1PPZ
Trypsin complexes at atomic and ultra-high resolution
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004252 | molecular_function | serine-type endopeptidase activity |
A | 0005576 | cellular_component | extracellular region |
A | 0006508 | biological_process | proteolysis |
A | 0008233 | molecular_function | peptidase activity |
A | 0008236 | molecular_function | serine-type peptidase activity |
A | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 A 301 |
Chain | Residue |
A | GLY112 |
A | GLY113 |
A | HOH458 |
A | HOH481 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 3 |
Details | ACT_SITE: Charge relay system |
Chain | Residue | Details |
A | HIS56 | |
A | ASP99 | |
A | MIS195 |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | SITE: Required for specificity |
Chain | Residue | Details |
A | ASP189 |
Catalytic Information from CSA
site_id | MCSA1 |
Number of Residues | 6 |
Details | M-CSA 173 |
Chain | Residue | Details |
A | HIS56 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
A | ASP99 | activator, electrostatic stabiliser, hydrogen bond acceptor |
A | GLN192 | electrostatic stabiliser, hydrogen bond donor, transition state stabiliser |
A | GLY193 | electrostatic stabiliser, hydrogen bond donor, transition state stabiliser |
A | ASP194 | electrostatic stabiliser, hydrogen bond donor, transition state stabiliser |
A | MIS195 | electrostatic stabiliser, transition state stabiliser |