Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000154 | biological_process | rRNA modification |
A | 0000179 | molecular_function | rRNA (adenine-N6,N6-)-dimethyltransferase activity |
A | 0003723 | molecular_function | RNA binding |
A | 0005829 | cellular_component | cytosol |
A | 0008168 | molecular_function | methyltransferase activity |
A | 0031167 | biological_process | rRNA methylation |
A | 0032259 | biological_process | methylation |
A | 0046677 | biological_process | response to antibiotic |
A | 0052910 | molecular_function | 23S rRNA (adenine(2085)-N(6))-dimethyltransferase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 18 |
Details | BINDING SITE FOR RESIDUE SAM A 245 |
Chain | Residue |
A | ASN11 |
A | GLU59 |
A | ILE60 |
A | LEU64 |
A | LYS83 |
A | ASP84 |
A | ILE85 |
A | ASN101 |
A | PRO103 |
A | ILE106 |
A | PHE12 |
A | ILE13 |
A | GLU36 |
A | GLY38 |
A | SER39 |
A | GLY40 |
A | PHE44 |
A | ILE58 |
Functional Information from PROSITE/UniProt
site_id | PS01131 |
Number of Residues | 28 |
Details | RRNA_A_DIMETH Ribosomal RNA adenine dimethylases signature. IFEiGSGkGhFTlelVqrcnf...VtAIEiD |
Chain | Residue | Details |
A | ILE34-ASP61 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 6 |
Details | BINDING: |
Chain | Residue | Details |
A | ASN11 | |
A | ILE13 | |
A | GLY38 | |
A | GLU59 | |
A | ASP84 | |
A | ASN101 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1qam |
Chain | Residue | Details |
A | GLY38 | |
A | ASN101 | |
A | GLU59 | |
site_id | MCSA1 |
Number of Residues | 5 |
Details | M-CSA 898 |
Chain | Residue | Details |
A | GLY38 | activator, electrostatic stabiliser |
A | GLU59 | activator, electrostatic stabiliser |
A | ASN101 | activator, electrostatic stabiliser |
A | TYR104 | activator, electrostatic stabiliser |
A | PHE163 | activator, electrostatic stabiliser |