815	cellular_component	microtubule organizing center
F	0005829	cellular_component	cytosol
F	0005856	cellular_component	cytoskeleton
F	0006000	biological_process	fructose metabolic process
F	0006001	biological_process	fructose catabolic process
F	0006094	biological_process	gluconeogenesis
F	0006096	biological_process	glycolytic process
F	0006116	biological_process	NADH oxidation
F	0008092	molecular_function	cytoskeletal protein binding
F	0016829	molecular_function	lyase activity
F	0030388	biological_process	fructose 1,6-bisphosphate metabolic process
F	0032781	biological_process	positive regulation of ATP-dependent activity
F	0034451	cellular_component	centriolar satellite
F	0042802	molecular_function	identical protein binding
F	0051117	molecular_function	ATPase binding
F	0060090	molecular_function	molecular adaptor activity
F	0061609	molecular_function	fructose-1-phosphate aldolase activity
F	0061624	biological_process	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate
F	0070061	molecular_function	fructose binding
F	0070062	cellular_component	extracellular exosome
F	0070072	biological_process	vacuolar proton-transporting V-type ATPase complex assembly
F	1905856	biological_process	negative regulation of pentose-phosphate shunt
G	0004332	molecular_function	fructose-bisphosphate aldolase activity
G	0005515	molecular_function	protein binding
G	0005737	cellular_component	cytoplasm
G	0005815	cellular_component	microtubule organizing center
G	0005829	cellular_component	cytosol
G	0005856	cellular_component	cytoskeleton
G	0006000	biological_process	fructose metabolic process
G	0006001	biological_process	fructose catabolic process
G	0006094	biological_process	gluconeogenesis
G	0006096	biological_process	glycolytic process
G	0006116	biological_process	NADH oxidation
G	0008092	molecular_function	cytoskeletal protein binding
G	0016829	molecular_function	lyase activity
G	0030388	biological_process	fructose 1,6-bisphosphate metabolic process
G	0032781	biological_process	positive regulation of ATP-dependent activity
G	0034451	cellular_component	centriolar satellite
G	0042802	molecular_function	identical protein binding
G	0051117	molecular_function	ATPase binding
G	0060090	molecular_function	molecular adaptor activity
G	0061609	molecular_function	fructose-1-phosphate aldolase activity
G	0061624	biological_process	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate
G	0070061	molecular_function	fructose binding
G	0070062	cellular_component	extracellular exosome
G	0070072	biological_process	vacuolar proton-transporting V-type ATPase complex assembly
G	1905856	biological_process	negative regulation of pentose-phosphate shunt
H	0004332	molecular_function	fructose-bisphosphate aldolase activity
H	0005515	molecular_function	protein binding
H	0005737	cellular_component	cytoplasm
H	0005815	cellular_component	microtubule organizing center
H	0005829	cellular_component	cytosol
H	0005856	cellular_component	cytoskeleton
H	0006000	biological_process	fructose metabolic process
H	0006001	biological_process	fructose catabolic process
H	0006094	biological_process	gluconeogenesis
H	0006096	biological_process	glycolytic process
H	0006116	biological_process	NADH oxidation
H	0008092	molecular_function	cytoskeletal protein binding
H	0016829	molecular_function	lyase activity
H	0030388	biological_process	fructose 1,6-bisphosphate metabolic process
H	0032781	biological_process	positive regulation of ATP-dependent activity
H	0034451	cellular_component	centriolar satellite
H	0042802	molecular_function	identical protein binding
H	0051117	molecular_function	ATPase binding
H	0060090	molecular_function	molecular adaptor activity
H	0061609	molecular_function	fructose-1-phosphate aldolase activity
H	0061624	biological_process	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate
H	0070061	molecular_function	fructose binding
H	0070062	cellular_component	extracellular exosome
H	0070072	biological_process	vacuolar proton-transporting V-type ATPase complex assembly
H	1905856	biological_process	negative regulation of pentose-phosphate shunt
I	0004332	molecular_function	fructose-bisphosphate aldolase activity
I	0005515	molecular_function	protein binding
I	0005737	cellular_component	cytoplasm
I	0005815	cellular_component	microtubule organizing center
I	0005829	cellular_component	cytosol
I	0005856	cellular_component	cytoskeleton
I	0006000	biological_process	fructose metabolic process
I	0006001	biological_process	fructose catabolic process
I	0006094	biological_process	gluconeogenesis
I	0006096	biological_process	glycolytic process
I	0006116	biological_process	NADH oxidation
I	0008092	molecular_function	cytoskeletal protein binding
I	0016829	molecular_function	lyase activity
I	0030388	biological_process	fructose 1,6-bisphosphate metabolic process
I	0032781	biological_process	positive regulation of ATP-dependent activity
I	0034451	cellular_component	centriolar satellite
I	0042802	molecular_function	identical protein binding
I	0051117	molecular_function	ATPase binding
I	0060090	molecular_function	molecular adaptor activity
I	0061609	molecular_function	fructose-1-phosphate aldolase activity
I	0061624	biological_process	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate
I	0070061	molecular_function	fructose binding
I	0070062	cellular_component	extracellular exosome
I	0070072	biological_process	vacuolar proton-transporting V-type ATPase complex assembly
I	1905856	biological_process	negative regulation of pentose-phosphate shunt
J	0004332	molecular_function	fructose-bisphosphate aldolase activity
J	0005515	molecular_function	protein binding
J	0005737	cellular_component	cytoplasm
J	0005815	cellular_component	microtubule organizing center
J	0005829	cellular_component	cytosol
J	0005856	cellular_component	cytoskeleton
J	0006000	biological_process	fructose metabolic process
J	0006001	biological_process	fructose catabolic process
J	0006094	biological_process	gluconeogenesis
J	0006096	biological_process	glycolytic process
J	0006116	biological_process	NADH oxidation
J	0008092	molecular_function	cytoskeletal protein binding
J	0016829	molecular_function	lyase activity
J	0030388	biological_process	fructose 1,6-bisphosphate metabolic process
J	0032781	biological_process	positive regulation of ATP-dependent activity
J	0034451	cellular_component	centriolar satellite
J	0042802	molecular_function	identical protein binding
J	0051117	molecular_function	ATPase binding
J	0060090	molecular_function	molecular adaptor activity
J	0061609	molecular_function	fructose-1-phosphate aldolase activity
J	0061624	biological_process	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate
J	0070061	molecular_function	fructose binding
J	0070062	cellular_component	extracellular exosome
J	0070072	biological_process	vacuolar proton-transporting V-type ATPase complex assembly
J	1905856	biological_process	negative regulation of pentose-phosphate shunt
K	0004332	molecular_function	fructose-bisphosphate aldolase activity
K	0005515	molecular_function	protein binding
K	0005737	cellular_component	cytoplasm
K	0005815	cellular_component	microtubule organizing center
K	0005829	cellular_component	cytosol
K	0005856	cellular_component	cytoskeleton
K	0006000	biological_process	fructose metabolic process
K	0006001	biological_process	fructose catabolic process
K	0006094	biological_process	gluconeogenesis
K	0006096	biological_process	glycolytic process
K	0006116	biological_process	NADH oxidation
K	0008092	molecular_function	cytoskeletal protein binding
K	0016829	molecular_function	lyase activity
K	0030388	biological_process	fructose 1,6-bisphosphate metabolic process
K	0032781	biological_process	positive regulation of ATP-dependent activity
K	0034451	cellular_component	centriolar satellite
K	0042802	molecular_function	identical protein binding
K	0051117	molecular_function	ATPase binding
K	0060090	molecular_function	molecular adaptor activity
K	0061609	molecular_function	fructose-1-phosphate aldolase activity
K	0061624	biological_process	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate
K	0070061	molecular_function	fructose binding
K	0070062	cellular_component	extracellular exosome
K	0070072	biological_process	vacuolar proton-transporting V-type ATPase complex assembly
K	1905856	biological_process	negative regulation of pentose-phosphate shunt
L	0004332	molecular_function	fructose-bisphosphate aldolase activity
L	0005515	molecular_function	protein binding
L	0005737	cellular_component	cytoplasm
L	0005815	cellular_component	microtubule organizing center
L	0005829	cellular_component	cytosol
L	0005856	cellular_component	cytoskeleton
L	0006000	biological_process	fructose metabolic process
L	0006001	biological_process	fructose catabolic process
L	0006094	biological_process	gluconeogenesis
L	0006096	biological_process	glycolytic process
L	0006116	biological_process	NADH oxidation
L	0008092	molecular_function	cytoskeletal protein binding
L	0016829	molecular_function	lyase activity
L	0030388	biological_process	fructose 1,6-bisphosphate metabolic process
L	0032781	biological_process	positive regulation of ATP-dependent activity
L	0034451	cellular_component	centriolar satellite
L	0042802	molecular_function	identical protein binding
L	0051117	molecular_function	ATPase binding
L	0060090	molecular_function	molecular adaptor activity
L	0061609	molecular_function	fructose-1-phosphate aldolase activity
L	0061624	biological_process	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate
L	0070061	molecular_function	fructose binding
L	0070062	cellular_component	extracellular exosome
L	0070072	biological_process	vacuolar proton-transporting V-type ATPase complex assembly
L	1905856	biological_process	negative regulation of pentose-phosphate shunt
M	0004332	molecular_function	fructose-bisphosphate aldolase activity
M	0005515	molecular_function	protein binding
M	0005737	cellular_component	cytoplasm
M	0005815	cellular_component	microtubule organizing center
M	0005829	cellular_component	cytosol
M	0005856	cellular_component	cytoskeleton
M	0006000	biological_process	fructose metabolic process
M	0006001	biological_process	fructose catabolic process
M	0006094	biological_process	gluconeogenesis
M	0006096	biological_process	glycolytic process
M	0006116	biological_process	NADH oxidation
M	0008092	molecular_function	cytoskeletal protein binding
M	0016829	molecular_function	lyase activity
M	0030388	biological_process	fructose 1,6-bisphosphate metabolic process
M	0032781	biological_process	positive regulation of ATP-dependent activity
M	0034451	cellular_component	centriolar satellite
M	0042802	molecular_function	identical protein binding
M	0051117	molecular_function	ATPase binding
M	0060090	molecular_function	molecular adaptor activity
M	0061609	molecular_function	fructose-1-phosphate aldolase activity
M	0061624	biological_process	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate
M	0070061	molecular_function	fructose binding
M	0070062	cellular_component	extracellular exosome
M	0070072	biological_process	vacuolar proton-transporting V-type ATPase complex assembly
M	1905856	biological_process	negative regulation of pentose-phosphate shunt
N	0004332	molecular_function	fructose-bisphosphate aldolase activity
N	0005515	molecular_function	protein binding
N	0005737	cellular_component	cytoplasm
N	0005815	cellular_component	microtubule organizing center
N	0005829	cellular_component	cytosol
N	0005856	cellular_component	cytoskeleton
N	0006000	biological_process	fructose metabolic process
N	0006001	biological_process	fructose catabolic process
N	0006094	biological_process	gluconeogenesis
N	0006096	biological_process	glycolytic process
N	0006116	biological_process	NADH oxidation
N	0008092	molecular_function	cytoskeletal protein binding
N	0016829	molecular_function	lyase activity
N	0030388	biological_process	fructose 1,6-bisphosphate metabolic process
N	0032781	biological_process	positive regulation of ATP-dependent activity
N	0034451	cellular_component	centriolar satellite
N	0042802	molecular_function	identical protein binding
N	0051117	molecular_function	ATPase binding
N	0060090	molecular_function	molecular adaptor activity
N	0061609	molecular_function	fructose-1-phosphate aldolase activity
N	0061624	biological_process	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate
N	0070061	molecular_function	fructose binding
N	0070062	cellular_component	extracellular exosome
N	0070072	biological_process	vacuolar proton-transporting V-type ATPase complex assembly
N	1905856	biological_process	negative regulation of pentose-phosphate shunt
O	0004332	molecular_function	fructose-bisphosphate aldolase activity
O	0005515	molecular_function	protein binding
O	0005737	cellular_component	cytoplasm
O	0005815	cellular_component	microtubule organizing center
O	0005829	cellular_component	cytosol
O	0005856	cellular_component	cytoskeleton
O	0006000	biological_process	fructose metabolic process
O	0006001	biological_process	fructose catabolic process
O	0006094	biological_process	gluconeogenesis
O	0006096	biological_process	glycolytic process
O	0006116	biological_process	NADH oxidation
O	0008092	molecular_function	cytoskeletal protein binding
O	0016829	molecular_function	lyase activity
O	0030388	biological_process	fructose 1,6-bisphosphate metabolic process
O	0032781	biological_process	positive regulation of ATP-dependent activity
O	0034451	cellular_component	centriolar satellite
O	0042802	molecular_function	identical protein binding
O	0051117	molecular_function	ATPase binding
O	0060090	molecular_function	molecular adaptor activity
O	0061609	molecular_function	fructose-1-phosphate aldolase activity
O	0061624	biological_process	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate
O	0070061	molecular_function	fructose binding
O	0070062	cellular_component	extracellular exosome
O	0070072	biological_process	vacuolar proton-transporting V-type ATPase complex assembly
O	1905856	biological_process	negative regulation of pentose-phosphate shunt
P	0004332	molecular_function	fructose-bisphosphate aldolase activity
P	0005515	molecular_function	protein binding
P	0005737	cellular_component	cytoplasm
P	0005815	cellular_component	microtubule organizing center
P	0005829	cellular_component	cytosol
P	0005856	cellular_component	cytoskeleton
P	0006000	biological_process	fructose metabolic process
P	0006001	biological_process	fructose catabolic process
P	0006094	biological_process	gluconeogenesis
P	0006096	biological_process	glycolytic process
P	0006116	biological_process	NADH oxidation
P	0008092	molecular_function	cytoskeletal protein binding
P	0016829	molecular_function	lyase activity
P	0030388	biological_process	fructose 1,6-bisphosphate metabolic process
P	0032781	biological_process	positive regulation of ATP-dependent activity
P	0034451	cellular_component	centriolar satellite
P	0042802	molecular_function	identical protein binding
P	0051117	molecular_function	ATPase binding
P	0060090	molecular_function	molecular adaptor activity
P	0061609	molecular_function	fructose-1-phosphate aldolase activity
P	0061624	biological_process	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate
P	0070061	molecular_function	fructose binding
P	0070062	cellular_component	extracellular exosome
P	0070072	biological_process	vacuolar proton-transporting V-type ATPase complex assembly
P	1905856	biological_process	negative regulation of pentose-phosphate shunt
Q	0004332	molecular_function	fructose-bisphosphate aldolase activity
Q	0005515	molecular_function	protein binding
Q	0005737	cellular_component	cytoplasm
Q	0005815	cellular_component	microtubule organizing center
Q	0005829	cellular_component	cytosol
Q	0005856	cellular_component	cytoskeleton
Q	0006000	biological_process	fructose metabolic process
Q	0006001	biological_process	fructose catabolic process
Q	0006094	biological_process	gluconeogenesis
Q	0006096	biological_process	glycolytic process
Q	0006116	biological_process	NADH oxidation
Q	0008092	molecular_function	cytoskeletal protein binding
Q	0016829	molecular_function	lyase activity
Q	0030388	biological_process	fructose 1,6-bisphosphate metabolic process
Q	0032781	biological_process	positive regulation of ATP-dependent activity
Q	0034451	cellular_component	centriolar satellite
Q	0042802	molecular_function	identical protein binding
Q	0051117	molecular_function	ATPase binding
Q	0060090	molecular_function	molecular adaptor activity
Q	0061609	molecular_function	fructose-1-phosphate aldolase activity
Q	0061624	biological_process	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate
Q	0070061	molecular_function	fructose binding
Q	0070062	cellular_component	extracellular exosome
Q	0070072	biological_process	vacuolar proton-transporting V-type ATPase complex assembly
Q	1905856	biological_process	negative regulation of pentose-phosphate shunt
R	0004332	molecular_function	fructose-bisphosphate aldolase activity
R	0005515	molecular_function	protein binding
R	0005737	cellular_component	cytoplasm
R	0005815	cellular_component	microtubule organizing center
R	0005829	cellular_component	cytosol
R	0005856	cellular_component	cytoskeleton
R	0006000	biological_process	fructose metabolic process
R	0006001	biological_process	fructose catabolic process
R	0006094	biological_process	gluconeogenesis
R	0006096	biological_process	glycolytic process
R	0006116	biological_process	NADH oxidation
R	0008092	molecular_function	cytoskeletal protein binding
R	0016829	molecular_function	lyase activity
R	0030388	biological_process	fructose 1,6-bisphosphate metabolic process
R	0032781	biological_process	positive regulation of ATP-dependent activity
R	0034451	cellular_component	centriolar satellite
R	0042802	molecular_function	identical protein binding
R	0051117	molecular_function	ATPase binding
R	0060090	molecular_function	molecular adaptor activity
R	0061609	molecular_function	fructose-1-phosphate aldolase activity
R	0061624	biological_process	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate
R	0070061	molecular_function	fructose binding
R	0070062	cellular_component	extracellular exosome
R	0070072	biological_process	vacuolar proton-transporting V-type ATPase complex assembly
R	1905856	biological_process	negative regulation of pentose-phosphate shunt

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 A 400

Chain	Residue
A	SER271
A	GLY272
A	TYR301
A	GLY302
A	ARG303
A	HOH505
A	HOH503
A	HOH501

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 D 400

Chain	Residue
D	SER271
D	GLY272
D	SER300
D	GLY302
D	ARG303
D	LEU270

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 E 400

Chain	Residue
E	LYS229
E	LEU270
E	SER271
E	GLY272
E	TYR301
E	GLY302
E	ARG303

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 G 400

Chain	Residue
G	LEU270
G	SER271
G	GLY272
G	GLY302
G	ARG303

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 J 400

Chain	Residue
J	SER271
J	GLY272
J	TYR301
J	GLY302
J	ARG303

---

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 K 400

Chain	Residue
K	LYS229
K	LEU270
K	SER271
K	GLY272
K	TYR301
K	GLY302
K	ARG303

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 N 400

Chain	Residue
P	LYS229
P	LEU270
P	SER271
P	GLY272
P	GLY302
P	ARG303

---

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 R 400

Chain	Residue
R	LYS229
R	SER271
R	GLY272
R	GLY302
R	ARG303

---

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 S 1

Chain	Residue
A	GLN202
A	THR254
A	ARG258
D	GLN9
D	LYS12

---

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 S 2

Chain	Residue
M	GLN202
M	THR254
M	ARG258
M	HOH528
P	GLN9

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 S 3

Chain	Residue
F	GLN202
F	ARG258
G	GLN9
G	LYS12

---

site_id	BC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 S 4

Chain	Residue
N	LYS12
O	GLN202
O	ARG258

---

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 S 5

Chain	Residue
F	GLN9
F	LYS12
G	GLN202
G	ARG258

---

site_id	BC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 S 6

Chain	Residue
R	GLN9
R	LYS12
R	GLN202
R	THR254
R	ARG258

---

site_id	BC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 S 7

Chain	Residue
M	GLN9
M	LYS12
P	GLN202
P	THR254
P	ARG258
P	HOH549

---

Functional Information from PROSITE/UniProt

site_id	PS00158
Number of Residues	11
Details	ALDOLASE_CLASS_I Fructose-bisphosphate aldolase class-I active site. VyLEGtLLKPN

Chain	Residue	Details
A	VAL221-ASN231

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	18
Details	ACT_SITE: Proton acceptor => ECO:0000250|UniProtKB:P00883

Chain	Residue	Details
A	PRO188
J	PRO188
K	PRO188
L	PRO188
M	PRO188
N	PRO188
O	PRO188
P	PRO188
Q	PRO188
R	PRO188
B	PRO188
C	PRO188
D	PRO188
E	PRO188
F	PRO188
G	PRO188
H	PRO188
I	PRO188

---

site_id	SWS_FT_FI2
Number of Residues	18
Details	ACT_SITE: Schiff-base intermediate with dihydroxyacetone-P => ECO:0000250|UniProtKB:P00883

Chain	Residue	Details
A	PRO230
J	PRO230
K	PRO230
L	PRO230
M	PRO230
N	PRO230
O	PRO230
P	PRO230
Q	PRO230
R	PRO230
B	PRO230
C	PRO230
D	PRO230
E	PRO230
F	PRO230
G	PRO230
H	PRO230
I	PRO230

---

site_id	SWS_FT_FI3
Number of Residues	54
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P00883

Chain	Residue	Details
A	LEU43
D	LEU43
D	GLY272
D	ALA304
E	LEU43
E	GLY272
E	ALA304
F	LEU43
F	GLY272
F	ALA304
G	LEU43
A	GLY272
G	GLY272
G	ALA304
H	LEU43
H	GLY272
H	ALA304
I	LEU43
I	GLY272
I	ALA304
J	LEU43
J	GLY272
A	ALA304
J	ALA304
K	LEU43
K	GLY272
K	ALA304
L	LEU43
L	GLY272
L	ALA304
M	LEU43
M	GLY272
M	ALA304
B	LEU43
N	LEU43
N	GLY272
N	ALA304
O	LEU43
O	GLY272
O	ALA304
P	LEU43
P	GLY272
P	ALA304
Q	LEU43
B	GLY272
Q	GLY272
Q	ALA304
R	LEU43
R	GLY272
R	ALA304
B	ALA304
C	LEU43
C	GLY272
C	ALA304

---

site_id	SWS_FT_FI4
Number of Residues	18
Details	MOD_RES: N-acetylalanine => ECO:0000250|UniProtKB:Q91Y97

Chain	Residue	Details
A	HIS2
J	HIS2
K	HIS2
L	HIS2
M	HIS2
N	HIS2
O	HIS2
P	HIS2
Q	HIS2
R	HIS2
B	HIS2
C	HIS2
D	HIS2
E	HIS2
F	HIS2
G	HIS2
H	HIS2
I	HIS2

---

site_id	SWS_FT_FI5
Number of Residues	54
Details	MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:Q91Y97

Chain	Residue	Details
A	LYS13
D	LYS13
D	GLU121
D	ALA317
E	LYS13
E	GLU121
E	ALA317
F	LYS13
F	GLU121
F	ALA317
G	LYS13
A	GLU121
G	GLU121
G	ALA317
H	LYS13
H	GLU121
H	ALA317
I	LYS13
I	GLU121
I	ALA317
J	LYS13
J	GLU121
A	ALA317
J	ALA317
K	LYS13
K	GLU121
K	ALA317
L	LYS13
L	GLU121
L	ALA317
M	LYS13
M	GLU121
M	ALA317
B	LYS13
N	LYS13
N	GLU121
N	ALA317
O	LYS13
O	GLU121
O	ALA317
P	LYS13
P	GLU121
P	ALA317
Q	LYS13
B	GLU121
Q	GLU121
Q	ALA317
R	LYS13
R	GLU121
R	ALA317
B	ALA317
C	LYS13
C	GLU121
C	ALA317

---

site_id	SWS_FT_FI6
Number of Residues	108
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
A	VAL36
B	GLY272
Q	GLY272
Q	GLU276
Q	ALA309
R	VAL36
R	GLN89
R	GLU132
R	GLY272
R	GLU276
R	ALA309
B	GLU276
B	ALA309
C	VAL36
C	GLN89
C	GLU132
C	GLY272
C	GLU276
C	ALA309
D	VAL36
A	GLN89
D	GLN89
D	GLU132
D	GLY272
D	GLU276
D	ALA309
E	VAL36
E	GLN89
E	GLU132
E	GLY272
E	GLU276
A	GLU132
E	ALA309
F	VAL36
F	GLN89
F	GLU132
F	GLY272
F	GLU276
F	ALA309
G	VAL36
G	GLN89
G	GLU132
A	GLY272
G	GLY272
G	GLU276
G	ALA309
H	VAL36
H	GLN89
H	GLU132
H	GLY272
H	GLU276
H	ALA309
I	VAL36
A	GLU276
I	GLN89
I	GLU132
I	GLY272
I	GLU276
I	ALA309
J	VAL36
J	GLN89
J	GLU132
J	GLY272
J	GLU276
A	ALA309
J	ALA309
K	VAL36
K	GLN89
K	GLU132
K	GLY272
K	GLU276
K	ALA309
L	VAL36
L	GLN89
L	GLU132
B	VAL36
L	GLY272
L	GLU276
L	ALA309
M	VAL36
M	GLN89
M	GLU132
M	GLY272
M	GLU276
M	ALA309
N	VAL36
B	GLN89
N	GLN89
N	GLU132
N	GLY272
N	GLU276
N	ALA309
O	VAL36
O	GLN89
O	GLU132
O	GLY272
O	GLU276
B	GLU132
O	ALA309
P	VAL36
P	GLN89
P	GLU132
P	GLY272
P	GLU276
P	ALA309
Q	VAL36
Q	GLN89
Q	GLU132

---

site_id	SWS_FT_FI7
Number of Residues	36
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:24275569

Chain	Residue	Details
A	MET39
E	ASN119
F	MET39
F	ASN119
G	MET39
G	ASN119
H	MET39
H	ASN119
I	MET39
I	ASN119
J	MET39
A	ASN119
J	ASN119
K	MET39
K	ASN119
L	MET39
L	ASN119
M	MET39
M	ASN119
N	MET39
N	ASN119
O	MET39
B	MET39
O	ASN119
P	MET39
P	ASN119
Q	MET39
Q	ASN119
R	MET39
R	ASN119
B	ASN119
C	MET39
C	ASN119
D	MET39
D	ASN119
E	MET39

---

site_id	SWS_FT_FI8
Number of Residues	36
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P00884

Chain	Residue	Details
A	PHE299
E	TYR301
F	PHE299
F	TYR301
G	PHE299
G	TYR301
H	PHE299
H	TYR301
I	PHE299
I	TYR301
J	PHE299
A	TYR301
J	TYR301
K	PHE299
K	TYR301
L	PHE299
L	TYR301
M	PHE299
M	TYR301
N	PHE299
N	TYR301
O	PHE299
B	PHE299
O	TYR301
P	PHE299
P	TYR301
Q	PHE299
Q	TYR301
R	PHE299
R	TYR301
B	TYR301
C	PHE299
C	TYR301
D	PHE299
D	TYR301
E	PHE299

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1ald

Chain	Residue	Details
A	GLU187
A	LYS229
A	ASP33

---

site_id	CSA10
Number of Residues	3
Details	Annotated By Reference To The Literature 1ald

Chain	Residue	Details
J	GLU187
J	LYS229
J	ASP33

---

site_id	CSA11
Number of Residues	3
Details	Annotated By Reference To The Literature 1ald

Chain	Residue	Details
K	GLU187
K	LYS229
K	ASP33

---

site_id	CSA12
Number of Residues	3
Details	Annotated By Reference To The Literature 1ald

Chain	Residue	Details
L	GLU187
L	LYS229
L	ASP33

---

site_id	CSA13
Number of Residues	3
Details	Annotated By Reference To The Literature 1ald

Chain	Residue	Details
M	GLU187
M	LYS229
M	ASP33

---

site_id	CSA14
Number of Residues	3
Details	Annotated By Reference To The Literature 1ald

Chain	Residue	Details
N	GLU187
N	LYS229
N	ASP33

---

site_id	CSA15
Number of Residues	3
Details	Annotated By Reference To The Literature 1ald

Chain	Residue	Details
O	GLU187
O	LYS229
O	ASP33

---

site_id	CSA16
Number of Residues	3
Details	Annotated By Reference To The Literature 1ald

Chain	Residue	Details
P	GLU187
P	LYS229
P	ASP33

---

site_id	CSA17
Number of Residues	3
Details	Annotated By Reference To The Literature 1ald

Chain	Residue	Details
Q	GLU187
Q	LYS229
Q	ASP33

---

site_id	CSA18
Number of Residues	3
Details	Annotated By Reference To The Literature 1ald

Chain	Residue	Details
R	GLU187
R	LYS229
R	ASP33

---

site_id	CSA2
Number of Residues	3
Details	Annotated By Reference To The Literature 1ald

Chain	Residue	Details
B	GLU187
B	LYS229
B	ASP33

---

site_id	CSA3
Number of Residues	3
Details	Annotated By Reference To The Literature 1ald

Chain	Residue	Details
C	GLU187
C	LYS229
C	ASP33

---

site_id	CSA4
Number of Residues	3
Details	Annotated By Reference To The Literature 1ald

Chain	Residue	Details
D	GLU187
D	LYS229
D	ASP33

---

site_id	CSA5
Number of Residues	3
Details	Annotated By Reference To The Literature 1ald

Chain	Residue	Details
E	GLU187
E	LYS229
E	ASP33

---

site_id	CSA6
Number of Residues	3
Details	Annotated By Reference To The Literature 1ald

Chain	Residue	Details
F	GLU187
F	LYS229
F	ASP33

---

site_id	CSA7
Number of Residues	3
Details	Annotated By Reference To The Literature 1ald

Chain	Residue	Details
G	GLU187
G	LYS229
G	ASP33

---

site_id	CSA8
Number of Residues	3
Details	Annotated By Reference To The Literature 1ald

Chain	Residue	Details
H	GLU187
H	LYS229
H	ASP33

---

site_id	CSA9
Number of Residues	3
Details	Annotated By Reference To The Literature 1ald

Chain	Residue	Details
I	GLU187
I	LYS229
I	ASP33

---