1PYA
REFINED STRUCTURE OF THE PYRUVOYL-DEPENDENT HISTIDINE DECARBOXYLASE FROM LACTOBACILLUS 30A
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004398 | molecular_function | histidine decarboxylase activity |
| A | 0006520 | biological_process | amino acid metabolic process |
| A | 0006547 | biological_process | histidine metabolic process |
| A | 0016831 | molecular_function | carboxy-lyase activity |
| B | 0004398 | molecular_function | histidine decarboxylase activity |
| B | 0006520 | biological_process | amino acid metabolic process |
| B | 0006547 | biological_process | histidine metabolic process |
| B | 0016831 | molecular_function | carboxy-lyase activity |
| C | 0004398 | molecular_function | histidine decarboxylase activity |
| C | 0006520 | biological_process | amino acid metabolic process |
| C | 0006547 | biological_process | histidine metabolic process |
| C | 0016831 | molecular_function | carboxy-lyase activity |
| D | 0004398 | molecular_function | histidine decarboxylase activity |
| D | 0006520 | biological_process | amino acid metabolic process |
| D | 0006547 | biological_process | histidine metabolic process |
| D | 0016831 | molecular_function | carboxy-lyase activity |
| E | 0004398 | molecular_function | histidine decarboxylase activity |
| E | 0006520 | biological_process | amino acid metabolic process |
| E | 0006547 | biological_process | histidine metabolic process |
| E | 0016831 | molecular_function | carboxy-lyase activity |
| F | 0004398 | molecular_function | histidine decarboxylase activity |
| F | 0006520 | biological_process | amino acid metabolic process |
| F | 0006547 | biological_process | histidine metabolic process |
| F | 0016831 | molecular_function | carboxy-lyase activity |
Functional Information from PDB Data
| site_id | ACB |
| Number of Residues | 1 |
| Details | ACTIVE SITE 1 |
| Chain | Residue |
| B | PYR82 |
| site_id | ACD |
| Number of Residues | 1 |
| Details | ACTIVE SITE 2 |
| Chain | Residue |
| D | PYR82 |
| site_id | ACF |
| Number of Residues | 1 |
| Details | ACTIVE SITE 3 |
| Chain | Residue |
| F | PYR82 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Proton donor |
| Chain | Residue | Details |
| B | ASP198 | |
| D | ASP198 | |
| F | ASP198 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | MOD_RES: Pyruvic acid (Ser) => ECO:0000269|PubMed:6698997 |
| Chain | Residue | Details |
| B | PHE83 | |
| D | PHE83 | |
| F | PHE83 |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 3 |
| Details | M-CSA 49 |
| Chain | Residue | Details |
| B | PHE83 | covalently attached, electrofuge, electron pair acceptor, electron pair donor, electrophile, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay |
| B | VAL196 | electrostatic stabiliser, hydrogen bond donor |
| B | ASP198 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| site_id | MCSA2 |
| Number of Residues | 3 |
| Details | M-CSA 49 |
| Chain | Residue | Details |
| D | PHE83 | covalently attached, electrofuge, electron pair acceptor, electron pair donor, electrophile, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay |
| D | VAL196 | electrostatic stabiliser, hydrogen bond donor |
| D | ASP198 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| site_id | MCSA3 |
| Number of Residues | 3 |
| Details | M-CSA 49 |
| Chain | Residue | Details |
| F | PHE83 | covalently attached, electrofuge, electron pair acceptor, electron pair donor, electrophile, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay |
| F | VAL196 | electrostatic stabiliser, hydrogen bond donor |
| F | ASP198 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
