1PM1

Crystal structure of nitrophorin 2 L122V/L132V mutant complex with imidazole

Functional Information from GO Data

Chain	GOid	namespace	contents
X	0005576	cellular_component	extracellular region
X	0042311	biological_process	vasodilation
X	0046872	molecular_function	metal ion binding
X	0051381	molecular_function	histamine binding
X	0070026	molecular_function	nitric oxide binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	19
Details	BINDING SITE FOR RESIDUE HEM X 180

Chain	Residue
X	PHE27
X	LEU106
X	VAL122
X	LEU129
X	IMD181
X	HOH223
X	HOH291
X	HOH367
X	HOH391
X	HOH416
X	HOH433
X	TYR38
X	SER40
X	GLU53
X	LEU55
X	HIS57
X	ASN68
X	TYR85
X	TYR104

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE IMD X 181

Chain	Residue
X	ILE120
X	VAL122
X	GLY130
X	VAL132
X	HEM180

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING: proximal binding residue => ECO:0000269|PubMed:10884386, ECO:0007744|PDB:1EUO

Chain	Residue	Details
X	HIS57

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