Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005829 | cellular_component | cytosol |
| A | 0016491 | molecular_function | oxidoreductase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE NAP A 500 |
| Chain | Residue |
| A | GLY19 |
| A | TYR203 |
| A | GLY204 |
| A | LEU206 |
| A | CYS207 |
| A | ARG208 |
| A | GLY209 |
| A | LYS214 |
| A | ARG227 |
| A | LEU278 |
| A | TRP279 |
| A | THR20 |
| A | GLY280 |
| A | ARG282 |
| A | GLN286 |
| A | HOH510 |
| A | HOH679 |
| A | HOH682 |
| A | TRP21 |
| A | TRP28 |
| A | ASP52 |
| A | TYR57 |
| A | LYS84 |
| A | SER155 |
| A | GLN175 |
| site_id | AC2 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE NAP B 501 |
| Chain | Residue |
| B | GLY19 |
| B | THR20 |
| B | TRP21 |
| B | TRP28 |
| B | ASP52 |
| B | TYR57 |
| B | LYS84 |
| B | SER155 |
| B | ASN156 |
| B | GLN175 |
| B | TYR203 |
| B | GLY204 |
| B | LEU206 |
| B | CYS207 |
| B | ARG208 |
| B | GLY209 |
| B | THR212 |
| B | LYS214 |
| B | ARG227 |
| B | ILE261 |
| B | GLY280 |
| B | ARG282 |
| B | GLN286 |
| B | HOH504 |
| B | HOH574 |
| B | HOH576 |
| B | HOH701 |
Functional Information from PROSITE/UniProt
| site_id | PS00062 |
| Number of Residues | 18 |
| Details | ALDOKETO_REDUCTASE_2 Aldo/keto reductase family signature 2. MkelydagkIRAIGVSNF |
| Chain | Residue | Details |
| A | MSE140-PHE157 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"15019785","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 26 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15019785","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1PZ1","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Site: {"description":"Lowers pKa of active site Tyr","evidences":[{"source":"PubMed","id":"15019785","evidenceCode":"ECO:0000305"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1mrq |
| Chain | Residue | Details |
| A | LYS84 | |
| A | ASP52 | |
| A | TYR57 | |
| A | HIS125 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1mrq |
| Chain | Residue | Details |
| B | LYS84 | |
| B | ASP52 | |
| B | TYR57 | |
| B | HIS125 | |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1mrq |
| Chain | Residue | Details |
| A | LYS84 | |
| A | TYR57 | |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1mrq |
| Chain | Residue | Details |
| B | LYS84 | |
| B | TYR57 | |
