1Q0T

Ternary Structure of T4DAM with AdoHcy and DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0003677	molecular_function	DNA binding
A	0006260	biological_process	DNA replication
A	0006298	biological_process	mismatch repair
A	0008168	molecular_function	methyltransferase activity
A	0009007	molecular_function	site-specific DNA-methyltransferase (adenine-specific) activity
A	0009008	molecular_function	DNA-methyltransferase activity
A	0009307	biological_process	DNA restriction-modification system
A	0016740	molecular_function	transferase activity
A	0019049	biological_process	virus-mediated perturbation of host defense response
A	0032259	biological_process	methylation
A	0039503	biological_process	obsolete suppression by virus of host innate immune response
A	0043565	molecular_function	sequence-specific DNA binding
A	0099018	biological_process	symbiont-mediated evasion of host restriction-modification system
A	1904047	molecular_function	S-adenosyl-L-methionine binding
B	0003676	molecular_function	nucleic acid binding
B	0003677	molecular_function	DNA binding
B	0006260	biological_process	DNA replication
B	0006298	biological_process	mismatch repair
B	0008168	molecular_function	methyltransferase activity
B	0009007	molecular_function	site-specific DNA-methyltransferase (adenine-specific) activity
B	0009008	molecular_function	DNA-methyltransferase activity
B	0009307	biological_process	DNA restriction-modification system
B	0016740	molecular_function	transferase activity
B	0019049	biological_process	virus-mediated perturbation of host defense response
B	0032259	biological_process	methylation
B	0039503	biological_process	obsolete suppression by virus of host innate immune response
B	0043565	molecular_function	sequence-specific DNA binding
B	0099018	biological_process	symbiont-mediated evasion of host restriction-modification system
B	1904047	molecular_function	S-adenosyl-L-methionine binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD D 1

Chain	Residue
D	DC423

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site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD C 2

Chain	Residue
C	DC403

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site_id	AC3
Number of Residues	19
Details	BINDING SITE FOR RESIDUE SAH A 300

Chain	Residue
A	SER37
A	VAL38
A	ASP50
A	ILE51
A	GLN52
A	HIS156
A	PHE157
A	ASP171
A	PRO173
A	TYR181
A	PHE184
A	TRP185
A	TYR7
A	ASN10
A	LYS11
A	PHE32
A	CYS33
A	GLY34
A	GLY35

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site_id	AC4
Number of Residues	17
Details	BINDING SITE FOR RESIDUE SAH B 301

Chain	Residue
B	TYR7
B	ASN10
B	LYS11
B	PHE32
B	CYS33
B	GLY35
B	LEU36
B	SER37
B	ASP50
B	ILE51
B	GLN52
B	HIS156
B	PHE157
B	ASP171
B	PRO173
B	TYR181
B	PHE184

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Functional Information from PROSITE/UniProt

site_id	PS00092
Number of Residues	7
Details	N6_MTASE N-6 Adenine-specific DNA methylases signature. VYVDPPY

Chain	Residue	Details
A	VAL168-TYR174

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	BINDING: BINDING => ECO:0007744|PDB:1Q0S, ECO:0007744|PDB:1Q0T, ECO:0007744|PDB:1YF3, ECO:0007744|PDB:1YFJ

Chain	Residue	Details
A	TYR7
A	PHE32
A	ASP50
A	TYR181
B	TYR7
B	PHE32
B	ASP50
B	TYR181

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site_id	SWS_FT_FI2
Number of Residues	6
Details	BINDING: BINDING => ECO:0007744|PDB:1Q0S, ECO:0007744|PDB:1YF3, ECO:0007744|PDB:1YFJ

Chain	Residue	Details
A	LYS11
A	HIS156
A	ASP171
B	LYS11
B	HIS156
B	ASP171

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