1Q9E

RNase T1 variant with adenine specificity

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001411	cellular_component	hyphal tip
A	0003723	molecular_function	RNA binding
A	0004519	molecular_function	endonuclease activity
A	0004540	molecular_function	RNA nuclease activity
A	0008150	biological_process	biological_process
A	0016829	molecular_function	lyase activity
A	0030428	cellular_component	cell septum
A	0046589	molecular_function	ribonuclease T1 activity
B	0001411	cellular_component	hyphal tip
B	0003723	molecular_function	RNA binding
B	0004519	molecular_function	endonuclease activity
B	0004540	molecular_function	RNA nuclease activity
B	0008150	biological_process	biological_process
B	0016829	molecular_function	lyase activity
B	0030428	cellular_component	cell septum
B	0046589	molecular_function	ribonuclease T1 activity
C	0001411	cellular_component	hyphal tip
C	0003723	molecular_function	RNA binding
C	0004519	molecular_function	endonuclease activity
C	0004540	molecular_function	RNA nuclease activity
C	0008150	biological_process	biological_process
C	0016829	molecular_function	lyase activity
C	0030428	cellular_component	cell septum
C	0046589	molecular_function	ribonuclease T1 activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE TRS A 301

Chain	Residue
A	TYR38
A	HIS40
A	GLU58
A	ARG77
A	HIS92
A	PHE100
C	ASN83

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site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE TRS C 302

Chain	Residue
C	TYR38
C	HIS40
C	GLU58
C	ARG77
C	HIS92
C	PHE100
A	ASN83
C	ASN36

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	ACT_SITE: ACT_SITE => ECO:0000269|PubMed:2844811

Chain	Residue	Details
A	ASP66
B	ASP66
C	ASP66

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site_id	SWS_FT_FI2
Number of Residues	3
Details	ACT_SITE: Proton acceptor => ECO:0000269|PubMed:2844811

Chain	Residue	Details
A	ASN84
B	ASN84
C	ASN84

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues	4
Details	M-CSA 414

Chain	Residue	Details
A	SER64	electrostatic stabiliser
A	ASP66	proton shuttle (general acid/base)
A	ASN84	proton shuttle (general acid/base)
A	CYS103	electrostatic stabiliser

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site_id	MCSA2
Number of Residues	4
Details	M-CSA 414

Chain	Residue	Details
B	SER64	electrostatic stabiliser
B	ASP66	proton shuttle (general acid/base)
B	ASN84	proton shuttle (general acid/base)
B	CYS103	electrostatic stabiliser

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site_id	MCSA3
Number of Residues	4
Details	M-CSA 414

Chain	Residue	Details
C	SER64	electrostatic stabiliser
C	ASP66	proton shuttle (general acid/base)
C	ASN84	proton shuttle (general acid/base)
C	CYS103	electrostatic stabiliser

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