Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004068 | molecular_function | aspartate 1-decarboxylase activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0005829 | cellular_component | cytosol |
A | 0006523 | biological_process | alanine biosynthetic process |
A | 0015940 | biological_process | pantothenate biosynthetic process |
A | 0016540 | biological_process | protein autoprocessing |
A | 0016831 | molecular_function | carboxy-lyase activity |
B | 0004068 | molecular_function | aspartate 1-decarboxylase activity |
B | 0005737 | cellular_component | cytoplasm |
B | 0005829 | cellular_component | cytosol |
B | 0006523 | biological_process | alanine biosynthetic process |
B | 0015940 | biological_process | pantothenate biosynthetic process |
B | 0016540 | biological_process | protein autoprocessing |
B | 0016831 | molecular_function | carboxy-lyase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE SO4 A 271 |
Chain | Residue |
A | HIS21 |
A | TYR22 |
A | GLU23 |
A | GLY73 |
A | ALA74 |
A | HOH443 |
B | HIS11 |
B | ARG12 |
B | HOH172 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: Schiff-base intermediate with substrate; via pyruvic acid => ECO:0000269|PubMed:9546220 |
Chain | Residue | Details |
A | SER25 | |
B | SER25 | |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | ACT_SITE: Proton donor |
Chain | Residue | Details |
A | TYR58 | |
B | TYR58 | |
site_id | SWS_FT_FI3 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000250 |
Chain | Residue | Details |
A | THR57 | |
A | GLY73 | |
B | THR57 | |
B | GLY73 | |
Chain | Residue | Details |
A | SER25 | |
B | SER25 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1aw8 |
site_id | CSA2 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1aw8 |
Chain | Residue | Details |
A | TYR58 | |
site_id | CSA3 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1aw8 |
Chain | Residue | Details |
A | LYS9 | |
B | TYR58 | |
site_id | MCSA1 |
Number of Residues | 3 |
Details | M-CSA 409 |
Chain | Residue | Details |
A | LYS9 | electrostatic stabiliser |
A | SER25 | covalently attached, electrofuge, electrophile |
A | TYR58 | activator, increase nucleophilicity, proton acceptor, proton donor |
site_id | MCSA2 |
Number of Residues | 3 |
Details | M-CSA 409 |
Chain | Residue | Details |
B | LYS9 | electrostatic stabiliser |
B | SER25 | covalently attached, electrofuge, electrophile |
B | TYR58 | activator, increase nucleophilicity, proton acceptor, proton donor |