Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 743 |
| Chain | Residue |
| A | ASN299 |
| A | ATP485 |
| A | ASP550 |
| A | MG744 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG A 744 |
| Chain | Residue |
| A | ATP485 |
| A | ASP550 |
| A | MG743 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NI B 743 |
| Chain | Residue |
| B | TYR153 |
| B | HIS234 |
| B | HIS145 |
| B | GLU151 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 745 |
| Chain | Residue |
| A | TYR153 |
| A | LYS154 |
| A | ASP155 |
| A | ASN233 |
| A | HIS234 |
| A | LYS235 |
| A | HOH776 |
| A | HOH796 |
| A | HOH798 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 744 |
| Chain | Residue |
| B | LYS154 |
| B | ASP155 |
| B | PHE232 |
| B | ASN233 |
| B | HIS234 |
| B | LYS235 |
| B | HOH752 |
| site_id | AC6 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE ATP A 485 |
| Chain | Residue |
| A | GLY165 |
| A | GLY167 |
| A | HIS168 |
| A | SER170 |
| A | VAL172 |
| A | ALA185 |
| A | LYS187 |
| A | LEU226 |
| A | GLU247 |
| A | VAL248 |
| A | LEU249 |
| A | GLY250 |
| A | ASN252 |
| A | GLU298 |
| A | LEU301 |
| A | ASP550 |
| A | MG743 |
| A | MG744 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ADN B 486 |
| Chain | Residue |
| B | TRP166 |
| B | ALA185 |
| B | LEU226 |
| B | GLU247 |
| B | VAL248 |
| B | LEU249 |
| B | HOH758 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 24 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGWGHFSTVWlAkdmvnnth..........VAMK |
| Chain | Residue | Details |
| A | LEU164-LYS187 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IiHtDIKpeNVLM |
| Chain | Residue | Details |
| A | ILE290-MET302 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10027","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | GLU298 | |
| A | ASP294 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| B | GLU298 | |
| B | ASP294 | |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | ASP294 | |
| A | LYS296 | |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| B | ASP294 | |
| B | LYS296 | |
| site_id | CSA5 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | THR567 | |
| A | ASP294 | |
| A | LYS296 | |
| site_id | CSA6 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| B | THR567 | |
| B | ASP294 | |
| B | LYS296 | |
| site_id | CSA7 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | ASP294 | |
| A | LYS296 | |
| A | ASN299 | |
| site_id | CSA8 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| B | ASP294 | |
| B | LYS296 | |
| B | ASN299 | |
