1PTD
PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004436 | molecular_function | phosphatidylinositol diacylglycerol-lyase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| A | 0016042 | biological_process | lipid catabolic process |
| A | 0016829 | molecular_function | lyase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 141 |
| Details | Domain: {"description":"PI-PLC X-box","evidences":[{"source":"PROSITE-ProRule","id":"PRU00270","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor"} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details |
| Chain | Residue | Details |
| A | ASP274 | |
| A | HIS32 | |
| A | HIS82 | |
| A | ARG69 |
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 26 |
| Chain | Residue | Details |
| A | HIS32 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | ASP33 | electrostatic stabiliser, hydrogen bond acceptor |
| A | ARG69 | electrostatic stabiliser, hydrogen bond donor |
| A | HIS82 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | ASP274 | electrostatic stabiliser, hydrogen bond acceptor |
