1QH9

ENZYME-PRODUCT COMPLEX OF L-2-HALOACID DEHALOGENASE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016787	molecular_function	hydrolase activity
A	0018784	molecular_function	(S)-2-haloacid dehalogenase activity
A	0019120	molecular_function	hydrolase activity, acting on acid halide bonds, in C-halide compounds

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE LAC A 300

Chain	Residue
A	ASP10
A	LEU11
A	TYR12
A	ARG41
A	SER118
A	ASN119
A	LYS151

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Nucleophile => ECO:0000269|PubMed:9614112, ECO:0000305|PubMed:7490277

Chain	Residue	Details
A	ASP10

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:9614112, ECO:0000269|Ref.5, ECO:0007744|PDB:1QH9, ECO:0007744|PDB:1ZRM, ECO:0007744|PDB:1ZRN

Chain	Residue	Details
A	LEU11
A	SER118

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site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000305|PubMed:9614112, ECO:0007744|PDB:1ZRM, ECO:0007744|PDB:1ZRN

Chain	Residue	Details
A	ARG41

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site_id	SWS_FT_FI4
Number of Residues	3
Details	SITE: Important for catalytic activity => ECO:0000269|PubMed:7490277, ECO:0000305|PubMed:9614112

Chain	Residue	Details
A	THR14
A	LYS151
A	TYR157

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details

Chain	Residue	Details
A	SER118
A	ASP10
A	ASP180
A	ARG41

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