Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000162 | biological_process | L-tryptophan biosynthetic process |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004425 | molecular_function | indole-3-glycerol-phosphate synthase activity |
| A | 0004640 | molecular_function | phosphoribosylanthranilate isomerase activity |
| A | 0006568 | biological_process | L-tryptophan metabolic process |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016831 | molecular_function | carboxy-lyase activity |
| A | 0016853 | molecular_function | isomerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 A 453 |
| Chain | Residue |
| A | LYS55 |
| A | SER215 |
| A | GLY216 |
| A | ILE235 |
| A | GLY236 |
| A | SER237 |
| A | HOH455 |
| A | HOH515 |
| A | HOH531 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 A 454 |
| Chain | Residue |
| A | GLY383 |
| A | GLY386 |
| A | GLY407 |
| A | ASN427 |
| A | SER428 |
| A | HOH483 |
| A | HOH502 |
| A | HOH706 |
| A | HOH948 |
| site_id | ASI |
| Number of Residues | 19 |
| Details | ACTIVE SITE OF PRAI |
| Chain | Residue |
| A | LYS258 |
| A | CYS260 |
| A | ILE282 |
| A | ARG289 |
| A | VAL291 |
| A | VAL310 |
| A | GLN332 |
| A | HIS334 |
| A | ASP379 |
| A | SER385 |
| A | ALA405 |
| A | GLY406 |
| A | GLY407 |
| A | ASP425 |
| A | ASN427 |
| A | SER428 |
| A | ALA429 |
| A | VAL430 |
| A | GLU431 |
| site_id | ASS |
| Number of Residues | 24 |
| Details | ACTIVE SITE OF IGPS |
| Chain | Residue |
| A | VAL4 |
| A | TYR92 |
| A | PHE93 |
| A | LYS114 |
| A | PHE116 |
| A | GLU163 |
| A | ASN184 |
| A | ARG186 |
| A | LEU188 |
| A | LEU191 |
| A | GLU214 |
| A | LEU5 |
| A | SER215 |
| A | LEU234 |
| A | GLY236 |
| A | SER237 |
| A | ALA238 |
| A | ILE8 |
| A | GLU53 |
| A | LYS55 |
| A | SER58 |
| A | PRO59 |
| A | SER60 |
| A | LYS61 |
Functional Information from PROSITE/UniProt
| site_id | PS00614 |
| Number of Residues | 19 |
| Details | IGPS Indole-3-glycerol phosphate synthase signature. FIlECKKASPSkgvirddF |
| Chain | Residue | Details |
| A | PHE50-PHE68 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 195 |
| Details | Region: {"description":"N-(5'-phosphoribosyl)anthranilate isomerase"} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 6 |
| Details | a catalytic site defined by CSA, PubMed 12054868 |
| Chain | Residue | Details |
| A | SER215 | |
| A | LYS114 | |
| A | GLU53 | |
| A | ASN184 | |
| A | LYS55 | |
| A | GLU163 | |
