1QCI

LOW TEMPERATURE STRUCTURE OF POKEWEED ANTIVIRAL PROTEIN COMPLEXED WITH ADENINE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016787	molecular_function	hydrolase activity
A	0017148	biological_process	negative regulation of translation
A	0030598	molecular_function	rRNA N-glycosylase activity
A	0035821	biological_process	modulation of process of another organism
A	0051607	biological_process	defense response to virus
A	0090729	molecular_function	toxin activity
B	0016787	molecular_function	hydrolase activity
B	0017148	biological_process	negative regulation of translation
B	0030598	molecular_function	rRNA N-glycosylase activity
B	0035821	biological_process	modulation of process of another organism
B	0051607	biological_process	defense response to virus
B	0090729	molecular_function	toxin activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE ADE B 901

Chain	Residue
B	LEU71
B	TYR72
B	VAL73
B	SER121
B	ILE171
B	ARG179
B	HOH904

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ADE A 902

Chain	Residue
A	SER121
A	ILE171
A	ARG179
A	HOH908
A	TYR72
A	VAL73

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Functional Information from PROSITE/UniProt

site_id	PS00275
Number of Residues	17
Details	SHIGA_RICIN Shiga/ricin ribosomal inactivating toxins active site signature. IqMVsEAARFKyIEnqV

Chain	Residue	Details
A	ILE171-VAL187

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	ACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:P84531

Chain	Residue	Details
A	ILE93
A	ILE144
A	PRO197
A	LYS200
B	ILE93
B	ILE144
B	PRO197
B	LYS200

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:10493577, ECO:0000269|PubMed:10595542, ECO:0000269|PubMed:8411176, ECO:0007744|PDB:1D6A, ECO:0007744|PDB:1PAG, ECO:0007744|PDB:1QCI, ECO:0007744|PDB:1QCJ

Chain	Residue	Details
A	SER94
B	SER94

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site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:10493577, ECO:0000269|PubMed:10595542, ECO:0000269|PubMed:8411176, ECO:0007744|PDB:1D6A, ECO:0007744|PDB:1PAG, ECO:0007744|PDB:1QCJ

Chain	Residue	Details
A	ILE142
B	ILE142

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site_id	SWS_FT_FI4
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:10493577, ECO:0007744|PDB:1QCJ

Chain	Residue	Details
A	ASN196
B	ASN196

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site_id	SWS_FT_FI5
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:10493577, ECO:0000269|PubMed:10595542, ECO:0000269|PubMed:8411176, ECO:0007744|PDB:1D6A, ECO:0007744|PDB:1PAG, ECO:0007744|PDB:1QCI

Chain	Residue	Details
A	LYS200
B	LYS200

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1abr

Chain	Residue	Details
A	ARG179
A	GLU176

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site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1abr

Chain	Residue	Details
B	ARG179
B	GLU176

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