1Q84

Crystal structure of the mouse acetylcholinesterase-TZ2PA6 anti complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004104	molecular_function	cholinesterase activity
B	0004104	molecular_function	cholinesterase activity

Functional Information from PROSITE/UniProt

site_id	PS00122
Number of Residues	16
Details	CARBOXYLESTERASE_B_1 Carboxylesterases type-B serine active site. FGGdpmsVtLfGeSAG

Chain	Residue	Details
A	PHE190-GLY205

---

site_id	PS00941
Number of Residues	11
Details	CARBOXYLESTERASE_B_2 Carboxylesterases type-B signature 2. EDCLYLNVWtP

Chain	Residue	Details
A	GLU94-PRO104

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Acyl-ester intermediate"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Active site: {"description":"Charge relay system"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine"}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1qe3

Chain	Residue	Details
A	GLU334
A	HIS447
A	SER203

---

site_id	CSA2
Number of Residues	3
Details	Annotated By Reference To The Literature 1qe3

Chain	Residue	Details
B	GLU334
B	HIS447
B	SER203

---