Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005542 | molecular_function | folic acid binding |
| A | 0016740 | molecular_function | transferase activity |
| B | 0005542 | molecular_function | folic acid binding |
| B | 0016740 | molecular_function | transferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE FON A 330 |
| Chain | Residue |
| A | ASN10 |
| A | TYR126 |
| A | ARG142 |
| A | ARG179 |
| A | ASN186 |
| A | TRP224 |
| A | LEU226 |
| A | GLU228 |
| A | GLN233 |
| A | ASN237 |
| A | GLN268 |
| A | ASP39 |
| A | VAL270 |
| A | GOL480 |
| A | HOH588 |
| A | HOH667 |
| A | HOH807 |
| A | HOH829 |
| A | SER40 |
| A | GLY41 |
| A | THR44 |
| A | ARG46 |
| A | VAL48 |
| A | HIS82 |
| A | PRO92 |
| site_id | AC2 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE FON B 2330 |
| Chain | Residue |
| B | HOH528 |
| B | HOH566 |
| B | HOH618 |
| B | HOH909 |
| B | HOH1122 |
| B | HOH1131 |
| B | HOH1237 |
| B | ASN2010 |
| B | ASP2039 |
| B | SER2040 |
| B | GLY2041 |
| B | THR2044 |
| B | ARG2046 |
| B | VAL2048 |
| B | HIS2082 |
| B | TYR2126 |
| B | LEU2138 |
| B | ARG2142 |
| B | ARG2179 |
| B | LEU2182 |
| B | ASN2186 |
| B | TRP2224 |
| B | LEU2226 |
| B | GLU2228 |
| B | ASN2237 |
| B | GLN2268 |
| B | VAL2270 |
| B | GOL2480 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A 480 |
| Chain | Residue |
| A | HIS82 |
| A | ARG142 |
| A | GLN220 |
| A | ALA221 |
| A | ILE222 |
| A | SER235 |
| A | THR236 |
| A | ASN237 |
| A | FON330 |
| A | HOH1228 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 2480 |
| Chain | Residue |
| B | HOH902 |
| B | HOH909 |
| B | HIS2082 |
| B | ARG2142 |
| B | SER2235 |
| B | THR2236 |
| B | ASN2237 |
| B | FON2330 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"For formimidoyltransferase activity","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 144 |
| Details | Region: {"description":"Formiminotransferase C-subdomain","evidences":[{"evidenceCode":"ECO:0000250"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | a catalytic site defined by CSA, PubMed 10673422 |
| Chain | Residue | Details |
| A | HIS82 | |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | a catalytic site defined by CSA, PubMed 10673422 |
| Chain | Residue | Details |
| B | HIS2082 | |
| site_id | MCSA1 |
| Number of Residues | 1 |
| Details | M-CSA 887 |
| Chain | Residue | Details |
| A | HIS82 | proton shuttle (general acid/base) |
| site_id | MCSA2 |
| Number of Residues | 1 |
| Details | M-CSA 887 |
| Chain | Residue | Details |
| B | HIS2082 | proton shuttle (general acid/base) |
1QD1
