1PJR
STRUCTURE OF DNA HELICASE
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000725 | biological_process | recombinational repair |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003678 | molecular_function | DNA helicase activity |
| A | 0004386 | molecular_function | helicase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006259 | biological_process | DNA metabolic process |
| A | 0006260 | biological_process | DNA replication |
| A | 0009314 | biological_process | response to radiation |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0016887 | molecular_function | ATP hydrolysis activity |
| A | 0032991 | cellular_component | protein-containing complex |
| A | 0033202 | cellular_component | DNA helicase complex |
| A | 0043138 | molecular_function | 3'-5' DNA helicase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10388562","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1QHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PJR","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10388562","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1QHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QHH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PJR","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10388562","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1QHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QHH","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10388562","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1QHG","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"1QHG","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10388562","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10388562","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1QHH","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10199404","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3PJR","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"9592155","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1QHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1QHH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PJR","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10199404","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10388562","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1QHH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PJR","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"1QHH","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"3PJR","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 1 |
| Details | Site: {"description":"ATP gamma phosphate sensor","evidences":[{"source":"PubMed","id":"10454638","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1qhg |
| Chain | Residue | Details |
| A | GLU224 | |
| A | LYS37 | |
| A | ARG610 |
| site_id | MCSA1 |
| Number of Residues | 6 |
| Details | M-CSA 833 |
| Chain | Residue | Details |
| A | LYS37 | electrostatic stabiliser |
| A | THR38 | metal ligand |
| A | ASP223 | electrostatic stabiliser |
| A | GLU224 | proton acceptor |
| A | GLN254 | electrostatic stabiliser |
| A | ARG610 | electrostatic stabiliser |
