1QHZ

NATIVE TETRAGONAL STRUCTURE OF THE ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHAERENS

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
A	0005975	biological_process	carbohydrate metabolic process
A	0071704	biological_process	organic substance metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CA A 400

Chain	Residue
A	HOH548
A	HOH568
A	HOH577
A	HOH579
A	HOH587
A	HOH717
A	HOH726

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 401

Chain	Residue
A	GLU157
A	ASP243
A	HOH531
A	HOH640
A	HOH681
A	HOH686

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 402

Chain	Residue
A	GLY127
A	ASP166
A	ASN168
A	ASN169
A	HOH512
A	HOH557

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA A 403

Chain	Residue
A	ASP120
A	GLU124
A	GLU124
A	HOH454

---

site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CA A 404

Chain	Residue
A	GLU139
A	GLU228
A	HOH416
A	HOH436
A	HOH566
A	HOH584
A	HOH626

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA A 405

Chain	Residue
A	ASN256
A	HOH552
A	HOH567
A	HOH597
A	HOH648

---

site_id	ACI
Number of Residues	1
Details	ACID/BASE

Chain	Residue
A	GLU139

---

site_id	NUC
Number of Residues	1
Details	NUCLEOPHILE

Chain	Residue
A	GLU228

---

Functional Information from PROSITE/UniProt

site_id	PS00659
Number of Residues	10
Details	GLYCOSYL_HYDROL_F5 Glycosyl hydrolases family 5 signature. VIYEIANEPN

Chain	Residue	Details
A	VAL132-ASN141

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton donor => ECO:0000305|PubMed:12595701, ECO:0000305|PubMed:9485319, ECO:0000305|PubMed:9718293, ECO:0000305|DOI:10.1021/ja984238n

Chain	Residue	Details
A	GLU139

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: Nucleophile => ECO:0000269|PubMed:12595701, ECO:0000269|PubMed:9485319, ECO:0000269|PubMed:9718293, ECO:0000269|DOI:10.1021/ja984238n, ECO:0007744|PDB:1H11, ECO:0007744|PDB:1QI2, ECO:0007744|PDB:5A3H, ECO:0007744|PDB:6A3H, ECO:0007744|PDB:8A3H

Chain	Residue	Details
A	GLU228

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:12595701, ECO:0000269|PubMed:9485319, ECO:0000269|PubMed:9718293, ECO:0007744|PDB:1HF6, ECO:0007744|PDB:2A3H, ECO:0007744|PDB:3A3H

Chain	Residue	Details
A	HIS35

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:12595701, ECO:0000269|PubMed:9485319, ECO:0000269|PubMed:9718293, ECO:0007744|PDB:1HF6, ECO:0007744|PDB:1QI0, ECO:0007744|PDB:2A3H, ECO:0007744|PDB:3A3H

Chain	Residue	Details
A	TYR66
A	LYS267
A	TRP39

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:12595701, ECO:0000269|PubMed:9718293, ECO:0000269|DOI:10.1021/ja984238n, ECO:0007744|PDB:1HF6, ECO:0007744|PDB:3A3H

Chain	Residue	Details
A	HIS101

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:12595701, ECO:0000269|PubMed:9718293, ECO:0007744|PDB:1HF6, ECO:0007744|PDB:3A3H

Chain	Residue	Details
A	ALA234
A	TYR202

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:12595701, ECO:0000269|PubMed:9485319, ECO:0000269|PubMed:9718293, ECO:0000269|DOI:10.1021/ja984238n, ECO:0007744|PDB:1H5V, ECO:0007744|PDB:1HF6, ECO:0007744|PDB:1QI0, ECO:0007744|PDB:2A3H, ECO:0007744|PDB:3A3H, ECO:0007744|PDB:8A3H

Chain	Residue	Details
A	TRP262

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