1PTD

PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004436	molecular_function	phosphatidylinositol diacylglycerol-lyase activity
A	0005576	cellular_component	extracellular region
A	0006629	biological_process	lipid metabolic process
A	0008081	molecular_function	phosphoric diester hydrolase activity
A	0016042	biological_process	lipid catabolic process
A	0016829	molecular_function	lyase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor

Chain	Residue	Details
A	HIS32

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site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: Proton donor

Chain	Residue	Details
A	HIS82

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues	5
Details	M-CSA 26

Chain	Residue	Details
A	HIS32	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
A	ASP33	electrostatic stabiliser, hydrogen bond acceptor
A	ARG69	electrostatic stabiliser, hydrogen bond donor
A	HIS82	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
A	ASP274	electrostatic stabiliser, hydrogen bond acceptor

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