1POS
CRYSTAL STRUCTURE OF A NOVEL DISULFIDE-LINKED "TREFOIL" MOTIF FOUND IN A LARGE FAMILY OF PUTATIVE GROWTH FACTORS
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0008083 | molecular_function | growth factor activity |
| A | 0030277 | biological_process | maintenance of gastrointestinal epithelium |
| A | 0031723 | molecular_function | CXCR4 chemokine receptor binding |
| A | 0060455 | biological_process | negative regulation of gastric acid secretion |
| A | 0070098 | biological_process | chemokine-mediated signaling pathway |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005615 | cellular_component | extracellular space |
| B | 0008083 | molecular_function | growth factor activity |
| B | 0030277 | biological_process | maintenance of gastrointestinal epithelium |
| B | 0031723 | molecular_function | CXCR4 chemokine receptor binding |
| B | 0060455 | biological_process | negative regulation of gastric acid secretion |
| B | 0070098 | biological_process | chemokine-mediated signaling pathway |
Functional Information from PROSITE/UniProt
| site_id | PS00025 |
| Number of Residues | 21 |
| Details | P_TREFOIL_1 P-type 'Trefoil' domain signature. RvnCgFpgi.TsdqCftsgCCF |
| Chain | Residue | Details |
| A | ARG16-PHE36 | |
| A | ARG65-PHE85 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 88 |
| Details | Domain: {"description":"P-type 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00779","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 86 |
| Details | Domain: {"description":"P-type 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00779","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
