1PTX
CRYSTAL STRUCTURE OF TOXIN II FROM THE SCORPION ANDROCTONUS AUSTRALIS HECTOR REFINED AT 1.3 ANGSTROMS RESOLUTION
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006952 | biological_process | defense response |
| A | 0008200 | molecular_function | ion channel inhibitor activity |
| A | 0017080 | molecular_function | sodium channel regulator activity |
| A | 0019871 | molecular_function | sodium channel inhibitor activity |
| A | 0044487 | biological_process | venom-mediated perturbation of transmission of nerve impulse |
| A | 0044493 | biological_process | venom-mediated inhibition of voltage-gated sodium channel activity |
| A | 0044742 | biological_process | venom-mediated increase of sensory perception of pain |
| A | 0090729 | molecular_function | toxin activity |
| A | 0099106 | molecular_function | ion channel regulator activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 62 |
| Details | Domain: {"description":"LCN-type CS-alpha/beta","evidences":[{"source":"PROSITE-ProRule","id":"PRU01210","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Site: {"description":"Key residue for Nav1.7/SCN9A site 3","evidences":[{"source":"PubMed","id":"30733386","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Histidine amide","evidences":[{"source":"PubMed","id":"15725394","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
