1Q05

Crystal structure of the Cu(I) form of E. coli CueR, a copper efflux regulator

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000976	molecular_function	transcription cis-regulatory region binding
A	0000987	molecular_function	cis-regulatory region sequence-specific DNA binding
A	0001216	molecular_function	DNA-binding transcription activator activity
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0005507	molecular_function	copper ion binding
A	0005737	cellular_component	cytoplasm
A	0006351	biological_process	DNA-templated transcription
A	0006355	biological_process	regulation of DNA-templated transcription
A	0032993	cellular_component	protein-DNA complex
A	0042802	molecular_function	identical protein binding
A	0045893	biological_process	positive regulation of DNA-templated transcription
A	0046872	molecular_function	metal ion binding
B	0000976	molecular_function	transcription cis-regulatory region binding
B	0000987	molecular_function	cis-regulatory region sequence-specific DNA binding
B	0001216	molecular_function	DNA-binding transcription activator activity
B	0003677	molecular_function	DNA binding
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0005507	molecular_function	copper ion binding
B	0005737	cellular_component	cytoplasm
B	0006351	biological_process	DNA-templated transcription
B	0006355	biological_process	regulation of DNA-templated transcription
B	0032993	cellular_component	protein-DNA complex
B	0042802	molecular_function	identical protein binding
B	0045893	biological_process	positive regulation of DNA-templated transcription
B	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CU1 B 301

Chain	Residue
A	SER77
B	CYS112
B	CYS120
B	ILE122

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CU1 A 302

Chain	Residue
A	CYS112
A	CYS120
A	PRO121
A	ILE122
B	SER77

---

Functional Information from PROSITE/UniProt

site_id	PS00552
Number of Residues	23
Details	HTH_MERR_1 MerR-type HTH domain signature. SdVAkiTGLTskaIRfYEek.GLV

Chain	Residue	Details
A	SER4-VAL26

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	136
Details	Domain: {"description":"HTH merR-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00254","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	38
Details	DNA binding: {"description":"H-T-H motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU00254","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {}

Chain

Residue

Details

---