1PNH

SOLUTION STRUCTURE OF PO5-NH2, A SCORPION TOXIN ANALOG WITH HIGH AFFINITY FOR THE APAMIN-SENSITIVE POTASSIUM CHANNEL

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0008200	molecular_function	ion channel inhibitor activity
A	0015459	molecular_function	potassium channel regulator activity
A	0035821	biological_process	modulation of process of another organism
A	0090729	molecular_function	toxin activity
A	0099106	molecular_function	ion channel regulator activity

Functional Information from PROSITE/UniProt

site_id	PS01138
Number of Residues	21
Details	SCORP_SHORT_TOXIN Scorpion short toxins signature. CqlsCrslgll...GKCIgvkCeC

Chain	Residue	Details
A	CYS8-CYS28

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	30
Details	Peptide: {"description":"Potassium channel toxin alpha-KTx 5.2","featureId":"PRO_0000044928","evidences":[{"source":"PubMed","id":"8385026","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	3
Details	Region: {"description":"[R/K]XCQ motif","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	4
Details	Site: {"description":"Interacts with KCa2.2/KCNN2 and KCa2.3/KCNN3","evidences":[{"source":"PubMed","id":"11527975","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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