Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0005764 | cellular_component | lysosome |
| A | 0005773 | cellular_component | vacuole |
| A | 0006508 | biological_process | proteolysis |
| A | 0006629 | biological_process | lipid metabolic process |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0005764 | cellular_component | lysosome |
| B | 0005773 | cellular_component | vacuole |
| B | 0006508 | biological_process | proteolysis |
| B | 0006629 | biological_process | lipid metabolic process |
| C | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| C | 0005764 | cellular_component | lysosome |
| C | 0005773 | cellular_component | vacuole |
| C | 0006508 | biological_process | proteolysis |
| C | 0006629 | biological_process | lipid metabolic process |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. VIFDTGSSNLWV |
| Chain | Residue | Details |
| A | VAL33-VAL44 | |
| A | ALA220-GLY231 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | ACT_SITE: |
| Chain | Residue | Details |
| A | ASP36 | |
| A | ASP223 | |
| B | ASP36 | |
| B | ASP223 | |
| C | ASP36 | |
| C | ASP223 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | SITE: Cleavage |
| Chain | Residue | Details |
| A | ARG64 | |
| A | GLY251 | |
| B | ARG64 | |
| B | GLY251 | |
| C | ARG64 | |
| C | GLY251 | |
| Chain | Residue | Details |
| A | ASN86 | |
| B | ASN86 | |
| C | ASN86 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | THR226 | |
| A | ASP223 | |
| A | SER39 | |
| A | ASP36 | |
| site_id | CSA10 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | TYR80 | |
| A | ASP223 | |
| A | SER39 | |
| A | ASP36 | |
| site_id | CSA11 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | TYR80 | |
| B | ASP223 | |
| B | SER39 | |
| B | ASP36 | |
| site_id | CSA12 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| C | TYR80 | |
| C | ASP223 | |
| C | SER39 | |
| C | ASP36 | |
| site_id | CSA13 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | THR226 | |
| A | ASP223 | |
| A | THR37 | |
| A | ASP36 | |
| site_id | CSA14 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | THR226 | |
| B | ASP223 | |
| B | THR37 | |
| B | ASP36 | |
| site_id | CSA15 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| C | THR226 | |
| C | ASP223 | |
| C | THR37 | |
| C | ASP36 | |
| site_id | CSA16 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP223 | |
| A | ASP36 | |
| site_id | CSA17 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | ASP223 | |
| B | ASP36 | |
| site_id | CSA18 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| C | ASP223 | |
| C | ASP36 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | THR226 | |
| B | ASP223 | |
| B | SER39 | |
| B | ASP36 | |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| C | THR226 | |
| C | ASP223 | |
| C | SER39 | |
| C | ASP36 | |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | SER224 | |
| A | ASP223 | |
| A | THR37 | |
| A | ASP36 | |
| site_id | CSA5 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | SER224 | |
| B | ASP223 | |
| B | THR37 | |
| B | ASP36 | |
| site_id | CSA6 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| C | SER224 | |
| C | ASP223 | |
| C | THR37 | |
| C | ASP36 | |
| site_id | CSA7 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP223 | |
| A | SER39 | |
| A | ASP36 | |
| site_id | CSA8 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | ASP223 | |
| B | SER39 | |
| B | ASP36 | |
| site_id | CSA9 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| C | ASP223 | |
| C | SER39 | |
| C | ASP36 | |
