1PYM
PHOSPHOENOLPYRUVATE MUTASE FROM MOLLUSK IN WITH BOUND MG2-OXALATE
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0032923 | biological_process | organic phosphonate biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050188 | molecular_function | phosphoenolpyruvate mutase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0032923 | biological_process | organic phosphonate biosynthetic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0050188 | molecular_function | phosphoenolpyruvate mutase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE OXL A 1001 |
| Chain | Residue |
| A | TRP44 |
| A | SER46 |
| A | GLY47 |
| A | LEU48 |
| A | ASP85 |
| A | ARG159 |
| A | ALA238 |
| A | MG1003 |
| A | HOH1073 |
| A | HOH1086 |
| A | HOH1109 |
| A | HOH1245 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE OXL B 1002 |
| Chain | Residue |
| B | TRP44 |
| B | SER46 |
| B | GLY47 |
| B | LEU48 |
| B | ASP85 |
| B | ARG159 |
| B | ALA238 |
| B | MG1004 |
| B | HOH1010 |
| B | HOH1144 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 1003 |
| Chain | Residue |
| A | ASP85 |
| A | OXL1001 |
| A | HOH1073 |
| A | HOH1086 |
| A | HOH1158 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 1004 |
| Chain | Residue |
| B | ASP85 |
| B | OXL1002 |
| B | HOH1089 |
| B | HOH1094 |
| B | HOH1115 |
| site_id | PEP |
| Number of Residues | 16 |
| Details | CATALYTIC SITE |
| Chain | Residue |
| A | ASP58 |
| B | ASP85 |
| B | ASP87 |
| B | GLU114 |
| B | ARG159 |
| B | LYS120 |
| B | GLY47 |
| B | LEU48 |
| A | ASP85 |
| A | ASP87 |
| A | GLU114 |
| A | ARG159 |
| A | LYS120 |
| A | GLY47 |
| A | LEU48 |
| B | ASP58 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | a catalytic site defined by CSA, PubMed 10378273 |
| Chain | Residue | Details |
| A | ASP58 | |
| A | LEU48 | |
| A | GLY47 | |
| A | LYS120 |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | a catalytic site defined by CSA, PubMed 10378273 |
| Chain | Residue | Details |
| B | ASP58 | |
| B | LEU48 | |
| B | GLY47 | |
| B | LYS120 |
| site_id | MCSA1 |
| Number of Residues | 12 |
| Details | M-CSA 271 |
| Chain | Residue | Details |
| A | LEU54 | electrostatic stabiliser, hydrogen bond donor, steric role |
| A | ILE135 | electrostatic stabiliser, hydrogen bond donor, promote heterolysis |
| A | GLU171 | electrostatic stabiliser, hydrogen bond donor, promote heterolysis |
| A | TRP206 | electrostatic stabiliser, hydrogen bond donor, promote heterolysis |
| A | GLY55 | electrostatic stabiliser, steric role |
| A | VAL56 | electrostatic stabiliser, hydrogen bond donor, steric role |
| A | GLN66 | metal ligand, nucleofuge, nucleophile, promote heterolysis |
| A | ARG97 | electrostatic stabiliser, hydrogen bond donor, metal ligand |
| A | LEU99 | electrostatic stabiliser, hydrogen bond donor |
| A | ASP126 | electrostatic stabiliser, hydrogen bond donor |
| A | LEU132 | electrostatic stabiliser, promote heterolysis |
| A | ASP134 | electrostatic stabiliser, hydrogen bond donor, promote heterolysis |
| site_id | MCSA2 |
| Number of Residues | 12 |
| Details | M-CSA 271 |
| Chain | Residue | Details |
| B | LEU54 | electrostatic stabiliser, hydrogen bond donor, steric role |
| B | ILE135 | electrostatic stabiliser, hydrogen bond donor, promote heterolysis |
| B | GLU171 | electrostatic stabiliser, hydrogen bond donor, promote heterolysis |
| B | TRP206 | electrostatic stabiliser, hydrogen bond donor, promote heterolysis |
| B | GLY55 | electrostatic stabiliser, steric role |
| B | VAL56 | electrostatic stabiliser, hydrogen bond donor, steric role |
| B | GLN66 | metal ligand, nucleofuge, nucleophile, promote heterolysis |
| B | ARG97 | electrostatic stabiliser, hydrogen bond donor, metal ligand |
| B | LEU99 | electrostatic stabiliser, hydrogen bond donor |
| B | ASP126 | electrostatic stabiliser, hydrogen bond donor |
| B | LEU132 | electrostatic stabiliser, promote heterolysis |
| B | ASP134 | electrostatic stabiliser, hydrogen bond donor, promote heterolysis |
